nomifensine has been researched along with Brain Disorders in 3 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " All of these effects of ATR were observed at levels that were not toxic to the tissue, as LDH release into the medium (lactate dehydrogenase, an index of non-specific cytotoxicity) was not affected by ATR." | 1.34 | Dopaminergic toxicity of the herbicide atrazine in rat striatal slices. ( Carr, RL; Filipov, NM; Sistrunk, SC; Stewart, MA, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Filipov, NM | 1 |
| Stewart, MA | 1 |
| Carr, RL | 1 |
| Sistrunk, SC | 1 |
| Meloni, R | 1 |
| Gale, K | 1 |
| Brooks, DJ | 1 |
| Salmon, EP | 1 |
| Mathias, CJ | 1 |
| Quinn, N | 1 |
| Leenders, KL | 1 |
| Bannister, R | 1 |
| Marsden, CD | 1 |
| Frackowiak, RS | 1 |
3 other studies available for nomifensine and Brain Disorders
| Article | Year |
|---|---|
Dopaminergic toxicity of the herbicide atrazine in rat striatal slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atrazine; Brain Diseases; Corpus Striatum; Dopamine; Dopami | 2007 |
Cocaine-induced turning behavior in rats with 6-hydroxydopamine lesions: effect of transplants of fetal substantia nigra.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Diseases; Brain Tissue Transplantation; C | 1991 |
The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson's disease, studied with PET.
Topics: Adult; Aged; Atrophy; Autonomic Nervous System; Autonomic Nervous System Diseases; Brain Diseases; C | 1990 |