nomifensine has been researched along with Muscle Contraction in 9 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These results show that the adaptative changes of alpha-adrenoceptors in the rat anococcygeus muscle following long-term administration may depend on the efficiency to inhibit the neuronal uptake and the ability to antagonize alpha 1-adrenoceptors." | 1.28 | Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle. ( Badia, A; Sallés, J; Vila, E, 1990) |
| "Piribedil was found to be inactive." | 1.26 | The influence of dopamine and dopaminergic agonists on the contractions of field stimulated rat vas deferens. ( Dóda, M; Folly, G; György, L; Orr, Z, 1981) |
| "4) Amineptin was the only compound that increased blood pressure." | 1.26 | [A study of three potential antidepressants (amineptin, mianserin and nomifensin) on the cardiovascular system and isolated intestine (author's transl)]. ( Bourin, M; Delaigue, R; Schaff, G, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| György, L | 2 |
| Orr, Z | 2 |
| Folly, G | 1 |
| Dóda, M | 2 |
| Bourin, M | 1 |
| Delaigue, R | 1 |
| Schaff, G | 1 |
| Puche, E | 1 |
| García Morillas, M | 1 |
| Mundo, A | 1 |
| Saucedo, R | 1 |
| Revelles, H | 1 |
| Watanabe, H | 1 |
| Tateyama, M | 1 |
| Nagao, T | 1 |
| Ohta, S | 1 |
| Hirobe, M | 1 |
| Ono, H | 1 |
| Doggrell, SA | 1 |
| Woodruff, GN | 1 |
| Tayo, FM | 1 |
| Vila, E | 1 |
| Sallés, J | 1 |
| Badia, A | 1 |
| Kihara, M | 1 |
| Kashimoto, M | 1 |
| Kobayashi, S | 1 |
| Ishida, Y | 1 |
| Moritoki, H | 1 |
| Taira, Z | 1 |
9 other studies available for nomifensine and Muscle Contraction
| Article | Year |
|---|---|
The influence of dopamine and dopaminergic agonists on the contractions of field stimulated rat vas deferens.
Topics: Animals; Apomorphine; Bromocriptine; Dopamine; In Vitro Techniques; Male; Muscle Contraction; Nomife | 1981 |
[A study of three potential antidepressants (amineptin, mianserin and nomifensin) on the cardiovascular system and isolated intestine (author's transl)].
Topics: Animals; Antidepressive Agents; Dibenzocycloheptenes; Dogs; Duodenum; Hemodynamics; In Vitro Techniq | 1982 |
Influence of dopamine and dopaminergic agonists on relaxation of isolated rabbit ileum induced by sympathetic nerve stimulation.
Topics: Animals; Apomorphine; Bromocriptine; Cocaine; Dopamine; Electric Stimulation; Ileum; Muscle Contract | 1981 |
[Activity of nomifensine on the effects induced by noradrenaline on the atrium and the isolated ductus deferens of the rat].
Topics: Animals; Drug Synergism; Heart Atria; Heart Rate; Isoquinolines; Male; Muscle Contraction; Muscle, S | 1980 |
Methamphetamine antagonistic property of (+)- and (-)-4-phenyltetrahydroisoquinoline in rat anococcygeus muscle.
Topics: Animals; Cocaine; Electric Stimulation; In Vitro Techniques; Isoquinolines; Male; Methamphetamine; M | 1993 |
Effects of nomifensine on noradrenaline accumulation and contractile responses in the rat anococcygeus muscle.
Topics: Animals; Cocaine; Drug Interactions; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth; Nomife | 1978 |
Effects of nomifensine on the isolated vas deferens of the rat.
Topics: Animals; Desipramine; Dopamine; Drug Interactions; Guanethidine; In Vitro Techniques; Isoquinolines; | 1979 |
Effects of chronic antidepressant treatment on alpha 1- and alpha 2-adrenoceptors in the rat anococcygeus muscle.
Topics: Animals; Antidepressive Agents; Cocaine; Desipramine; Electric Stimulation; Male; Mianserin; Muscle | 1990 |
Resolution, absolute stereochemistry, and enantioselectivity of 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-4-ol.
Topics: Animals; Chromatography, High Pressure Liquid; Circular Dichroism; Drug Synergism; Molecular Structu | 1990 |