Page last updated: 2024-11-01

nomifensine and Depression, Endogenous

nomifensine has been researched along with Depression, Endogenous in 83 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Research Excerpts

ExcerptRelevanceReference
" There were more withdrawals and dosage changes with nomifensine than with mianserin."6.66Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985)
"Nomifensine was introduced as an effective antidepressant drug with few side effects."5.26Drug fever due to nomifensine treatment in patients with endogenous depression. ( Lund, NO; Nielsen, JL, 1981)
"Nomifensine was compared to imipramine in treatment of 40 patients with endogenous major depressive disorder."5.06[A double-blind comparison study of nomifensine and imipramine in treating depressed patients]. ( Wang, XJ, 1989)
"Forty-two patients with depression and epilepsy were entered into an antidepressant trial of amitriptyline, nomifensine and placebo."5.05The treatment of depression in patients with epilepsy. A double-blind trial. ( Robertson, MM; Trimble, MR, 1985)
" In "endogenous" depression, a statistically significant linear dose-response relationship was found in all the efficacy variables assessed."2.66Therapeutic and side-effect profile of a selective and reversible MAO-A inhibitor, brofaromine. Results of dose-finding trials in depressed patients. ( Delini-Stula, A; Heath, WR; Schiwy, W, 1989)
" There were more withdrawals and dosage changes with nomifensine than with mianserin."2.66Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985)
"There was no tendency to physical drug dependence during treatment and during a one-week placebo phase after discontinuation of Psyton."2.65[Long-term treatment of depressive syndromes with Psyton (author's transl)]. ( Jellinger, K; Koeppen, D; Rössner, M, 1982)
"The imipramine treated group were significantly older."2.65Plasma levels and clinical response with imipramine in a study comparing efficacy with mianserin and nomifensine. ( Montgomery, DB; Montgomery, SA; Robinson, C; Roy, D; Wynne-Willson, S, 1983)
" The dosage was 150 mg daily in both treatment groups."2.65Nomifensine and amitriptyline in the treatment of depression. A multi-centre double-blind comparison. ( Agren, H; Bjaring, B; Källström, B; Lund, M; Månsby, J; Peterson, LE; Roos, BE; Wistedt, B, 1983)
" Nomifensine thus appeared safe and superior to placebo on several key measures of depressive symptomatology in this multicenter study of depressed outpatients."2.65Double-blind placebo-controlled multicenter evaluation of the efficacy and safety of nomifensine in depressed outpatients. ( Brauzer, B; Charalampous, KD; Goldstein, BJ; Kentsmith, D; Rosenthal, S, 1984)
"Nomifensine was at least as effective as imipramine in reducing depressive symptoms at average doses of 150 mg/day."2.65Multicenter double-blind comparison of nomifensine and imipramine for efficacy and safety in depressed outpatients. ( Abrahams, LM; Bremner, JD; Crupie, JE; McCawley, A; Proctor, RC; Sathananthan, GL, 1984)
"The nomifensine-treated depressed patients showed significant improvement over the placebo depressed patients early in and throughout treatment."2.65Nomifensine in geriatric inpatients: a placebo-controlled study. ( Jansen, W; Siegfried, K, 1984)
" The findings suggest a more favorable side effect profile for nomifensine, which was associated with a lower frequency of sedating and anticholinergic effects than was seen in the imipramine group."2.65A double-blind comparative evaluation of the efficacy and safety of nomifensine, imipramine, and placebo in depressed geriatric outpatients. ( Feighner, JP; Hendrickson, G; Merideth, CH, 1984)
" Side effect information was collected at each visit."2.65An overview of side effects and long-term experience with nomifensine from United States clinical trials. ( Hardiman, S; Nash, RJ; Yakabow, AL, 1984)
"50 patients suffering from endogenous depression were admitted to a double-blind study comparing the efficacy of nomifensine and maprotiline and the side effects associated with treatment."2.65Nomifensine and maprotiline in endogenous depression: comparative efficacy and side effects. ( Levin, A, 1982)
" The duration of treatment was 4 weeks and the dosage of both drugs ranged from 50 to 150 mg/day."2.65A double-blind clinical comparison between nomifensine and amitriptyline in the treatment of endogenous depressions. ( Ayuso Gutierez, JL; López-Ibor Aliño, JJ; Montejo Iglesias, ML; Ramons, JL, 1982)
