nomifensine has been researched along with Pregnancy in 21 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (80.95) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Larsen, TR | 1 |
| Rossen, S | 1 |
| Gramsbergen, JB | 1 |
| Craft, RM | 1 |
| Kostick, ML | 1 |
| Rogers, JA | 1 |
| White, CL | 1 |
| Tsutsui, KT | 1 |
| Choong, KC | 1 |
| Shen, RY | 1 |
| Camanni, F | 5 |
| Ghigo, E | 1 |
| Ciccarelli, E | 1 |
| Massara, F | 3 |
| Campagnoli, C | 2 |
| Molinatti, G | 1 |
| Müller, EE | 6 |
| Minuto, F | 1 |
| Barbarino, A | 1 |
| Baviera, G | 1 |
| Mazzocchi, G | 1 |
| De Marinis, L | 1 |
| Leonardi, R | 1 |
| Bernasconi, D | 1 |
| Menini, E | 1 |
| Maira, G | 1 |
| Anile, C | 1 |
| Genazzani, AR | 6 |
| Picciolini, E | 1 |
| Cocchi, D | 3 |
| Belforte, L | 1 |
| De Leo, V | 4 |
| Murru, S | 2 |
| Pontiroli, AE | 1 |
| Loda, G | 1 |
| Roggia, A | 1 |
| Scagliola, P | 1 |
| Falsetti, L | 1 |
| Iodice, M | 1 |
| Lombardi, G | 1 |
| Tommaselli, A | 1 |
| Rossi, R | 1 |
| Annunziato, L | 1 |
| Minozzi, M | 1 |
| Abraham, G | 1 |
| Ferrari, C | 1 |
| Crosignani, PG | 1 |
| Caldara, R | 1 |
| Picciotti, MC | 1 |
| Malinverni, A | 1 |
| Barattini, B | 1 |
| Rampini, P | 1 |
| Telloli, P | 1 |
| Molinatti, GM | 2 |
| Alonso, SJ | 1 |
| Castellano, MA | 1 |
| Quintero, M | 1 |
| Navarro, E | 1 |
| Dunne, MJ | 1 |
| Walker, J | 1 |
| Cowden, EA | 1 |
| Ratcliffe, JG | 1 |
| Kellner, HM | 1 |
| Baeder, C | 1 |
| Christ, O | 1 |
| Heptner, W | 1 |
| Hornke, I | 1 |
| Ings, RM | 2 |
| De Ceballos, ML | 1 |
| Benedi, A | 1 |
| Urdin, C | 1 |
| Del Rio, J | 1 |
| Butler, J | 1 |
| Leonard, BE | 1 |
| Petraglia, F | 1 |
| Sardelli, S | 1 |
| Mazzullo, G | 1 |
| Gioffrè, WR | 1 |
| D'Antona, N | 1 |
2 trials available for nomifensine and Pregnancy
| Article | Year |
|---|---|
Nomifensine test for investigation of hyperprolactinaemia.
Topics: Female; Humans; Isoquinolines; Male; Nomifensine; Postpartum Period; Pregnancy; Prolactin | 1979 |
Prolactin changes after administration of agonist and antagonist dopaminergic drugs in puerperal women.
Topics: Amphetamine; Carbidopa; Dopamine; Dopamine Antagonists; Female; Humans; Levodopa; Nomifensine; Postp | 1987 |
19 other studies available for nomifensine and Pregnancy
| Article | Year |
|---|---|
Dopamine release in organotypic cultures of foetal mouse mesencephalon: effects of depolarizing agents, pargyline, nomifensine, tetrodotoxin and calcium.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Dopamine; Dopamine Uptake Inhibitors; Female; Fetu | 2008 |
Forced swim test behavior in postpartum rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Desipramine; Female; Neurotransmitter Uptake Inhib | 2010 |
Methylphenidate restores ventral tegmental area dopamine neuron activity in prenatal ethanol-exposed rats by augmenting dopamine neurotransmission.
Topics: Amphetamine; Animals; Dopamine; Dopamine Agents; Dopamine Uptake Inhibitors; Drug Interactions; Elec | 2004 |
Defective regulation of prolactin secretion after successful removal of prolactinomas.
