nomifensine has been researched along with Kidney Failure, Chronic in 2 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Plasma levels of nomifensine were examined using a radioimmunological determination method and pharmacokinetic parameters were calculated by computer program." | 2.64 | Pharmacokinetics of nomifensine in impaired renal function. ( Heptner, W; Lameire, N; Munche, M; Ringoir, S; Taeuber, K, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Leo, V | 1 |
| D'Ambrogio, G | 1 |
| De Leo, M | 1 |
| Franchi, F | 1 |
| Inaudi, P | 1 |
| La Rosa, R | 1 |
| D'Antona, N | 1 |
| Genazzani, AR | 1 |
| Ringoir, S | 1 |
| Lameire, N | 1 |
| Munche, M | 1 |
| Heptner, W | 1 |
| Taeuber, K | 1 |
1 trial available for nomifensine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pharmacokinetics of nomifensine in impaired renal function.
Topics: Clinical Trials as Topic; Glomerular Filtration Rate; Half-Life; Humans; Isoquinolines; Kidney Failu | 1977 |
1 other study available for nomifensine and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Hyperprolactinemia in chronic renal insufficiency: an interesting model of hypothalamo-hypophyseal dysfunction].
Topics: Adult; Bromocriptine; Domperidone; Female; Humans; Hypothalamo-Hypophyseal System; Kidney Failure, C | 1983 |