"Nomifensine has demonstrated efficacy in several animal models that have been found to be predictive of clinical antidepressant activity, and has also been found to have a low potential for both cardiovascular and anticholinergic side effects."2.37Pharmacology of nomifensine: a review of animal studies. ( Fielding, S; Szewczak, MR, 1984)
"2."1.28Effect of nomifensine on platelet monoamine oxidase activity in chronic schizophrenic patients. ( Filinger, EJ, 1989)
"Bilaterally olfactory bulbectomized rats were compared with intact rats in their responsiveness to the acute and chronic administration of nomifensine and trazodone in the learned immobility test of Porsolt."1.27Effect of bilateral olfactory bulbectomy in the rat, alone or in combination with antidepressants, on the learned immobility model of depression. ( Earley, B; Górka, Z; Leonard, BE, 1985)
"After four weeks 66% of the endogenous depressions and 53% of the exhaustion depressions had completely regressed."1.26[Management of treatment-resistant depression without ECT (author's transl)]. ( Adams, C; Gastpar, M; Kielholz, P; Terzani, S, 1981)
"Nomifensine was introduced as an effective antidepressant drug with few side effects."1.26Drug fever due to nomifensine treatment in patients with endogenous depression. ( Lund, NO; Nielsen, JL, 1981)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199079 (95.18)18.7374
1990's3 (3.61)18.2507
2000's1 (1.20)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, J1
Kielholz, P1
Terzani, S1
Gastpar, M1
Adams, C1
Jellinger, K1
Koeppen, D1
Rössner, M1
Hanks, GW1
Leonard, BE2
Georgia, EH1
Knudsen, P1
Bjørndal, N1
Johnsen, T1
Pfeiffer Petersen, K1
Hirsch, SR1
Walsh, C1
Draper, R1
Montgomery, SA1
Roy, D3
Wynne-Willson, S1
Robinson, C1
Montgomery, DB3
Hamouz, W1
Van Dorth, R1
Pinder, RM1
Stulemeijer, SM1
Wistedt, B1
Agren, H1
Bjaring, B1
Källström, B1
Lund, M1
Månsby, J1
Peterson, LE1
Roos, BE1
Syvälahti, E1
Lindberg, R1
Iisalo, E1
Crook, T1
Fielding, S1
Szewczak, MR1
Feighner, JP2
Merideth, CH2
Claghorn, JL1
Goldstein, BJ1
Brauzer, B1
Kentsmith, D1
Rosenthal, S1
Charalampous, KD1
Bremner, JD1
Abrahams, LM1
Crupie, JE1
McCawley, A1
Proctor, RC1
Sathananthan, GL1
Fann, WE1
Lyle, FA1
Higginbotham, W1
Jansen, W2
Siegfried, K3
Cohn, JB1
Varga, L1
Lyford, A1
Hendrickson, G1
Gillings, D1
Grizzle, J1
Koch, G1
Rickels, K2
Amara, I1
Donelan, M1
Hardiman, S2
Nash, R1
Sollecito, W1
Stager, W1
Overall, JE1
Yakabow, AL1
Nash, RJ1
Quadbeck, H1
Lehmann, E1
Tegeler, J1
Beckmann, H2
Holzmüller, B2
Fleckenstein, P2
Valle-Jones, JC1
Craven, JR1
Wallis, TD1
Schiff, AA1
Rettori, V1
Rubio, M1
Seilicovich, A1
Malik, A1
de los Santos, A1
Kabes, J3
Dostal, T2
Balon, R3
Papezová, H2
Pöldinger, W1
Streichenwein, SM1
Dencker, SJ1
Lundin, L1
Jensen, K1
Klitgaard, NA1
Wraae, O1
Eggert Hansen, C1
Ahlfors, UG1
Tuomikoski, S1
Pihkanen, T1
Jorgensen, HA1
Ose, E1
Weise, CC1
Sandler, K1
Schless, A1
Zal, M1
Norstad, N1
Levin, A2
López-Ibor Aliño, JJ1
Ayuso Gutierez, JL1
Montejo Iglesias, ML1
Ramons, JL1
Shopsin, B1
Ong, SB1
Lee, CT1
Pogády, J1
Vencovský, E1
Zizka, V2
Montogomery, SA1
Rani, SJ1
Goldstein, SE1
Birnbom, F1
Laliberte, R1
Montgomery, S1
Cassano, GB2
Conti, L2
Dell'Osso, L1
Massimetti, G2
Scardigli, G1
Jans, G1
Fornaro, P1
Levine, J1
Thompson, PJ1
Trimble, MR2
Laakmann, G1
Eckstein, R1
Riess, H1
Sauer, H1
Mempel, W1
McIntyre, IM1
Burrows, GD2
Norman, TR2
Dumovic, P1
Vohra, J1
Nielsen, JL1
Lund, NO1
Ivanov, V1
Popov, G1
Brandes, JW1
Körst, HA1
Littmann, KP1
Bech, P1
Guelfi, JD1
Gelenberg, AJ1
Górka, Z1
Earley, B1
Filinger, EJ1
Nolen, WA2
Schiwy, W1
Heath, WR1
Delini-Stula, A1
Taneri, Z1
Köhler, R1
Wang, XJ1
Granier, F1
Girard, M1
Schmitt, L1
Boscredon, J1
Oules, J1
Escande, M1
Robertson, MM1
Ostrow, D1
Pope, HG1
Hudson, JI1
Cole, JO1
van de Putte, JJ1
Dijken, WA1
Kamp, JS1
Blansjaar, BA1
Kramer, HJ1
Haffmans, J1
Harvey, NS1
Faltus, F1
Filip, V1
Karen, P1
Kolomazník, M1
Korínková, V1
Libiger, J1
Molcan, J1
Zapletálek, M1
O'Connolly, M2
Mosseri, M1
Oppenheim, G1
Raz, E1
Kahan, K1
Guliamov, MG1
Funke, HJ1
Holtmann, W1
Ismail, S1
Leonhardt, KF1
Muth, H1
Omer, LM1
Ramm, H1
Jarvik, LF1
Martlew, VJ1
Zankovich, R1
Rüthlein, J1
Meesmann, M1
Gunzer, U1
Auer, IO1
Schlebusch, L1
Dennerstein, L1
Davies, BM1

