Page last updated: 2024-11-01

nomifensine and Cognition Disorders

nomifensine has been researched along with Cognition Disorders in 6 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"The nomifensine-treated depressed patients showed significant improvement over the placebo depressed patients early in and throughout treatment."2.65Nomifensine in geriatric inpatients: a placebo-controlled study. ( Jansen, W; Siegfried, K, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nikiforuk, A1
Popik, P1
Guzmán-Ramos, K1
Moreno-Castilla, P1
Castro-Cruz, M1
McGaugh, JL1
Martínez-Coria, H1
LaFerla, FM1
Bermúdez-Rattoni, F1
Bain, JN1
Prendergast, MA1
Terry, AV1
Arneric, SP1
Smith, MA1
Buccafusco, JJ1
Jansen, W1
Siegfried, K2
Thompson, PJ1
Trimble, MR1

Trials

1 trial available for nomifensine and Cognition Disorders

ArticleYear
Nomifensine in geriatric inpatients: a placebo-controlled study.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:4 Pt 2

    Topics: Aged; Clinical Trials as Topic; Cognition Disorders; Depressive Disorder; Double-Blind Method; Fatig

1984

Other Studies

5 other studies available for nomifensine and Cognition Disorders

ArticleYear
Long-lasting cognitive deficit induced by stress is alleviated by acute administration of antidepressants.
    Psychoneuroendocrinology, 2011, Volume: 36, Issue:1

    Topics: Animals; Antidepressive Agents; Attention; Behavior, Animal; Citalopram; Cognition Disorders; Desipr

2011
Restoration of dopamine release deficits during object recognition memory acquisition attenuates cognitive impairment in a triple transgenic mice model of Alzheimer's disease.
    Learning & memory (Cold Spring Harbor, N.Y.), 2012, Sep-14, Volume: 19, Issue:10

    Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brai

2012
Enhanced attention in rhesus monkeys as a common factor for the cognitive effects of drugs with abuse potential.
    Psychopharmacology, 2003, Volume: 169, Issue:2

    Topics: Animals; Atomoxetine Hydrochloride; Attention; Caffeine; Cognition; Cognition Disorders; Color Perce

2003
Non-MAOI antidepressant drugs and cognitive functions: a review.
    Psychological medicine, 1982, Volume: 12, Issue:3

    Topics: Amitriptyline; Antidepressive Agents; Cognition; Cognition Disorders; Depressive Disorder; Dose-Resp

1982
Cognitive symptoms in late-life depression and their treatment.
    Journal of affective disorders, 1985, Volume: Suppl 1

    Topics: Age Factors; Aged; Cognition Disorders; Depressive Disorder; Humans; Nomifensine

1985