Page last updated: 2024-11-01

nomifensine and Adenoma

nomifensine has been researched along with Adenoma in 24 studies

Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"A group of 17 hyperprolactinemic women was given 200 mg of nomifensine orally to evaluate its diagnostic potential to discriminate between tumors and nontumorous hyperprolactinemia."7.66Nomifensine test does not differentiate hyperprolactinemia associated with and without radiologic abnormalities in the sella turcica. ( Ablanedo, J; Canales, ES; Cano, C; Zárate, A, 1981)
"To verify the diagnostic capacity of some dynamic tests of the prolactin (Prl) secretion, the findings obtained by high-resolution computed tomography (CT) were compared with results obtained from tests using nomifensine (NOM) domperidone (DOM) and thyrotrophin-releasing hormone (TRH) in 72 patients with pathological hyperprolactinaemia."3.67Comparison between pituitary computed tomographic findings and tests of hypothalamo-pituitary function in 72 patients with hyperprolactinaemia. ( Bianchi, SD; Camanni, F; Ciccarelli, E; Gatti, G; Ghigo, E; Massara, F; Molinatti, GM; Müller, EE, 1986)
" Twenty-six women diagnosed by dynamic tests and radiologic examination as having PRL-secreting adenoma were treated surgically (15) or with bromocriptine (11) and their condition was evaluated one to three years later by TRH, nomifensine, and domperidone tests."3.67Prolactin secretion after surgery or bromocriptine treatment of prolactinoma. ( D'Antona, N; Danero, S; De Leo, V; Genazzani, AR; Petraglia, F; Sardelli, S, 1987)
"A group of 17 hyperprolactinemic women was given 200 mg of nomifensine orally to evaluate its diagnostic potential to discriminate between tumors and nontumorous hyperprolactinemia."3.66Nomifensine test does not differentiate hyperprolactinemia associated with and without radiologic abnormalities in the sella turcica. ( Ablanedo, J; Canales, ES; Cano, C; Zárate, A, 1981)
"Nomifensine has recently been proposed as a dynamic test to discriminate tumoral from functional hyperprolactinaemia."1.26Some critical considerations on the use of the nomifensine test in the hyperprolactinaemic syndrome. ( Aliffi, A; D'Agata, R; Gulizia, S; Mongioì, A; Vicari, E; Volpicelli, D, 1981)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199024 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ferrari, C2
Romussi, M1
Benco, R1
Rampini, P2
Mailland, F1
Camanni, F5
Ghigo, E2
Ciccarelli, E2
Massara, F4
Campagnoli, C1
Molinatti, G1
Müller, EE8
Cocchi, D4
Novelli, A1
Ganzetti, I1
De Leo, V5
Franchi, F1
Danero, S2
Ricci, MG1
La Marca, S2
Urbani, TM2
Pieroni, ML1
D'Antona, N2
Genazzani, AR6
Canales, ES1
Cano, C1
Ablanedo, J1
Zárate, A1
Murru, S2
De Gennes, JL1
Turpin, G1
Heshmati, HM1
Carayon, A1
Pontiroli, AE2
Loda, G1
Roggia, A1
Scagliola, P1
Falsetti, L2
Massafra, C1
De Leo, M1
Venturi, C1
Abraham, G1
Crosignani, PG1
Caldara, R1
Picciotti, MC1
Malinverni, A1
Barattini, B1
Telloli, P1
Molinatti, GM3
Moriondo, P1
Travaglini, P1
Nissim, M1
Faglia, G1
D'Agata, R1
Aliffi, A1
Vicari, E1
Volpicelli, D1
Mongioì, A1
Gulizia, S1
Kamoi, K1
Tchuchida, I1
Sato, H1
Tanaka, R1
Ishiguro, T1
Kaneko, K1
Iwasaki, Y1
Shibata, A1
Gullo, D1
Carmina, E1
Mogavero, G1
Perino, A1
Venezia, R1
Genazzani, A1
Takeda, R1
Minagawa, F1
Nakabayashi, H1
Bianchi, SD1
Gatti, G1
Petraglia, F1
Sardelli, S1
Barbarino, A1
De Marinis, L1
Mancini, A1
Menini, E1
D'Amico, C1
Passeri, M1
Sambo, P1
Anile, C1
Maira, G1
Peñalva, A1
Torpia, R1
Rossi, GL1