Reviews

7 reviews available for nomifensine and Depression, Endogenous

ArticleYear
Pharmacology of nomifensine: a review of animal studies.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Acetylcholine; Adenylyl Cyclases; Aggression; Animals; Behavior, Animal; Brain Chemistry; Corpus Str

1984
Four new atypical antidepressants (trazodone, mianserin, nomifensine, caroxazone): results of controlled trials.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Antidepressive Agents; Benzeneacetamides; Clinical Trials as Topic; Depressive Disorder; Drug Therap

1982
Acute therapy of depression.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Depressive Disorder; Drug Admin

1993
Efficacy of tianeptine in comparative trials versus reference antidepressants. An overview.
    The British journal of psychiatry. Supplement, 1992, Issue:15

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Relationship, Dr

1992
Antidepressant drug therapy for bulimia: current status.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:7

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method

1986
Psychiatric disorders in parkinsonism. 1. Functional illnesses and personality.
    Psychosomatics, 1986, Volume: 27, Issue:2

    Topics: Antidepressive Agents; Clozapine; Depressive Disorder; Dopamine; Electroconvulsive Therapy; Female;

1986
Antidepressant therapy: benefits and risks in perspective.
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 320

    Topics: Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Depressive Disorder; Dibenzazepines

1985

Trials

51 trials available for nomifensine and Depression, Endogenous

ArticleYear
[Long-term treatment of depressive syndromes with Psyton (author's transl)].
    Wiener medizinische Wochenschrift (1946), 1982, Apr-30, Volume: 132, Issue:8

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones;

