Page last updated: 2024-11-01

nomifensine and Cerebral Ischemia

nomifensine has been researched along with Cerebral Ischemia in 3 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Research Excerpts

ExcerptRelevanceReference
"Whereas anoxia decreased extracellular 3,4-dihydroxyphenylacetic acid levels by 50%, aglycemia doubled it, and ischemia returned this aglycemia-induced enhancement to its control level."1.30Anoxia-induced dopamine release from rat striatal slices: involvement of reverse transport mechanism. ( Büyükuysal, RL; Mete, B, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, KW1
Kim, DC1
Kim, YH1
Eun, YA1
Kim, HI1
Cho, KP1
Kondoh, T1
Lee, SH1
Low, WC1
Büyükuysal, RL1
Mete, B1

Other Studies

3 other studies available for nomifensine and Cerebral Ischemia

ArticleYear
Ca2+-dependent and -independent mechanisms of ischaemia-evoked release of [3H]-dopamine from rat striatal slices.
    Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:4

    Topics: Animals; Brain Ischemia; Calcium; Calcium Channel Blockers; Corpus Striatum; Culture Techniques; Cyc

1995
Alterations in striatal dopamine release and reuptake under conditions of mild, moderate, and severe cerebral ischemia.
    Neurosurgery, 1995, Volume: 37, Issue:5

    Topics: Animals; Brain Damage, Chronic; Brain Ischemia; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitor

1995
Anoxia-induced dopamine release from rat striatal slices: involvement of reverse transport mechanism.
    Journal of neurochemistry, 1999, Volume: 72, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biological Transport; Brain Ischemia; Corpus Striatum; Dizo

1999