nomifensine has been researched along with Bipolar Disorder in 7 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There were more withdrawals and dosage changes with nomifensine than with mianserin." | 6.66 | Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985) |
| " There were more withdrawals and dosage changes with nomifensine than with mianserin." | 2.66 | Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial. ( Boscredon, J; Escande, M; Girard, M; Granier, F; Oules, J; Schmitt, L, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lylloff, K | 1 |
| Jersild, C | 1 |
| Bacher, T | 1 |
| Slot, O | 1 |
| Knudsen, P | 1 |
| Bjørndal, N | 1 |
| Johnsen, T | 1 |
| Pfeiffer Petersen, K | 1 |
| Beckmann, H | 1 |
| Holzmüller, B | 1 |
| Fleckenstein, P | 1 |
| Cassano, GB | 1 |
| Conti, L | 1 |
| Massimetti, G | 1 |
| Fornaro, P | 1 |
| Levine, J | 1 |
| Granier, F | 1 |
| Girard, M | 1 |
| Schmitt, L | 1 |
| Boscredon, J | 1 |
| Oules, J | 1 |
| Escande, M | 1 |
| Guliamov, MG | 1 |
| Koritar, E | 1 |
4 trials available for nomifensine and Bipolar Disorder
| Article | Year |
|---|---|
Zimeldine versus nomifensine. A double-blind study of depressed inpatients.
Topics: Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Dose-Response Relationship, Drug; D | 1984 |
Clinical investigations into antidepressive mechanisms. II. Dexamethasone suppression test predicts response to nomifensine or amitriptyline.
Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Dexamet | 1984 |
A double-blind clinical trial of nomifensine vs. amitriptyline in depressed patients.
Topics: Adult; Aged; Amitriptyline; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Drug Therapy | 1982 |
Depression and anxiety: mianserin and nomifensine compared in a double-blind multicentre trial.
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Bipolar Disorder; Depre | 1985 |
3 other studies available for nomifensine and Bipolar Disorder
| Article | Year |
|---|---|
Massive intravascular haemolysis during treatment of nomifensine.
Topics: Adult; Anemia, Hemolytic; Bipolar Disorder; Female; Humans; Immunoglobulin M; Isoquinolines; Nomifen | 1982 |
[Comparative evaluation of the therapeutic efficacy of the antidepressants adepren, linamiphen and emovit].
Topics: Adjustment Disorders; Adolescent; Adult; Aminoquinolines; Antidepressive Agents; Bipolar Disorder; D | 1986 |
Nomifensine-induced dyskinesia.
Topics: Aged; Bipolar Disorder; Dyskinesia, Drug-Induced; Humans; Isoquinolines; Male; Nomifensine | 1985 |