Page last updated: 2024-11-01

nomifensine and Blepharoptosis

nomifensine has been researched along with Blepharoptosis in 4 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Blepharoptosis: Drooping of the upper lid due to deficient development or paralysis of the levator palpebrae muscle.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maryanoff, BE2
McComsey, DF2
Gardocki, JF2
Shank, RP2
Costanzo, MJ1
Nortey, SO1
Schneider, CR2
Setler, PE2
Kunstmann, R1
Gerhards, H1
Kruse, H1
Leven, M1
Paulus, EF1
Schacht, U1
Schmitt, K1
Witte, PU1
Castanzo, MJ1
Sotnikova, TD1
Beaulieu, JM1
Barak, LS1
Wetsel, WC1
Caron, MG1
Gainetdinov, RR1

Other Studies

4 other studies available for nomifensine and Blepharoptosis

ArticleYear
Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Brain; Catecholamines; Chemical Phenomena; Chemistry

1987
Resolution, absolute stereochemistry, and enantioselective activity of nomifensine and hexahydro-1H-indeno[1,2-b]pyridines.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Animals; Blepharoptosis; Brain; Chemical Phenomena; Chemistry; Dopamine; Drug Synergism; Indans; Ind

1987
Pyrroloisoquinoline antidepressants. Potent, enantioselective inhibition of tetrabenazine-induced ptosis and neuronal uptake of norepinephrine, dopamine, and serotonin.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:8

    Topics: Animals; Antidepressive Agents; Blepharoptosis; Catecholamines; Dopamine; Isoquinolines; Mice; Motor

1984
Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease.
    PLoS biology, 2005, Volume: 3, Issue:8

    Topics: alpha-Methyltyrosine; Amphetamines; Animals; Antiparkinson Agents; Basal Ganglia; Blepharoptosis; Di

2005