Reviews

1 review available for nomifensine and Adenoma

ArticleYear
[Differential diagnosis of hyperprolactinemia].
    Nihon rinsho. Japanese journal of clinical medicine, 1986, Volume: 44, Issue:3

    Topics: Adenoma; Bromocriptine; Diagnosis, Differential; Humans; Hyperprolactinemia; Levodopa; Nomifensine;

1986

Other Studies

23 other studies available for nomifensine and Adenoma

ArticleYear
Effect of dihydroergocristine administration on serum prolactin and growth hormone levels in normal, hyperprolactinaemic, and acromegalic subjects: further evidence for pituitary dopamine deficiency in these conditions.
    Acta endocrinologica, 1983, Volume: 103, Issue:1

    Topics: Acromegaly; Adenoma; Adolescent; Adult; Amenorrhea; Dihydroergotoxine; Dopamine; Female; Growth Horm

1983
Defective regulation of prolactin secretion after successful removal of prolactinomas.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:6

    Topics: Adenoma; Adult; Domperidone; Female; Humans; Male; Nomifensine; Pituitary Neoplasms; Pregnancy; Prol

1983
In vivo supersensitivity of the anterior pituitary of old female rats to dopaminergic inhibition of prolactin secretion.
    Gerontology, 1984, Volume: 30, Issue:6

    Topics: Adenoma; Animals; Bromocriptine; Dopamine Antagonists; Female; Isoquinolines; Kinetics; Nomifensine;

1984
[Various aspects of dopaminergic function in patients with prolactin-secreting hypophyseal adenoma].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Dec-30, Volume: 59, Issue:12

    Topics: Adenoma; Adult; Amenorrhea; Carbidopa; Dopamine; Female; Humans; Levodopa; Nomifensine; Pituitary Ne

1983
Nomifensine test does not differentiate hyperprolactinemia associated with and without radiologic abnormalities in the sella turcica.
    Hormone research, 1981, Volume: 15, Issue:4

    Topics: Adenoma; Adult; Diagnosis, Differential; Female; Humans; Hyperprolactinemia; Nomifensine; Pituitary

1981
Dynamic tests of prolactin secretion in hyperprolactinemic states: carbidopa-L-dopa and indirectly acting dopamine agonists.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:2

    Topics: Adenoma; Adult; Carbidopa; Dopamine; Female; Humans; Kinetics; Levodopa; Methylphenidate; Nomifensin

1982
[Progress in the hormonal detection of pituitary prolactin adenoma].
    Annales de medecine interne, 1982, Volume: 133, Issue:1

    Topics: Adenoma; Bromocriptine; Domperidone; Humans; Metoclopramide; Nomifensine; Pituitary Neoplasms; Prola

1982
Benserazide and nomifensine in the diagnosis of prolactin-secreting pituitary adenomas.
    Acta endocrinologica, 1982, Volume: 101, Issue:2

    Topics: Adenoma; Benserazide; Female; Humans; Hydrazines; Isoquinolines; Nomifensine; Pituitary Neoplasms; P

1982
[Indirect dopamine agonists and direct dopamine antagonists in the diagnosis of hyperprolactinemia].
    Bollettino della Societa italiana di biologia sperimentale, 1982, Aug-30, Volume: 58, Issue:16

    Topics: Adenoma; Adult; Domperidone; False Negative Reactions; False Positive Reactions; Female; Humans; Iso

1982
Use of bromocriptine as a diagnostic and therapeutic tool in hyperprolactinemic states.
    Progress in clinical and biological research, 1982, Volume: 112 Pt A

    Topics: Adenoma; Adolescent; Adult; Amenorrhea; Bromocriptine; Child; Female; Galactorrhea; Humans; Lactatio

