nomifensine has been researched along with Parkinson Disease, Secondary in 5 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (40.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sotnikova, TD | 1 |
Beaulieu, JM | 1 |
Barak, LS | 1 |
Wetsel, WC | 1 |
Caron, MG | 1 |
Gainetdinov, RR | 1 |
Sarre, S | 1 |
De Klippel, N | 1 |
Herregodts, P | 1 |
Ebinger, G | 1 |
Michotte, Y | 1 |
Tedroff, J | 1 |
Aquilonius, SM | 1 |
Laihinen, A | 1 |
Rinne, U | 1 |
Hartvig, P | 1 |
Anderson, J | 1 |
Lundqvist, H | 1 |
Haaparanta, M | 1 |
Solin, O | 1 |
Antoni, G | 1 |
Schultz, W | 2 |
Scarnati, E | 2 |
Sundström, E | 2 |
Romo, R | 1 |
Tsutsumi, T | 1 |
Jonsson, G | 1 |
5 other studies available for nomifensine and Parkinson Disease, Secondary
Article | Year |
---|---|
Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease.
Topics: alpha-Methyltyrosine; Amphetamines; Animals; Antiparkinson Agents; Basal Ganglia; Blepharoptosis; Di | 2005 |
Biotransformation of locally applied L-dopa in the corpus striatum of the hemi-parkinsonian rat studied with microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Biotransformation; Corpus Striatum; Denervatio | 1994 |
Striatal kinetics of [11C]-(+)-nomifensine and 6-[18F]fluoro-L-dopa in Parkinson's disease measured with positron emission tomography.
Topics: Adult; Aged; Aged, 80 and over; Corpus Striatum; Dopamine; Female; Humans; Male; Middle Aged; Nomife | 1990 |
Protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism by the catecholamine uptake inhibitor nomifensine: behavioral analysis in monkeys with partial striatal dopamine depletions.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Catecholamines; Female; Macaca fascicularis; | 1989 |
The catecholamine uptake blocker nomifensine protects against MPTP-induced parkinsonism in monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Basal Ganglia | 1986 |