nomifensine has been researched along with Anemia, Hemolytic, Autoimmune in 14 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Anemia, Hemolytic, Autoimmune: Acquired hemolytic anemia due to the presence of AUTOANTIBODIES which agglutinate or lyse the patient's own RED BLOOD CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nomifensine has been incriminated in causing immune hemolysis in a large number of patients." | 1.27 | On the mechanisms of sensitization and attachment of antibodies to RBC in drug-induced immune hemolytic anemia. ( Mueller-Eckhardt, C; Salama, A, 1987) |
| "Nomifensine is a widely used antidepressant agent with few side-effects but haemolytic anaemia with acute renal failure has been reported with both intermittent therapeutic dosage and self-inflicted overdose." | 1.27 | Intravascular haemolysis and acute renal failure induced by nomifensine. ( Briggs, JD; Dominiczak, AF; Fulton, JD; Junor, BJ; Lucie, NP, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Salama, A | 6 |
| Mayer, B | 1 |
| Habibi, B | 1 |
| Cartron, JP | 1 |
| Bretagne, M | 1 |
| Rouger, P | 1 |
| Salmon, C | 1 |
| Eckstein, R | 1 |
| Riess, H | 1 |
| Sauer, H | 1 |
| Mempel, W | 1 |
| Kroll, H | 1 |
| Berghöfer, H | 1 |
| Ernst-Schlegel, M | 1 |
| Mueller-Eckhardt, C | 5 |
| Bournerias, F | 1 |
| Nabibi, B | 1 |
| Fulton, JD | 1 |
| Briggs, JD | 1 |
| Dominiczak, AF | 1 |
| Junor, BJ | 1 |
| Lucie, NP | 1 |
| Oberhofer, R | 1 |
| Amor, H | 1 |
| Prinoth, O | 1 |
| Martlew, VJ | 1 |
| Sokol, RJ | 1 |
| Hewitt, S | 1 |
| Booker, DJ | 1 |
| Stamps, R | 1 |
| Taylor, M | 1 |
| Stewart, RM | 1 |
| Ross, JR | 1 |
14 other studies available for nomifensine and Anemia, Hemolytic, Autoimmune
| Article | Year |
|---|---|
Diagnostic pitfalls of drug-induced immune hemolytic anemia.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Antigen-Antibody Complex; Antihypertensive Agents; Antimetaboli | 2014 |
Anti-nomifensine antibody causing immune hemolytic anemia and renal failure.
Topics: Agglutination Tests; Anemia, Hemolytic, Autoimmune; Antibodies; Antibody Formation; Binding, Competi | 1981 |
[Nomifensin-induced immune haemolytic anaemias (author's transl)].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic, Autoimmune; Coombs Test; Depressive Disorder; Humans; | 1981 |
[Detection of drug-induced antibodies to erythrocytes in the gel test].
Topics: Anemia, Hemolytic, Autoimmune; Autoantibodies; Carbimazole; Catechin; Cefotaxime; Coombs Test; Diclo | 1993 |
Nomifensine-induced immune haemolytic anaemia and impaired renal function.
Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Female; Humans; Isoquinolines; Middle Aged; Nomi | 1979 |
Rh blood group-specific antibodies in immune hemolytic anemia induced by nomifensine.
Topics: Anemia, Hemolytic, Autoimmune; Autoantibodies; Erythrocyte Membrane; Hemolysis; Humans; Immunoglobul | 1986 |
On the mechanisms of sensitization and attachment of antibodies to RBC in drug-induced immune hemolytic anemia.
Topics: Anemia, Hemolytic, Autoimmune; Antibody Specificity; Antigens, Surface; Autoantibodies; Catechin; Er | 1987 |
Intravascular haemolysis and acute renal failure induced by nomifensine.
Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Depression; Female; Humans; Middle Aged; Nomifen | 1986 |
[Hemolytic anemia with kidney failure after nomifensine].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic, Autoimmune; Female; Humans; Nomifensine | 1986 |
[Hemolytic anemia and renal failure caused by nomifensine].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Female; Humans; Male; | 1986 |
Immune haemolytic anaemia and nomifensine treatment in north west England 1984-85: report of six cases.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Antibodies; Depressive Disorder; England; Female; Humans | 1986 |
Two types of nomifensine-induced immune haemolytic anaemias: drug-dependent sensitization and/or autoimmunization.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Autoantibodies; Coombs Test; Female; Humans; Immunoglobu | 1986 |
Fatal immune haemolysis associated with nomifensine.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Female; Humans; Isoquinolines; Nomifensine | 1985 |
Fatal immune haemolysis associated with nomifensine.
Topics: Anemia, Hemolytic, Autoimmune; Female; Humans; Middle Aged; Nomifensine | 1985 |