1982
Double-blind comparison of the efficacy and safety of nomifensine maleate vs. placebo in depressed outpatients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adolescent; Adult; Ambulatory Care; Child; Clinical Trials as Topic; Depressive Disorder; Drug Erupt

1984
Zimeldine versus nomifensine. A double-blind study of depressed inpatients.
    Neuropsychobiology, 1984, Volume: 11, Issue:4

    Topics: Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Dose-Response Relationship, Drug; D

1984
Parasuicide. A review of treatment interventions.
    Journal of affective disorders, 1982, Volume: 4, Issue:4

    Topics: Adolescent; Adult; Aftercare; Behavior Therapy; Clinical Trials as Topic; Crisis Intervention; Depre

1982
Plasma levels and clinical response with imipramine in a study comparing efficacy with mianserin and nomifensine.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 2

    Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blind Method; Dru

1983
A double-blind trial of mianserin and nomifensine in depressed outpatients.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 2

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blind M

1983
Nomifensine and amitriptyline in the treatment of depression. A multi-centre double-blind comparison.
    Acta psychiatrica Scandinavica, 1983, Volume: 68, Issue:3

    Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Fati

1983
Clinical effects and serum levels of nomifensine in depressive patients.
    The Journal of international medical research, 1983, Volume: 11, Issue:5

    Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Humans; Isoquinolines; Middle Aged; Nomi

1983
Nomifensine: the preclinical and clinical profile of a second generation antidepressant.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Aged; Clinical Trials as Topic; Depressive Disorder; Humans; Isoquinolines; Nomifensine

1984
Nomifensine in the depressed elderly patient: discussion.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Aged; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Humans; Isoqu

1984
Multicenter placebo-controlled evaluation of nomifensine treatment in depressed outpatients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Double-Blin

1984
Double-blind placebo-controlled multicenter evaluation of the efficacy and safety of nomifensine in depressed outpatients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Ambulatory Care; Capsules; Clinical Trials as Topic;

1984
Multicenter double-blind comparison of nomifensine and imipramine for efficacy and safety in depressed outpatients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Double-Blin

1984
Nomifensine vs. imipramine in depressed inpatients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adult; Akathisia, Drug-Induced; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method;

1984
Nomifensine in geriatric inpatients: a placebo-controlled study.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Aged; Clinical Trials as Topic; Cognition Disorders; Depressive Disorder; Double-Blind Method; Fatig

1984
A two-center double-blind study of nomifensine, imipramine, and placebo in depressed geriatric outpatients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Aged; Akathisia, Drug-Induced; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Doubl

1984
A double-blind comparative evaluation of the efficacy and safety of nomifensine, imipramine, and placebo in depressed geriatric outpatients.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Aged; Akathisia, Drug-Induced; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Doubl

1984
Pooling 12 nomifensine studies for efficacy generalizability.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adolescent; Adult; Age Factors; Aged; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder

1984
Efficacy of nomifensine in different depressive syndromes.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Humans; Isoqu

1984
An overview of side effects and long-term experience with nomifensine from United States clinical trials.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Adult; Akathisia, Drug-Induced; Clinical Trials as Topic; Depressive Disorder; Dizziness; Headache;

1984
Comparison of the antidepressant action of tryptophan, tryptophan/5-hydroxytryptophan combination and nomifensine.
    Neuropsychobiology, 1984, Volume: 11, Issue:2

    Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination

1984
Clinical investigations into antidepressive mechanisms. II. Dexamethasone suppression test predicts response to nomifensine or amitriptyline.
    Acta psychiatrica Scandinavica, 1984, Volume: 70, Issue:4

    Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Dexamet

1984
Mixed anxiety/depressive illness in general practice. A therapeutic comparison of nomifensine with fluphenazine/nortriptyline.
    Acta psychiatrica Scandinavica, 1983, Volume: 68, Issue:6

    Topics: Adolescent; Adult; Aged; Anxiety Disorders; Depressive Disorder; Double-Blind Method; Drug Combinati

1983
A clinical trial comparing nomifensine and nortriptyline.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 1

    Topics: Adolescent; Adult; Age Factors; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method;

1982
Nomifensine and imipramine in endogenous depression. A double-blind Scandinavian multicentre study.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Human

