Page last updated: 2024-10-31

nocodazole and Poliomyelitis

nocodazole has been researched along with Poliomyelitis in 2 studies

Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)

Research Excerpts

ExcerptRelevanceReference
"Pre-treatment with nocodazole prevents complete fragmentation, indicating that microtubules are required for poliovirus-induced Golgi dispersion."1.34Poliovirus infection blocks ERGIC-to-Golgi trafficking and induces microtubule-dependent disruption of the Golgi complex. ( Andino, R; Beske, O; Kirkegaard, K; Reichelt, M; Taylor, MP, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campagnola, G1
Gong, P1
Peersen, OB1
Beske, O1
Reichelt, M1
Taylor, MP1
Kirkegaard, K1
Andino, R1

Other Studies

2 other studies available for nocodazole and Poliomyelitis

ArticleYear
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
    Antiviral research, 2011, Volume: 91, Issue:3

    Topics: Allosteric Regulation; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; F

2011
Poliovirus infection blocks ERGIC-to-Golgi trafficking and induces microtubule-dependent disruption of the Golgi complex.
    Journal of cell science, 2007, Sep-15, Volume: 120, Issue:Pt 18

    Topics: Animals; Antineoplastic Agents; Chlorocebus aethiops; COS Cells; Endoplasmic Reticulum; Golgi Appara

2007