nomifensine has been researched along with Acute Kidney Failure in 12 studies
Nomifensine: An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
nomifensine : An N-methylated tetrahydroisoquinoline carrying phenyl and amino substituents at positions C-4 and C-8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nomifensine was withdrawn from markets worldwide because of reports of serious hypersensitivity reactions, especially hemolytic anemia, and marketing of bupropion in the United States was delayed after seizures occurred in bulimic patients in clinical trials." | 2.37 | Adverse reactions to five new antidepressants. ( Hayes, PE; Kristoff, CA, 1986) |
| "Nomifensine is a widely used antidepressant agent with few side-effects but haemolytic anaemia with acute renal failure has been reported with both intermittent therapeutic dosage and self-inflicted overdose." | 1.27 | Intravascular haemolysis and acute renal failure induced by nomifensine. ( Briggs, JD; Dominiczak, AF; Fulton, JD; Junor, BJ; Lucie, NP, 1986) |
| "A case of acute renal failure after an overdose of nomifensine is reported in a man who had evidence of chronic intravascular haemolysis on presentation, but not of acute haemolysis." | 1.27 | Acute renal failure without acute intravascular haemolysis after nomifensine overdosage. ( Ferner, RE; Skinner, R, 1986) |
| "Nomifensine is an antidepressant drug (widely used in Europe, but not yet available in the United States), which has been linked to intravascular hemolysis." | 1.27 | The role of metabolite-specific antibodies in nomifensine-dependent immune hemolytic anemia. ( Mueller-Eckhardt, C; Salama, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eckstein, R | 1 |
| Riess, H | 1 |
| Sauer, H | 1 |
| Mempel, W | 1 |
| Prescott, LF | 1 |
| Illingworth, RN | 1 |
| Critchley, JA | 1 |
| Frazer, I | 1 |
| Stirling, ML | 1 |
| Bournerias, F | 1 |
| Nabibi, B | 1 |
| Hayes, PE | 1 |
| Kristoff, CA | 1 |
| Fulton, JD | 1 |
| Briggs, JD | 1 |
| Dominiczak, AF | 1 |
| Junor, BJ | 1 |
| Lucie, NP | 1 |
| Oberhofer, R | 2 |
| Amor, H | 2 |
| Prinoth, O | 2 |
| Skinner, R | 1 |
| Ferner, RE | 1 |
| Mueller-Eckhardt, C | 2 |
| Salama, A | 2 |
| Bloomfield, RJ | 1 |
| Wilson, IJ | 1 |
| Köber, M | 1 |
| Reinhold, HM | 1 |
| Schneider, H | 1 |
1 review available for nomifensine and Acute Kidney Failure
| Article | Year |
|---|---|
Adverse reactions to five new antidepressants.
Topics: Acute Kidney Injury; Amoxapine; Animals; Antidepressive Agents; Bupropion; Cardiovascular Diseases; | 1986 |
11 other studies available for nomifensine and Acute Kidney Failure
| Article | Year |
|---|---|
[Nomifensin-induced immune haemolytic anaemias (author's transl)].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic, Autoimmune; Coombs Test; Depressive Disorder; Humans; | 1981 |
Acute haemolysis and renal failure after nomifensine overdosage.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Autoantibodies; Female; Humans; Isoquinolines; Kidney | 1980 |
Nomifensine-induced immune haemolytic anaemia and impaired renal function.
Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Female; Humans; Isoquinolines; Middle Aged; Nomi | 1979 |
Intravascular haemolysis and acute renal failure induced by nomifensine.
Topics: Acute Kidney Injury; Anemia, Hemolytic, Autoimmune; Depression; Female; Humans; Middle Aged; Nomifen | 1986 |
[Hemolytic anemia with kidney failure after nomifensine].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic, Autoimmune; Female; Humans; Nomifensine | 1986 |
Acute renal failure without acute intravascular haemolysis after nomifensine overdosage.
Topics: Acute Kidney Injury; Hemolysis; Humans; Male; Middle Aged; Nomifensine | 1986 |
[Hemolytic anemia and renal failure caused by nomifensine].
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Female; Humans; Male; | 1986 |
Nomifensine, acute hemolytic anemia, and renal failure.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Drug Hypersensitivity; Female; Humans; Nomifensine | 1986 |
[Hemolytic anemia and renal insufficiency caused by nomifensine. Description of a case].
Topics: Acute Kidney Injury; Anemia, Hemolytic; Female; Humans; Middle Aged; Nomifensine | 1986 |
[Nomifensine-induced hemolysis with acute renal failure].
Topics: Acute Kidney Injury; Adjustment Disorders; Adult; Anemia, Hemolytic; Female; Hemolysis; Humans; Nomi | 1986 |
The role of metabolite-specific antibodies in nomifensine-dependent immune hemolytic anemia.
Topics: Acute Disease; Acute Kidney Injury; Adult; Aged; Anemia, Hemolytic; Antibodies; Antibody Specificity | 1985 |