1982
Nomifensine, imipramine and placebo in depressed outpatients.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 1

    Topics: Adult; Ambulatory Care; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female;

1982
Nomifensine and maprotiline in endogenous depression: comparative efficacy and side effects.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 1

    Topics: Adolescent; Adult; Aged; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Double-Blind Me

1982
A double-blind clinical comparison between nomifensine and amitriptyline in the treatment of endogenous depressions.
    International pharmacopsychiatry, 1982, Volume: 17 Suppl 1

    Topics: Adult; Age Factors; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Metho

1982
A double-blind comparison of nomifensine and amitriptyline in the treatment of depression.
    Acta psychiatrica Scandinavica, 1981, Volume: 63, Issue:3

    Topics: Adult; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Hu

1981
[Clinical experience with treatment of depressions by nomiphenzine (author's transl)].
    Ceskoslovenska psychiatrie, 1981, Volume: 77, Issue:1

    Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Isoquinolines; Male; Middle Ag

1981
[Results of the clinical trial with nomifensine (author's transl)].
    Ceskoslovenska psychiatrie, 1981, Volume: 77, Issue:1

    Topics: Adult; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Isoquinolines; Male; Middle Ag

1981
[Mianserin: review and discussion of its double-blind studies versus nomifensine].
    L'Encephale, 1981, Volume: 7, Issue:4 Suppl

    Topics: Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blind Method; Female; Humans;

1981
Nomifensine in the treatment of depressed geriatric patients.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:7

    Topics: Adjustment Disorders; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Bli

1982
Supersensitivity and nomifensine in depressed patients.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine

1982
Four new atypical antidepressants (trazodone, mianserin, nomifensine, caroxazone): results of controlled trials.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Antidepressive Agents; Benzeneacetamides; Clinical Trials as Topic; Depressive Disorder; Drug Therap

1982
Comparative double-blind study on efficacy and side-effects of trazodone, nomifensine, mianserin in elderly patients.
    Advances in biochemical psychopharmacology, 1982, Volume: 32

    Topics: Aged; Clinical Trials as Topic; Depressive Disorder; Dibenzazepines; Double-Blind Method; Female; Hu

1982
A double-blind clinical trial of nomifensine vs. amitriptyline in depressed patients.
    Pharmacopsychiatria, 1982, Volume: 15, Issue:3

    Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Drug Therapy

1982
Tranylcypromine in depression resistant to cyclic antidepressions.
    Progress in neuro-psychopharmacology & biological psychiatry, 1989, Volume: 13, Issue:1-2

    Topics: 5-Hydroxytryptophan; Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug

1989
Therapeutic and side-effect profile of a selective and reversible MAO-A inhibitor, brofaromine. Results of dose-finding trials in depressed patients.
    Journal of neural transmission. Supplementum, 1989, Volume: 28

    Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Mal

1989
Fluoxetine versus nomifensine in outpatients with neurotic or reactive depressive disorder.
    International clinical psychopharmacology, 1989, Volume: 4 Suppl 1

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Depressive Disorder; Double-Blind Method; Female; Flu

1989
[A double-blind comparison study of nomifensine and imipramine in treating depressed patients].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1989, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Depressive Disorder; Double-Blind Method; Electrocardiography; Female; Humans; Im

1989
Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial.
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 320

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Bipolar Disorder; Depre

1985
The treatment of depression in patients with epilepsy. A double-blind trial.
    Journal of affective disorders, 1985, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depressive Disorder; Double-Blind

1985
The new generation antidepressants: promising innovations or disappointments?
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:10 Pt 2

    Topics: Alprazolam; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trials as Topic;

1985
Antidepressant drug therapy for bulimia: current status.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:7

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method

1986
Where are those new antidepressants we were promised?
    Archives of general psychiatry, 1988, Volume: 45, Issue:2

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Human

1988
Treatment strategy in depression. II. MAO inhibitors in depression resistant to cyclic antidepressants: two controlled crossover studies with tranylcypromine versus L-5-hydroxytryptophan and nomifensine.
    Acta psychiatrica Scandinavica, 1988, Volume: 78, Issue:6

