Page last updated: 2024-11-01

nomifensine and Pain

nomifensine has been researched along with Pain in 6 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gonzalez, JP3
Littler, ME1
Sewell, RD3
Spencer, PS2
Serrano, MI1
Quiroga, A1
Gibert-Rahola, J1
Cenci, MA1
Kalén, P1
Mandel, RJ1
Björklund, A1
Cunha, UV1

Other Studies

6 other studies available for nomifensine and Pain

ArticleYear
Stereoselective opiate antagonist induced hyperalgesia: evidence for a dopaminergic involvement.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:5

    Topics: Animals; Apomorphine; Dopamine; Injections, Intraventricular; Levodopa; Male; Mice; Naloxone; Narcot

1982
Evidence for central selective dopamine receptor stimulation in the mediation of nomifensine-induced hyperalgesia and the effects of opiate antagonists.
    Neuropharmacology, 1981, Volume: 20, Issue:11

    Topics: Animals; Brain; Bromocriptine; Domperidone; Flupenthixol; Hot Temperature; Isoquinolines; Male; Mice

1981
[Effect of nomifensine on the nociceptive action of acetic acid and acetylcholine bromide].
    Archivos de farmacologia y toxicologia, 1982, Volume: 8, Issue:3

    Topics: Acetates; Acetylcholine; Analgesics; Animals; Drug Interactions; Female; Isoquinolines; Male; Mice;

1982
Antinociceptive activity of opiates in the presence of the antidepressant agent nomifensine.
    Neuropharmacology, 1980, Volume: 19, Issue:7

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Isoquinolines; Male; Mice;

1980
Regional differences in the regulation of dopamine and noradrenaline release in medial frontal cortex, nucleus accumbens and caudate-putamen: a microdialysis study in the rat.
    Brain research, 1992, May-29, Volume: 581, Issue:2

    Topics: Animals; Caudate Nucleus; Cerebral Cortex; Dialysis; Dopamine; Electric Stimulation; Feeding Behavio

1992
Antidepressants: their uses in nonpsychiatric disorders of aging.
    Geriatrics, 1986, Volume: 41, Issue:10

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr

1986