nomifensine has been researched along with Aggression in 8 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of dopamine (DA) and nomifensine (NF) on muricide activity induced by thiamine deficiency were examined." | 7.67 | Suppressive effects of intraventricular injected dopamine and nomifensine on muricide induced by thiamine deficiency. ( Abe, Y; Kisara, K; Tadano, T; Yonezawa, A, 1987) |
| " Amphetamine and L-dopa pretreatment attenuated the increases in apomorphine-induced stereotypy and aggression in REMSD rats, but ECS selectively reduced apomorphine-induced aggression." | 7.67 | Reversal of the increase in apomorphine-induced stereotypy and aggression in REM sleep deprived rats by dopamine agonist pretreatments. ( Braz, S; Ferreira, TM; Silveira Filho, NG; Troncone, LR; Tufik, S, 1988) |
| "The effects of dopamine (DA) and nomifensine (NF) on muricide activity induced by thiamine deficiency were examined." | 3.67 | Suppressive effects of intraventricular injected dopamine and nomifensine on muricide induced by thiamine deficiency. ( Abe, Y; Kisara, K; Tadano, T; Yonezawa, A, 1987) |
| " Amphetamine and L-dopa pretreatment attenuated the increases in apomorphine-induced stereotypy and aggression in REMSD rats, but ECS selectively reduced apomorphine-induced aggression." | 3.67 | Reversal of the increase in apomorphine-induced stereotypy and aggression in REM sleep deprived rats by dopamine agonist pretreatments. ( Braz, S; Ferreira, TM; Silveira Filho, NG; Troncone, LR; Tufik, S, 1988) |
| "Nomifensine has demonstrated efficacy in several animal models that have been found to be predictive of clinical antidepressant activity, and has also been found to have a low potential for both cardiovascular and anticholinergic side effects." | 2.37 | Pharmacology of nomifensine: a review of animal studies. ( Fielding, S; Szewczak, MR, 1984) |
| " The effects observed indicate that the chronic administration of AD leads to the development of the increased responsiveness (or activation) of the noradrenergic system." | 1.26 | Atypical antidepressant drugs - psychopharmacological profile and mechanism of action. ( Maj, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kostowski, W | 1 |
| Valzelli, L | 1 |
| Kozak, W | 1 |
| Bernasconi, S | 1 |
| Fielding, S | 1 |
| Szewczak, MR | 1 |
| Maj, J | 1 |
| Koprowska, M | 1 |
| Romaniuk, A | 1 |
| Carlini, EA | 1 |
| Lindsey, CJ | 1 |
| Tufik, S | 2 |
| Al-Khatib, IM | 1 |
| Fujiwara, M | 1 |
| Iwasaki, K | 1 |
| Kataoka, Y | 1 |
| Ueki, S | 1 |
| Abe, Y | 1 |
| Tadano, T | 1 |
| Yonezawa, A | 1 |
| Kisara, K | 1 |
| Troncone, LR | 1 |
| Ferreira, TM | 1 |
| Braz, S | 1 |
| Silveira Filho, NG | 1 |
1 review available for nomifensine and Aggression
| Article | Year |
|---|---|
Pharmacology of nomifensine: a review of animal studies.
Topics: Acetylcholine; Adenylyl Cyclases; Aggression; Animals; Behavior, Animal; Brain Chemistry; Corpus Str | 1984 |
7 other studies available for nomifensine and Aggression
| Article | Year |
|---|---|
Activity of desipramine, fluoxetine and nomifensine on spontaneous and p-CPA-induced muricidal aggression.
Topics: Aggression; Animals; Antidepressive Agents; Desipramine; Fenclonine; Fluoxetine; Humans; Male; Nomif | 1984 |
Atypical antidepressant drugs - psychopharmacological profile and mechanism of action.
Topics: Aggression; Animals; Antidepressive Agents; Behavior, Animal; Drug Interactions; Humans; Iprindole; | 1982 |
Behavioral and biochemical alterations in median and dorsal raphe nuclei lesioned cats.
Topics: 5,7-Dihydroxytryptamine; Aggression; Animals; Behavior, Animal; Biogenic Monoamines; Carbachol; Cats | 1997 |
Cannabis, catecholamines, rapid eye movement sleep and aggressive behaviour.
Topics: Aggression; Animals; Apomorphine; Body Temperature; Brain Chemistry; Cannabis; Catecholamines; Human | 1977 |
The role of brain catecholamines in the exhibition of muricide induced by nucleus accumbens lesions and the effect of antidepressants in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Antidepressive Agents; Brain; Dopamine; Imipram | 1987 |
Suppressive effects of intraventricular injected dopamine and nomifensine on muricide induced by thiamine deficiency.
Topics: Aggression; Animals; Apomorphine; Dopamine; Hydroxydopamines; Injections, Intraventricular; Levodopa | 1987 |
Reversal of the increase in apomorphine-induced stereotypy and aggression in REM sleep deprived rats by dopamine agonist pretreatments.
Topics: Aggression; Amphetamine; Animals; Apomorphine; Bromocriptine; Carbidopa; Dopamine; Imipramine; Levod | 1988 |