Page last updated: 2024-11-01

nomifensine and Tremor

nomifensine has been researched along with Tremor in 3 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"The nomifensine-treated depressed patients showed significant improvement over the placebo depressed patients early in and throughout treatment."2.65Nomifensine in geriatric inpatients: a placebo-controlled study. ( Jansen, W; Siegfried, K, 1984)
" Side effect information was collected at each visit."2.65An overview of side effects and long-term experience with nomifensine from United States clinical trials. ( Hardiman, S; Nash, RJ; Yakabow, AL, 1984)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jansen, W1
Siegfried, K1
Yakabow, AL1
Hardiman, S1
Nash, RJ1
Agnoli, A1
Ruggieri, S1
Baldassarre, M1
Rocco, A1
Del Roscio, S1
D'Urso, R1
Mearelli, S1
Falaschi, P1
Frajese, G1

Trials

2 trials available for nomifensine and Tremor

ArticleYear
Nomifensine in geriatric inpatients: a placebo-controlled study.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Aged; Clinical Trials as Topic; Cognition Disorders; Depressive Disorder; Double-Blind Method; Fatig

1984
An overview of side effects and long-term experience with nomifensine from United States clinical trials.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adult; Akathisia, Drug-Induced; Clinical Trials as Topic; Depressive Disorder; Dizziness; Headache;

1984

Other Studies

1 other study available for nomifensine and Tremor

ArticleYear
Presynaptic neuron and postsynaptic dopamine receptor function in long term treatment of Parkinson's disease: a neuroendocrine study.
    Progress in clinical and biological research, 1980, Volume: 39

    Topics: Aged; Apomorphine; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Levodopa; Male; Middle Age

1980