Topics: Adenoma; Adult; Domperidone; Female; Humans; Male; Nomifensine; Pituitary Neoplasms; Pregnancy; Prol | 1983 |
Multicentric experience on the acute effect of nomifensine in hyperprolactinemic women.
Topics: Adolescent; Adult; Female; Humans; Isoquinolines; Nomifensine; Pituitary Neoplasms; Postpartum Perio | 1984 |
A new pharmacological approach to the diagnosis of hyperprolactinaemic states: the nomifensine test.
Topics: Adult; Female; Follicle Stimulating Hormone; Humans; Isoquinolines; Luteinizing Hormone; Male; Menst | 1980 |
Dynamic tests of prolactin secretion in hyperprolactinemic states: carbidopa-L-dopa and indirectly acting dopamine agonists.
Topics: Adenoma; Adult; Carbidopa; Dopamine; Female; Humans; Kinetics; Levodopa; Methylphenidate; Nomifensin | 1982 |
Benserazide and nomifensine in the diagnosis of prolactin-secreting pituitary adenomas.
Topics: Adenoma; Benserazide; Female; Humans; Hydrazines; Isoquinolines; Nomifensine; Pituitary Neoplasms; P | 1982 |
Agreement of prolactin response to cimetidine and nomifensine in patients with prolactin-secreting tumors and idiopathic hyperprolactinemia.
Topics: Adolescent; Adult; Cimetidine; Female; Guanidines; Humans; Isoquinolines; Male; Nomifensine; Pituita | 1982 |
Use of bromocriptine as a diagnostic and therapeutic tool in hyperprolactinemic states.
Topics: Adenoma; Adolescent; Adult; Amenorrhea; Bromocriptine; Child; Female; Galactorrhea; Humans; Lactatio | 1982 |
Failure of nomifensine administration to discriminate between tumorous and nontumorous hyperprolactinemia.
Topics: Adenoma; Adolescent; Adult; Amenorrhea; Diagnosis, Differential; Female; Galactorrhea; Humans; Isoqu | 1980 |
Tests of prolactin secretion in the diagnosis of hyperprolactinemic states: nomifensine and domperidone.
Topics: Adenoma; Adult; Benzimidazoles; Domperidone; Female; Humans; Isoquinolines; Male; Menstruation; Midd | 1981 |
Effect of two indirectly acting dopamine agonists on prolactin secretion in normo- and hyperprolactinemic subjects: comparison with the effect of nomifensine.
Topics: Adult; Depression, Chemical; Dibenzocycloheptenes; Dopamine; Female; Humans; Isoquinolines; Male; Me | 1981 |
Action of antidepressant drugs on maternal stress-induced hypoactivity in female rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationsh | 1999 |
Nomifensine: diagnostic test in hyperprolactinemic states.
Topics: Adenoma; Female; Humans; Isoquinolines; Lactation; Nomifensine; Pituitary Neoplasms; Postpartum Peri | 1978 |
Kinetics and metabolism of nomifensine in animals.
Topics: Administration, Oral; Animals; Dogs; Female; Half-Life; Haplorhini; Injections, Intravenous; Isoquin | 1977 |
The comparative disposition of nomifensine (Merital) in the pregnant and non-pregnant rat.
Topics: Animals; Autoradiography; Female; Isoquinolines; Maternal-Fetal Exchange; Nomifensine; Pregnancy; Pr | 1979 |
Prenatal exposure of rats to antidepressant drugs down-regulates beta-adrenoceptors and 5-HT2 receptors in cerebral cortex. Lack of correlation between 5-HT2 receptors and serotonin-mediated behaviour.
Topics: Animals; Antidepressive Agents; Cerebral Cortex; Clomipramine; Female; Iprindole; Mianserin; Nomifen | 1985 |
Post-partum depression and the effect of nomifensine treatment.
Topics: Blood Platelets; Estradiol; Female; Humans; Nomifensine; Pregnancy; Progesterone; Prolactin; Psychot | 1986 |