nomifensine has been researched along with MPTP Neurotoxicity Syndrome in 3 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McKinley, ET | 1 |
| Baranowski, TC | 1 |
| Blavo, DO | 1 |
| Cato, C | 1 |
| Doan, TN | 1 |
| Rubinstein, AL | 1 |
| Sriram, K | 1 |
| Matheson, JM | 1 |
| Benkovic, SA | 1 |
| Miller, DB | 1 |
| Luster, MI | 1 |
| O'Callaghan, JP | 1 |
| Lee, EH | 1 |
| Lu, KT | 1 |
3 other studies available for nomifensine and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Neuroprotection of MPTP-induced toxicity in zebrafish dopaminergic neurons.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Dopamine; Dopamine Plasma Membrane Tra | 2005 |
Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Corpus Striatum; Cytokines; Dopamine; | 2006 |
Neurotoxicity of MPTP and uptake of MPPT into dopamine and norepinephrine neurons in mice.
Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Biogenic Monoamines; Corpus Striatum; De | 1995 |