    Topics: 5-Hydroxytryptophan; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Dose-Response Relat

1988
[Comparison of nomifensine, maprotiline and imipramine in a double-blind study of patients with endogenous depression].
    Ceskoslovenska psychiatrie, 1986, Volume: 82, Issue:2

    Topics: Adult; Anthracenes; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Huma

1986
Cognitive and psychomotor effects of different antidepressants in the treatment of old age depression.
    International clinical psychopharmacology, 1986, Volume: 1, Issue:3

    Topics: Aged; Anthracenes; Antidepressive Agents; Clinical Trials as Topic; Cognition; Depressive Disorder;

1986
Double-blind comparison of diclofensine with nomifensine in outpatients with dysphoric mood.
    Pharmacopsychiatry, 1986, Volume: 19, Issue:3

    Topics: Adult; Aged; Depressive Disorder; Female; Humans; Isoquinolines; Male; Middle Aged; Nomifensine

1986
Mianserin is better tolerated and more effective in depression than a nomifensine-clobazam combination: a double-blind study.
    Acta psychiatrica Scandinavica. Supplementum, 1985, Volume: 320

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clobazam; Depressi

1985

Other Studies

27 other studies available for nomifensine and Depression, Endogenous

ArticleYear
The politics and bio-ethics of regulatory trust: case-studies of pharmaceuticals.
    Medicine, health care, and philosophy, 2008, Volume: 11, Issue:4

    Topics: Clinical Trials as Topic; Depressive Disorder; Disclosure; Dopamine Uptake Inhibitors; Drug Industry

2008
[Management of treatment-resistant depression without ECT (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, May-22, Volume: 106, Issue:21

    Topics: Antipsychotic Agents; Clomipramine; Depressive Disorder; Female; Humans; Male; Maprotiline; Nomifens

1981
Nomifensine for side-effects of depot neuroleptics.
    The British journal of psychiatry : the journal of mental science, 1982, Volume: 141

    Topics: Antipsychotic Agents; Depressive Disorder; Humans; Isoquinolines; Nomifensine

1982
Pharmacology of new antidepressants.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder; Disease Models, Animal; Dopamine; Humans

1984
Effect of nomifensine on cortisol, prolactin and biogenic amines in neurotic depressed patients.
    Neuropsychobiology, 1983, Volume: 10, Issue:4

    Topics: Adult; Biogenic Amines; Depressive Disorder; Humans; Hydrocortisone; Isoquinolines; Middle Aged; Nom

1983
[A profile of the clinical effectiveness of second generation antidepressive agents].
    Ceskoslovenska psychiatrie, 1984, Volume: 80, Issue:1

    Topics: Adult; Anthracenes; Depressive Disorder; Female; Humans; Isoquinolines; Male; Maprotiline; Middle Ag

1984
Dexamethasone suppression test predicts response to nomifensine or amitriptyline.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 144

    Topics: Amitriptyline; Depressive Disorder; Dexamethasone; Double-Blind Method; Humans; Isoquinolines; Nomif

1984
Second generation antidepressants.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:12 Pt 2

    Topics: Antidepressive Agents, Tricyclic; Catecholamines; Depressive Disorder; Double-Blind Method; Fluoxeti

1980
Non-MAOI antidepressant drugs and cognitive functions: a review.
    Psychological medicine, 1982, Volume: 12, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Cognition; Cognition Disorders; Depressive Disorder; Dose-Resp

1982
[Effect of antidepressants on the secretion of pituitary hormones in healthy subjects, neurotic depressive patients and endogenous depressive patients (author's transl)].
    Der Nervenarzt, 1980, Volume: 51, Issue:12

    Topics: Adult; Anthracenes; Clomipramine; Depressive Disorder; Desipramine; Female; Growth Hormone; Humans;

1980
[Nomifensin-induced immune haemolytic anaemias (author's transl)].
    Klinische Wochenschrift, 1981, Jun-01, Volume: 59, Issue:11

    Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic, Autoimmune; Coombs Test; Depressive Disorder; Humans;

