Page last updated: 2024-11-01

nomifensine and Liver Diseases

nomifensine has been researched along with Liver Diseases in 2 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"The granulomas were located both in the portal tract and the liver parenchyma, and contained eosinophils and a few polynuclear giant cells."5.27[Granulomatous hepatitis caused by nomifensine]. ( Kummer, H; Marti, F; Wegmann, W, 1985)
"The granulomas were located both in the portal tract and the liver parenchyma, and contained eosinophils and a few polynuclear giant cells."1.27[Granulomatous hepatitis caused by nomifensine]. ( Kummer, H; Marti, F; Wegmann, W, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weiss, M1
Kummer, H1
Marti, F1
Wegmann, W1

Other Studies

2 other studies available for nomifensine and Liver Diseases

ArticleYear
Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction.
    Clinical pharmacokinetics, 1990, Volume: 18, Issue:5

    Topics: Absorption; Antipyrine; Biological Availability; Caffeine; Diphenhydramine; Dose-Response Relationsh

1990
[Granulomatous hepatitis caused by nomifensine].
    Schweizerische medizinische Wochenschrift, 1985, Nov-23, Volume: 115, Issue:47

    Topics: Aged; Biopsy; Chemical and Drug Induced Liver Injury; Female; Granuloma; Humans; Liver; Liver Diseas

1985