nomifensine has been researched along with Pain in 6 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gonzalez, JP | 3 |
| Littler, ME | 1 |
| Sewell, RD | 3 |
| Spencer, PS | 2 |
| Serrano, MI | 1 |
| Quiroga, A | 1 |
| Gibert-Rahola, J | 1 |
| Cenci, MA | 1 |
| Kalén, P | 1 |
| Mandel, RJ | 1 |
| Björklund, A | 1 |
| Cunha, UV | 1 |
6 other studies available for nomifensine and Pain
| Article | Year |
|---|---|
Stereoselective opiate antagonist induced hyperalgesia: evidence for a dopaminergic involvement.
Topics: Animals; Apomorphine; Dopamine; Injections, Intraventricular; Levodopa; Male; Mice; Naloxone; Narcot | 1982 |
Evidence for central selective dopamine receptor stimulation in the mediation of nomifensine-induced hyperalgesia and the effects of opiate antagonists.
Topics: Animals; Brain; Bromocriptine; Domperidone; Flupenthixol; Hot Temperature; Isoquinolines; Male; Mice | 1981 |
[Effect of nomifensine on the nociceptive action of acetic acid and acetylcholine bromide].
Topics: Acetates; Acetylcholine; Analgesics; Animals; Drug Interactions; Female; Isoquinolines; Male; Mice; | 1982 |
Antinociceptive activity of opiates in the presence of the antidepressant agent nomifensine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Isoquinolines; Male; Mice; | 1980 |
Regional differences in the regulation of dopamine and noradrenaline release in medial frontal cortex, nucleus accumbens and caudate-putamen: a microdialysis study in the rat.
Topics: Animals; Caudate Nucleus; Cerebral Cortex; Dialysis; Dopamine; Electric Stimulation; Feeding Behavio | 1992 |
Antidepressants: their uses in nonpsychiatric disorders of aging.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr | 1986 |