nocodazole has been researched along with Tetraploid in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We further show that MPS1-inhibited tetraploid cells promote mitotic catastrophe executed by the intrinsic pathway of apoptosis, as indicated by the loss of mitochondrial potential, the release of the pro-apoptotic cytochrome c from mitochondria, and the activation of caspases." | 1.43 | Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition. ( Abrieu, A; Castedo, M; Chibon, F; Jemaà, M; Kroemer, G; Lissa, D; Lledo, G; Manic, G; Morin, N; Reynes, C; Sistigu, A; Vitale, I, 2016) |
| "In contrast, tetraploid metaphases were found following pharmacological inhibition of Chk1 kinase, suggesting the involvement of the ATR/Chk1 pathway in the G2 arrest of binucleated cells." | 1.43 | Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication. ( Ascenzi, S; Cundari, E; De Santis Puzzonia, M; Degrassi, F; Gonzalez, L, 2016) |
| "Unexpectedly, tetraploidization is also under the control of a cell-extrinsic mechanism determined by the immune system." | 1.39 | Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy. ( Castedo, M; Galluzzi, L; Kroemer, G; Senovilla, L, 2013) |
| "Colon organoids generated from tetraploid Tp53 (-/-) cells exhibit a close-to-normal morphology as compared to their diploid Tp53 (-/-) counterparts, yet the colonocytes constituting these organoids are characterized by an increased cell size and an elevated expression of the immunostimulatory protein calreticulin on the cell surface." | 1.39 | Immunosurveillance against tetraploidization-induced colon tumorigenesis. ( Boilève, A; Castedo, M; Clevers, H; Galluzzi, L; Kroemer, G; Lissa, D; Martins, I; Métivier, D; Senovilla, L; van den Brink, S; Vitale, I, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Senovilla, L | 2 |
| Galluzzi, L | 2 |
| Castedo, M | 3 |
| Kroemer, G | 3 |
| Jemaà, M | 1 |
| Manic, G | 1 |
| Lledo, G | 1 |
| Lissa, D | 2 |
| Reynes, C | 1 |
| Morin, N | 1 |
| Chibon, F | 1 |
| Sistigu, A | 1 |
| Vitale, I | 2 |
| Abrieu, A | 1 |
| De Santis Puzzonia, M | 1 |
| Gonzalez, L | 1 |
| Ascenzi, S | 1 |
| Cundari, E | 1 |
| Degrassi, F | 1 |
| Boilève, A | 1 |
| Martins, I | 1 |
| Métivier, D | 1 |
| van den Brink, S | 1 |
| Clevers, H | 1 |
4 other studies available for nocodazole and Tetraploid
| Article | Year |
|---|---|
Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy.
Topics: Animals; Calreticulin; Cell Cycle; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA; End | 2013 |
Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.
Topics: Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Diploidy; HCT116 Cells; Humans; Imm | 2016 |
Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication.
Topics: Ataxia Telangiectasia Mutated Proteins; Camptothecin; Cell Line; Cell Proliferation; Cellular Senesc | 2016 |
Immunosurveillance against tetraploidization-induced colon tumorigenesis.
Topics: Animals; Antineoplastic Agents; Calreticulin; Cell Transformation, Neoplastic; Colon; Colonic Neopla | 2013 |