1981
Plasma nomifensine concentration. Cardiological effects and clinical response.
    International pharmacopsychiatry, 1980, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Bundle of His; Depressive Disorder; Electrocardiography; Female; Heart; Humans; I

1980
Drug fever due to nomifensine treatment in patients with endogenous depression.
    International pharmacopsychiatry, 1981, Volume: 16, Issue:1

    Topics: Aged; Anemia, Hemolytic; Depressive Disorder; Female; Fever; Humans; Isoquinolines; Middle Aged; Nom

1981
[Comparative results of the treatment of anxiety in the depressive syndrome with Tolvon, Vivalan and Alival].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1981, Volume: 22, Issue:D

    Topics: Aged; Anxiety Disorders; Depressive Disorder; Dibenzazepines; Humans; Isoquinolines; Mianserin; Midd

1981
Do have antidepressants of the second generation anxiolytic properties?
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1981, Volume: 22, Issue:E

    Topics: Adult; Anthracenes; Anxiety; Depressive Disorder; Humans; Isoquinolines; Maprotiline; Middle Aged; M

1981
[Jaundice following nomifensine].
    Die Medizinische Welt, 1980, Oct-31, Volume: 31, Issue:44

    Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Depressive Disorder; Female; Humans; Isoquinoli

1980
Imperfect drugs in an imperfect world.
    The Journal of clinical psychiatry, 1992, Volume: 53, Issue:2

    Topics: Bulimia; Bupropion; Clinical Trials as Topic; Clozapine; Depressive Disorder; Humans; Nomifensine; P

1992
Effect of bilateral olfactory bulbectomy in the rat, alone or in combination with antidepressants, on the learned immobility model of depression.
    Neuropsychobiology, 1985, Volume: 13, Issue:1-2

    Topics: Amygdala; Animals; Depressive Disorder; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Is

1985
Effect of nomifensine on platelet monoamine oxidase activity in chronic schizophrenic patients.
    General pharmacology, 1989, Volume: 20, Issue:6

    Topics: Adult; Blood Platelets; Blood Proteins; Depressive Disorder; Humans; Male; Middle Aged; Monoamine Ox

1989
Cognitive symptoms in late-life depression and their treatment.
    Journal of affective disorders, 1985, Volume: Suppl 1

    Topics: Age Factors; Aged; Cognition Disorders; Depressive Disorder; Humans; Nomifensine

1985
Diarrhea and lethal bone marrow depression induced by nomifensine maleate.
    Israel journal of medical sciences, 1987, Volume: 23, Issue:8

    Topics: Aged; Bone Marrow Diseases; Depressive Disorder; Diarrhea; Humans; Male; Nomifensine; Pancytopenia

1987
[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:4

    Topics: Adjustment Disorders; Adolescent; Adult; Aminoquinolines; Antidepressive Agents; Bipolar Disorder; D

1986
Allergic reactions to nomifensine in the elderly.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:4

    Topics: Aged; Depressive Disorder; Drug Hypersensitivity; Humans; Nomifensine

1986
Immune haemolytic anaemia and nomifensine treatment in north west England 1984-85: report of six cases.
    Journal of clinical pathology, 1986, Volume: 39, Issue:10

    Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Antibodies; Depressive Disorder; England; Female; Humans

1986
[Nomifensine side effects and no end?].
    Medizinische Klinik (Munich, Germany : 1983), 1986, Sep-12, Volume: 81, Issue:18-19

    Topics: Depressive Disorder; Humans; Nomifensine

1986
[Nomifensine-induced fever with pericardial effusion, basal lung infiltration and pseudo-Pelger-Huet anomaly. A case report].
    Medizinische Klinik (Munich, Germany : 1983), 1986, Sep-12, Volume: 81, Issue:18-19

    Topics: Depressive Disorder; Female; Fever; Humans; Middle Aged; Nomifensine; Pelger-Huet Anomaly; Pericardi

1986
Nomifensine (Merital), a new non-tricyclic antidepressant.
    The Medical letter on drugs and therapeutics, 1985, Aug-30, Volume: 27, Issue:695

    Topics: Depressive Disorder; Humans; Isoquinolines; Kinetics; Nomifensine

1985