non-ovlon and Menorrhagia

The effectiveness of hemostatic therapy in connection with the functional condition of the hypophysis is studied. The study included 92 women in their pubertal, reproductive, and climacteric years. Dysfunctional uterine hemorrhage in these patients was treated by various methods of hemostatic therapy. Radioimmunological determinations of gonadotrophic hormones in peripheral blood were performed to monitor the functional condition of the hypophysis during the hemorrhage phase and hemostatic therapy. The statistically processed data prove that hemostasis with symptomatic preparations is significantly less effective than synthetic progestins and hormonal methods, especially with the combined use of sex hormones. Hemostatic therapy with estrogenic hormones causes pronounced changes in the functional condition of the hypophysis, i.e., inhibition of folliculostimulatory activity. Hemostasis with booster doses of Non-ovlon had the strongest impact on the gonadotrophic function of the hypophysis. Combined use of sex hormones inhibits not only the folliculostimulatory function of the hypophysis, but also its luteinizing function. Comparative analysis of clinical effectiveness data for various treatment methods suggests that higher hemostatic effects are accompanied by significant inhibition of the gonadotrophic activity of the hypophysis.

Topics: Adolescent; Adult; Chlormadinone Acetate; Contraceptives, Oral, Combined; Drug Combinations; Drug Therapy, Combination; Estradiol Congeners; Female; Hemostatic Techniques; Humans; Menorrhagia; Middle Aged; Norethindrone; Testosterone Congeners