Page last updated: 2024-11-01

nomifensine and Affective Disorders, Psychotic

nomifensine has been researched along with Affective Disorders, Psychotic in 2 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Affective Disorders, Psychotic: Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc.

Research Excerpts

ExcerptRelevanceReference
" Three double-blind placebo-controlled trials with nomifensine are reviewed; one in neurotic depression, one in psychotic depression and one in geriatric patients showing depressive symptoms."5.04Comparison of nomifensine and placebo. ( Taeuber, K, 1977)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Taeuber, K1
McClelland, HA1
Kerr, TA1
Little, JC1

Trials

2 trials available for nomifensine and Affective Disorders, Psychotic

ArticleYear
Comparison of nomifensine and placebo.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adjustment Disorders; Affective Disorders, Psychotic; Aged; Clinical Trials as Topic; Depression; Do

1977
A clinical comparison of nomifensine and amitriptyline.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adjustment Disorders; Adult; Affective Disorders, Psychotic; Amitriptyline; Clinical Trials as Topic

1977