Page last updated: 2024-11-01

nomifensine and Allergy, Drug

nomifensine has been researched along with Allergy, Drug in 10 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Research Excerpts

ExcerptRelevanceReference
"During 1979 4 patients were observed who developed short episodes of fever as high as 104 degrees F after oral intake of 25--100 mg nomifensine (Alival)."7.66[Drug fever caused by the antidepressive agent nomifensine (Alival)]. ( Fehlmann, U; Hoigné, R; Hunziker, T; Kummer, H; Spengler, H, 1980)
"During 1979 4 patients were observed who developed short episodes of fever as high as 104 degrees F after oral intake of 25--100 mg nomifensine (Alival)."3.66[Drug fever caused by the antidepressive agent nomifensine (Alival)]. ( Fehlmann, U; Hoigné, R; Hunziker, T; Kummer, H; Spengler, H, 1980)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wälti, M1
Neftel, K1
Cohen, M1
de Weck, AL1
Perisić, M1
Nielsen, JL1
Lund, NO1
Ebert-Petersen, F1
Liisberg, P1
Weihe, P1
Thybo, S1
Magnussen, P1
Hunziker, T1
Fehlmann, U1
Kummer, H1
Spengler, H1
Hoigné, R1
Salama, A1
Santoso, S1
Mueller-Eckhardt, C1
Hamm, H1
Aumiller, J1
Böhmer, R1
Missmahl, HP1
Füllbrandt, U1
Frenzel, H1
Miescher, PA1
Hendra, N1
Jarvik, LF1
Bloomfield, RJ1
Wilson, IJ1

Other Studies

10 other studies available for nomifensine and Allergy, Drug

ArticleYear
[Demonstration of drug-specific IgE and IgG antibodies using RIA: clinical importance as shown with nomifensin (Alival)].
    Schweizerische medizinische Wochenschrift, 1983, Dec-10, Volume: 113, Issue:49

    Topics: Alveolitis, Extrinsic Allergic; Anemia, Hemolytic; Antibody Formation; Antibody Specificity; Chemica

1983
[Drug fever during treatment with nomifensine (Alival)].
    Ugeskrift for laeger, 1981, May-24, Volume: 143, Issue:21

    Topics: Aged; Drug Hypersensitivity; Female; Fever; Humans; Isoquinolines; Male; Middle Aged; Nomifensine

1981
[Drug fever due to a new antidepressent, nomifensine (Alival)].
    Ugeskrift for laeger, 1981, May-24, Volume: 143, Issue:21

    Topics: Drug Hypersensitivity; Female; Fever; Humans; Isoquinolines; Male; Middle Aged; Nomifensine

1981
[Drug fever caused by the antidepressive agent nomifensine (Alival)].
    Schweizerische medizinische Wochenschrift, 1980, Sep-06, Volume: 110, Issue:36

    Topics: Aged; Drug Hypersensitivity; Fever; Humans; Isoquinolines; Lymphocyte Activation; Male; Middle Aged;

1980
Antigenic determinants responsible for the reactions of drug-dependent antibodies with blood cells.
    British journal of haematology, 1991, Volume: 78, Issue:4

    Topics: Anemia, Hemolytic; Antibodies; Cross Reactions; Drug Hypersensitivity; Epitopes; Erythrocytes; Human

1991
Alveolitis associated with nomifensine.
    Lancet (London, England), 1985, Jun-08, Volume: 1, Issue:8441

    Topics: Alveolitis, Extrinsic Allergic; Drug Hypersensitivity; Female; Humans; Isoquinolines; Middle Aged; N

1985
Nomifensine-induced allergic reactions.
    Lancet (London, England), 1985, Sep-07, Volume: 2, Issue:8454

    Topics: Acute Disease; Drug Hypersensitivity; Female; Humans; Isoquinolines; Lupus Erythematosus, Systemic;

1985
Merital withdrawn by manufacturer.
    The American journal of nursing, 1986, Volume: 86, Issue:5

    Topics: Anemia, Hemolytic; Drug Hypersensitivity; Drug Industry; Humans; Nomifensine

1986
Allergic reactions to nomifensine in the elderly.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:4

    Topics: Aged; Depressive Disorder; Drug Hypersensitivity; Humans; Nomifensine

1986
Nomifensine, acute hemolytic anemia, and renal failure.
    Annals of internal medicine, 1986, Volume: 105, Issue:5

    Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Drug Hypersensitivity; Female; Humans; Nomifensine

1986