Page last updated: 2024-11-01

nomifensine and Chemical Dependence

nomifensine has been researched along with Chemical Dependence in 6 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Research Excerpts

ExcerptRelevanceReference
"There was no tendency to physical drug dependence during treatment and during a one-week placebo phase after discontinuation of Psyton."2.65[Long-term treatment of depressive syndromes with Psyton (author's transl)]. ( Jellinger, K; Koeppen, D; Rössner, M, 1982)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bain, JN1
Prendergast, MA1
Terry, AV1
Arneric, SP1
Smith, MA1
Buccafusco, JJ1
Jellinger, K1
Koeppen, D1
Rössner, M1
Spyraki, C1
Fibiger, HC1
Rothman, RB1
Lamb, RJ1
Griffiths, RR1
Böning, J1
Fuchs, G1

Trials

1 trial available for nomifensine and Chemical Dependence

ArticleYear
[Long-term treatment of depressive syndromes with Psyton (author's transl)].
    Wiener medizinische Wochenschrift (1946), 1982, Apr-30, Volume: 132, Issue:8

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Benzodiazepinones;

1982

Other Studies

5 other studies available for nomifensine and Chemical Dependence

ArticleYear
Enhanced attention in rhesus monkeys as a common factor for the cognitive effects of drugs with abuse potential.
    Psychopharmacology, 2003, Volume: 169, Issue:2

    Topics: Animals; Atomoxetine Hydrochloride; Attention; Caffeine; Cognition; Cognition Disorders; Color Perce

2003
Intravenous self-administration of nomifensine in rats: implications for abuse potential in humans.
    Science (New York, N.Y.), 1981, Jun-05, Volume: 212, Issue:4499

    Topics: Animals; Humans; Injections, Intravenous; Isoquinolines; Male; Nomifensine; Pimozide; Rats; Reinforc

1981
High affinity dopamine reuptake inhibitors as potential cocaine antagonists: a strategy for drug development.
    Life sciences, 1990, Volume: 46, Issue:20

    Topics: Benztropine; Bupropion; Cocaine; Dopamine; Drug Evaluation, Preclinical; Humans; Mazindol; Nomifensi

1990
Self-administration in baboons and the discriminative stimulus effects in rats of bupropion, nomifensine, diclofensine and imipramine.
    Psychopharmacology, 1990, Volume: 102, Issue:2

    Topics: Animals; Antidepressive Agents; Bupropion; Conditioning, Operant; Discrimination, Psychological; Imi

1990
Nomifensine and psychological dependence--a case report.
    Pharmacopsychiatry, 1986, Volume: 19, Issue:5

    Topics: Adult; Female; Humans; Nomifensine; Substance Withdrawal Syndrome; Substance-Related Disorders

1986