Page last updated: 2024-11-01

nomifensine and Chronic Kidney Failure

nomifensine has been researched along with Chronic Kidney Failure in 2 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Research Excerpts

ExcerptRelevanceReference
" Plasma levels of nomifensine were examined using a radioimmunological determination method and pharmacokinetic parameters were calculated by computer program."2.64Pharmacokinetics of nomifensine in impaired renal function. ( Heptner, W; Lameire, N; Munche, M; Ringoir, S; Taeuber, K, 1977)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Leo, V1
D'Ambrogio, G1
De Leo, M1
Franchi, F1
Inaudi, P1
La Rosa, R1
D'Antona, N1
Genazzani, AR1
Ringoir, S1
Lameire, N1
Munche, M1
Heptner, W1
Taeuber, K1

Trials

1 trial available for nomifensine and Chronic Kidney Failure

ArticleYear
Pharmacokinetics of nomifensine in impaired renal function.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Clinical Trials as Topic; Glomerular Filtration Rate; Half-Life; Humans; Isoquinolines; Kidney Failu

1977

Other Studies

1 other study available for nomifensine and Chronic Kidney Failure

ArticleYear
[Hyperprolactinemia in chronic renal insufficiency: an interesting model of hypothalamo-hypophyseal dysfunction].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Aug-30, Volume: 59, Issue:8

    Topics: Adult; Bromocriptine; Domperidone; Female; Humans; Hypothalamo-Hypophyseal System; Kidney Failure, C

1983