1982
Failure of nomifensine administration to discriminate between tumorous and nontumorous hyperprolactinemia.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:1

    Topics: Adenoma; Adolescent; Adult; Amenorrhea; Diagnosis, Differential; Female; Galactorrhea; Humans; Isoqu

1980
Tests of prolactin secretion in the diagnosis of hyperprolactinemic states: nomifensine and domperidone.
    Fertility and sterility, 1981, Volume: 35, Issue:2

    Topics: Adenoma; Adult; Benzimidazoles; Domperidone; Female; Humans; Isoquinolines; Male; Menstruation; Midd

1981
Evaluation of two inhibitory tests (nomifensine and L-dopa + carbidopa) for the diagnosis of hyperprolactinaemic states.
    Clinical endocrinology, 1980, Volume: 13, Issue:6

    Topics: Adenoma; Adolescent; Adult; Carbidopa; Diagnosis, Differential; Female; Humans; Isoquinolines; Levod

1980
Some critical considerations on the use of the nomifensine test in the hyperprolactinaemic syndrome.
    Hormone research, 1981, Volume: 14, Issue:3

    Topics: Adenoma; Adolescent; Adult; Clinical Laboratory Techniques; Diagnosis, Differential; Female; Humans;

1981
Comparison of the responses in the nomifensine test with hyperprolactinemia due to prolactin-secreting pituitary tumors and nonprolactin-secreting hypothalamic tumors.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:6

    Topics: Adenoma; Adult; Female; Humans; Hypothalamic Neoplasms; Isoquinolines; Male; Middle Aged; Nomifensin

1981
Nomifensine in the diagnosis of hyperprolactinemia.
    Acta Europaea fertilitatis, 1981, Volume: 12, Issue:4

    Topics: Adenoma; Adolescent; Adult; Female; Humans; Isoquinolines; Nomifensine; Pituitary Neoplasms; Prolact

1981
Biochemical diagnosis of prolactinoma.
    Lancet (London, England), 1979, Aug-04, Volume: 2, Issue:8136

    Topics: Adenoma; Female; Humans; Nomifensine; Paraneoplastic Endocrine Syndromes; Pituitary Gland, Anterior;

1979
Nomifensine: diagnostic test in hyperprolactinemic states.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:6

    Topics: Adenoma; Female; Humans; Isoquinolines; Lactation; Nomifensine; Pituitary Neoplasms; Postpartum Peri

1978
Comparison between pituitary computed tomographic findings and tests of hypothalamo-pituitary function in 72 patients with hyperprolactinaemia.
    Acta endocrinologica, 1986, Volume: 112, Issue:1

    Topics: Adenoma; Adolescent; Adult; Domperidone; Female; Humans; Hyperprolactinemia; Hypothalamo-Hypophyseal

1986
Prolactin secretion after surgery or bromocriptine treatment of prolactinoma.
    Obstetrics and gynecology, 1987, Volume: 69, Issue:1

    Topics: Adenoma; Adult; Bromocriptine; Domperidone; Female; Humans; Hypophysectomy; Nomifensine; Pituitary N

1987
Prolactin dynamics in patients with non-secretin tumours of the hypothalamic-pituitary region.
    Acta endocrinologica, 1985, Volume: 110, Issue:1

    Topics: Adenoma; Adenoma, Chromophobe; Adolescent; Adult; Craniopharyngioma; Female; Follicle Stimulating Ho

1985
Persistence of a defective tuberoinfundibular dopaminergic function in rats after long-term removal of oestrogen treatment. An in vivo study.
    Acta endocrinologica, 1985, Volume: 109, Issue:3

    Topics: Adenoma; Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Domperidone; Estradiol; Female; Hypothalam

1985
More on nomifensine.
    Journal of endocrinological investigation, 1985, Volume: 8, Issue:5

    Topics: Adenoma; Female; Humans; Hyperprolactinemia; Nomifensine; Pituitary Neoplasms

1985