Page last updated: 2024-11-01

nomifensine and Narcolepsy

nomifensine has been researched along with Narcolepsy in 2 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Narcolepsy: A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cunha, UV1
Sandyk, R1
Gillman, MA1

Other Studies

2 other studies available for nomifensine and Narcolepsy

ArticleYear
Antidepressants: their uses in nonpsychiatric disorders of aging.
    Geriatrics, 1986, Volume: 41, Issue:10

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr

1986
Nomifensine exacerbates narcolepsy.
    Neurology, 1985, Volume: 35, Issue:1

    Topics: Adult; Humans; Isoquinolines; Male; Narcolepsy; Nomifensine

1985