Page last updated: 2024-10-31

nocodazole and Spastic Paraplegia, Hereditary

nocodazole has been researched along with Spastic Paraplegia, Hereditary in 2 studies

Spastic Paraplegia, Hereditary: A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Solowska, JM1
D'Rozario, M1
Jean, DC1
Davidson, MW1
Marenda, DR1
Baas, PW1
Fassier, C1
Tarrade, A1
Peris, L1
Courageot, S1
Mailly, P1
Dalard, C1
Delga, S1
Roblot, N1
Lefèvre, J1
Job, D1
Hazan, J1
Curmi, PA1
Melki, J1

Other Studies

2 other studies available for nocodazole and Spastic Paraplegia, Hereditary

ArticleYear
Pathogenic mutation of spastin has gain-of-function effects on microtubule dynamics.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Jan-29, Volume: 34, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Animals, Genetically Modified; Cells, Cultured; Cysteine; Diseas

2014
Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice.
    Disease models & mechanisms, 2013, Volume: 6, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Axonal Transport; Axons; Cells, Cultured; Cerebral Cortex; Disea

2013