Page last updated: 2024-11-01

nomifensine and MPTP Neurotoxicity Syndrome

nomifensine has been researched along with MPTP Neurotoxicity Syndrome in 3 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McKinley, ET1
Baranowski, TC1
Blavo, DO1
Cato, C1
Doan, TN1
Rubinstein, AL1
Sriram, K1
Matheson, JM1
Benkovic, SA1
Miller, DB1
Luster, MI1
O'Callaghan, JP1
Lee, EH1
Lu, KT1

Other Studies

3 other studies available for nomifensine and MPTP Neurotoxicity Syndrome

ArticleYear
Neuroprotection of MPTP-induced toxicity in zebrafish dopaminergic neurons.
    Brain research. Molecular brain research, 2005, Nov-30, Volume: 141, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Dopamine; Dopamine Plasma Membrane Tra

2005
Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Corpus Striatum; Cytokines; Dopamine;

2006
Neurotoxicity of MPTP and uptake of MPPT into dopamine and norepinephrine neurons in mice.
    Advances in experimental medicine and biology, 1995, Volume: 363

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Biogenic Monoamines; Corpus Striatum; De

1995