nomifensine has been researched along with Anemia, Hemolytic, Acquired in 19 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nomifensine was introduced as an effective antidepressant drug with few side effects." | 5.26 | Drug fever due to nomifensine treatment in patients with endogenous depression. ( Lund, NO; Nielsen, JL, 1981) |
| "Nomifensine is an antidepressant drug (widely used in Europe, but not yet available in the United States), which has been linked to intravascular hemolysis." | 1.27 | The role of metabolite-specific antibodies in nomifensine-dependent immune hemolytic anemia. ( Mueller-Eckhardt, C; Salama, A, 1985) |
| "Nomifensine was introduced as an effective antidepressant drug with few side effects." | 1.26 | Drug fever due to nomifensine treatment in patients with endogenous depression. ( Lund, NO; Nielsen, JL, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (89.47) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lylloff, K | 1 |
| Jersild, C | 1 |
| Bacher, T | 1 |
| Slot, O | 1 |
| Salama, A | 6 |
| Mueller-Eckhardt, C | 6 |
| Kissel, K | 1 |
| Pralle, H | 1 |
| Seeger, W | 1 |
| Wälti, M | 1 |
| Neftel, K | 1 |
| Cohen, M | 1 |
| de Weck, AL | 1 |
| Perisić, M | 1 |
| Pretorius, ML | 1 |
| Nielsen, JL | 1 |
| Lund, NO | 1 |
| Prescott, LF | 1 |
| Illingworth, RN | 1 |
| Critchley, JA | 1 |
| Frazer, I | 1 |
| Stirling, ML | 1 |
| Giers, G | 2 |
| Santoso, S | 1 |
| Mueller-Eckhardt, G | 1 |
| Schendel, DJ | 1 |
| Fass, G | 1 |
| Hendra, N | 1 |
| Bloomfield, RJ | 1 |
| Wilson, IJ | 1 |
| Oberhofer, R | 1 |
| Prinoth, O | 1 |
| Amor, H | 1 |
| Köber, M | 1 |
| Reinhold, HM | 1 |
| Schneider, H | 1 |
| Woodliff, HJ | 1 |
| Wallace, PF | 1 |
| Petz, LD | 1 |
19 other studies available for nomifensine and Anemia, Hemolytic, Acquired
| Article | Year |
|---|---|
Massive intravascular haemolysis during treatment of nomifensine.
Topics: Adult; Anemia, Hemolytic; Bipolar Disorder; Female; Humans; Immunoglobulin M; Isoquinolines; Nomifen | 1982 |
Ex vivo antigen preparation for the serological detection of drug-dependent antibodies in immune haemolytic anaemias.
Topics: Anemia, Hemolytic; Antibodies; Diuretics; Epitopes; Female; Humans; Hydrochlorothiazide; Immunologic | 1984 |
[Demonstration of drug-specific IgE and IgG antibodies using RIA: clinical importance as shown with nomifensin (Alival)].
Topics: Alveolitis, Extrinsic Allergic; Anemia, Hemolytic; Antibody Formation; Antibody Specificity; Chemica | 1983 |
[Nomifensine-induced hemolytic anemia].
Topics: Adult; Anemia, Hemolytic; Female; Humans; Isoquinolines; Nomifensine | 1984 |
Drug fever due to nomifensine treatment in patients with endogenous depression.
Topics: Aged; Anemia, Hemolytic; Depressive Disorder; Female; Fever; Humans; Isoquinolines; Middle Aged; Nom | 1981 |
Acute haemolysis and renal failure after nomifensine overdosage.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Autoantibodies; Female; Humans; Isoquinolines; Kidney | 1980 |
Follow-up study on 24 patients with nomifensine-induced immune haemolytic anaemia.
Topics: Anemia, Hemolytic; Drug Administration Routes; Female; Follow-Up Studies; Humans; Male; Nomifensine | 1991 |
Antigenic determinants responsible for the reactions of drug-dependent antibodies with blood cells.
Topics: Anemia, Hemolytic; Antibodies; Cross Reactions; Drug Hypersensitivity; Epitopes; Erythrocytes; Human | 1991 |
Lessons from nomifensine.
Topics: Anemia, Hemolytic; Antibodies; Humans; Legislation, Drug; Nomifensine; Product Surveillance, Postmar | 1988 |
Major histocompatibility complex markers in patients with nomifensine-induced immune hemolytic anemia.
Topics: Adult; Aged; Anemia, Hemolytic; Complement System Proteins; Female; Histocompatibility Antigens; HLA | 1988 |
Merital withdrawn by manufacturer.
Topics: Anemia, Hemolytic; Drug Hypersensitivity; Drug Industry; Humans; Nomifensine | 1986 |
Nomifensine withdrawn by manufacturer.
Topics: Anemia, Hemolytic; Humans; Legislation, Drug; Nomifensine; United States; United States Food and Dru | 1986 |
[Hemolytic anemia and renal failure caused by nomifensine].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Female; Humans; Male; | 1986 |
Nomifensine, acute hemolytic anemia, and renal failure.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Drug Hypersensitivity; Female; Humans; Nomifensine | 1986 |
[Hemolytic anemia and renal insufficiency caused by nomifensine. Description of a case].
Topics: Acute Kidney Injury; Anemia, Hemolytic; Female; Humans; Middle Aged; Nomifensine | 1986 |
[Nomifensine-induced hemolysis with acute renal failure].
Topics: Acute Kidney Injury; Adjustment Disorders; Adult; Anemia, Hemolytic; Female; Hemolysis; Humans; Nomi | 1986 |
Haemolytic anaemia caused by nomifensine.
Topics: Anemia, Hemolytic; Depression; Female; Humans; Middle Aged; Nomifensine | 1986 |
The role of metabolite-specific antibodies in nomifensine-dependent immune hemolytic anemia.
Topics: Acute Disease; Acute Kidney Injury; Adult; Aged; Anemia, Hemolytic; Antibodies; Antibody Specificity | 1985 |
Drug-induced immune hemolysis.
Topics: Anemia, Hemolytic; Erythrocytes; Hemolysis; Humans; Nomifensine; Penicillins | 1985 |