nomifensine has been researched along with Schizophrenia in 5 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2." | 1.28 | Effect of nomifensine on platelet monoamine oxidase activity in chronic schizophrenic patients. ( Filinger, EJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vinar, O | 1 |
| Gelenberg, AJ | 1 |
| Filinger, EJ | 1 |
| Hetey, L | 1 |
| Berg, R | 1 |
| Schlesinger, T | 1 |
| Guliamov, MG | 1 |
5 other studies available for nomifensine and Schizophrenia
| Article | Year |
|---|---|
Clinical experience with nomifensine.
Topics: Adolescent; Adult; Aged; Depression; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine; | 1979 |
Imperfect drugs in an imperfect world.
Topics: Bulimia; Bupropion; Clinical Trials as Topic; Clozapine; Depressive Disorder; Humans; Nomifensine; P | 1992 |
Effect of nomifensine on platelet monoamine oxidase activity in chronic schizophrenic patients.
Topics: Adult; Blood Platelets; Blood Proteins; Depressive Disorder; Humans; Male; Middle Aged; Monoamine Ox | 1989 |
Characterization of synaptosomal dopamine uptake in post-mortem brain regions of schizophrenics.
Topics: Animals; Brain; Dopamine; Dopamine Antagonists; Freezing; Male; Nomifensine; Preservation, Biologica | 1987 |
[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit].
Topics: Adjustment Disorders; Adolescent; Adult; Aminoquinolines; Antidepressive Agents; Bipolar Disorder; D | 1986 |