nomifensine has been researched along with Sleep Wake Disorders in 4 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Side effects include sleep disturbance, restlessness, and nausea; rare adverse reactions are in keeping with other antidepressants." | 3.75 | A review of the clinical safety and tolerability of nomifensine. ( Stonier, PD, 1984) |
| " Side effect information was collected at each visit." | 2.65 | An overview of side effects and long-term experience with nomifensine from United States clinical trials. ( Hardiman, S; Nash, RJ; Yakabow, AL, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piacentini, F | 1 |
| Prati, R | 1 |
| Prosdocimo, M | 1 |
| Stonier, PD | 1 |
| Yakabow, AL | 1 |
| Hardiman, S | 1 |
| Nash, RJ | 1 |
| Pepper, GA | 1 |
1 review available for nomifensine and Sleep Wake Disorders
| Article | Year |
|---|---|
A review of the clinical safety and tolerability of nomifensine.
Topics: Adult; Akathisia, Drug-Induced; Animals; Antidepressive Agents; Cardiovascular System; Clinical Tria | 1984 |
2 trials available for nomifensine and Sleep Wake Disorders
| Article | Year |
|---|---|
A review of the clinical safety and tolerability of nomifensine.
Topics: Adult; Akathisia, Drug-Induced; Animals; Antidepressive Agents; Cardiovascular System; Clinical Tria | 1984 |
An overview of side effects and long-term experience with nomifensine from United States clinical trials.
Topics: Adult; Akathisia, Drug-Induced; Clinical Trials as Topic; Depressive Disorder; Dizziness; Headache; | 1984 |
2 other studies available for nomifensine and Sleep Wake Disorders
| Article | Year |
|---|---|
[Use of antidepressive drugs in rehabilitation].
Topics: Depression; Female; Hemiplegia; Humans; Isoquinolines; Male; Nomifensine; Sleep Wake Disorders | 1983 |
Nomifensine (Merital): a second generation antidepressant.
Topics: Akathisia, Drug-Induced; Antidepressive Agents; Constipation; Depression; Headache; Humans; Kinetics | 1986 |