nomifensine has been researched along with Depressive Disorder, Major in 1 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
Excerpt | Relevance | Reference |
---|---|---|
" There were more withdrawals and dosage changes with nomifensine than with mianserin." | 6.66 | Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985) |
" There were more withdrawals and dosage changes with nomifensine than with mianserin." | 2.66 | Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Granier, F | 1 |
Girard, M | 1 |
Schmitt, L | 1 |
Boscredon, J | 1 |
Oules, J | 1 |
Escande, M | 1 |
1 trial available for nomifensine and Depressive Disorder, Major
Article | Year |
---|---|
Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Bipolar Disorder; Depre | 1985 |