Page last updated: 2024-10-31

nocodazole and Neoplasms

nocodazole has been researched along with Neoplasms in 44 studies

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Currently, cancer and its progression to metastasis result in a large number of deaths."2.61Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues. ( de Lima Ferreira, LP; de Melo Rêgo, MJB; de Moraes Gomes, PAT; de Siqueira, LRP; Leite, ACL, 2019)
"Anticancer agents are critical for the cancer treatment, but side effects and the drug resistance associated with the currently used anticancer agents create an urgent need to explore novel drugs with low side effects and high efficacy."2.611,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships. ( Liu, Y; Xu, Z; Zhao, SJ, 2019)
"Hybrid anticancer drugs are of great therapeutic interests since they can potentially overcome most of the pharmacokinetic drawbacks encountered with conventional anticancer drugs."2.55Recent advances (2015-2016) in anticancer hybrids. ( Kerru, N; Koorbanally, N; Kumar, V; Raj, R; Singh, P, 2017)
"MTAs demonstrate anticancer activity either as microtubule-stabilizing agents (paclitaxel) or microtubule-destabilizing agents (nocodazole)."1.91Not all benzimidazole derivatives are microtubule destabilizing agents. ( Kim, T; Nimse, SB; Park, SJ; Song, IH; Song, KS; Yeom, GS, 2023)
"Chemotherapy and targeted agent anti-cancer efficacy is largely dependent on the proliferative state of tumours, as exemplified by agents that target DNA synthesis/replication or mitosis."1.62Quantifying cell cycle-dependent drug sensitivities in cancer using a high throughput synchronisation and screening approach. ( Carnevalli, LS; Dunlop, CR; Fernández, SBQ; Jodrell, DI; Johnson, TI; Kottmann, D; Lau, A; Minteer, CJ; Richards, FM; Wallez, Y, 2021)
"We further show that MPS1-inhibited tetraploid cells promote mitotic catastrophe executed by the intrinsic pathway of apoptosis, as indicated by the loss of mitochondrial potential, the release of the pro-apoptotic cytochrome c from mitochondria, and the activation of caspases."1.43Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition. ( Abrieu, A; Castedo, M; Chibon, F; Jemaà, M; Kroemer, G; Lissa, D; Lledo, G; Manic, G; Morin, N; Reynes, C; Sistigu, A; Vitale, I, 2016)
"Noscapine has since been discovered to arrest cells at mitosis, albeit with moderately weak activity."1.42Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents. ( Capuano, B; DeBono, A; Scammells, PJ, 2015)
"Unexpectedly, tetraploidization is also under the control of a cell-extrinsic mechanism determined by the immune system."1.39Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy. ( Castedo, M; Galluzzi, L; Kroemer, G; Senovilla, L, 2013)
"Treatment of nocodazole-synchronized cells with JNJ-7706621 was able to override mitotic arrest by preventing spindle checkpoint signaling, resulting in failure of chromosome alignment and segregation."1.38Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases. ( Hara, A; Kawai, G; Kimura, M; Matsuhashi, A; Nagano, A; Ohno, T; Okano, Y; Saio, M; Saitou, M; Shimizu, K; Takigami, I; Yamada, K, 2012)
"However, polyploidy may also render cancer cells more vulnerable to chemotherapy."1.36Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy. ( Deo, D; Heimbrook, DC; Higgins, B; Kolinsky, K; Liu, JJ; Tovar, C; Vassilev, LT, 2010)
"Quercetin is a flavonoid with anticancer properties."1.36The flavonoid quercetin transiently inhibits the activity of taxol and nocodazole through interference with the cell cycle. ( Fadlalla, K; Samuel, T; Turner, T; Yehualaeshet, TE, 2010)
"Many cancer-treating compounds used in chemotherapies, the so-called antimitotics, target the mitotic spindle."1.36Adapt or die: how eukaryotic cells respond to prolonged activation of the spindle assembly checkpoint. ( Galati, E; Piatti, S; Rossio, V, 2010)
"When cancer cells spread away from the primary tumor, they often follow the trajectories of lymphatic vessels, nerves, white matter tracts, or other heterogeneous structures in tissues."1.35Spontaneous migration of cancer cells under conditions of mechanical confinement. ( Irimia, D; Toner, M, 2009)
"Upon nocodazole treatment, GNE redistributes to the cytoplasm suggesting that GNE may act as a nucleocytoplasmic shuttling protein."1.33Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells. ( Amsili, S; Argov, Z; Hinderlich, S; Horstkorte, R; Krause, S; Lochmüller, H; Mitrani-Rosenbaum, S; Wiendl, H, 2005)
"Tetraploidy can result in cancer-associated aneuploidy."1.33Apoptosis regulation in tetraploid cancer cells. ( Casares, N; Castedo, M; Coquelle, A; Dessen, P; Garrido, C; Kauffmann, A; Kroemer, G; Lazar, V; Modjtahedi, N; Mouhamad, S; Pequignot, MO; Schmitt, E; Vainchenker, W; Valent, A; Vitale, I; Vivet, S; Zitvogel, L, 2006)
"In most colorectal cancers, and probably in many other cancer types, a chromosomal instability (CIN) leading to an abnormal chromosome number (aneuploidy) is observed."1.30Mutations of mitotic checkpoint genes in human cancers. ( Cahill, DP; Kinzler, KW; Lengauer, C; Markowitz, SD; Riggins, GJ; Vogelstein, B; Willson, JK; Yu, J, 1998)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (4.55)18.2507
2000's12 (27.27)29.6817
2010's27 (61.36)24.3611
2020's3 (6.82)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Kamal, A1
Reddy, MK1
Shaik, TB1
Srikanth, YV1
Reddy, VS1
Kumar, GB1
Kalivendi, SV1
Reddy, MV1
Mallireddigari, MR1
Pallela, VR1
Cosenza, SC1
Billa, VK1
Akula, B1
Subbaiah, DR1
Bharathi, EV1
Padgaonkar, A1
Lv, H1
Gallo, JM1
Reddy, EP1
DeBono, A1
Capuano, B1
Scammells, PJ1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Srivastava, V1
Lee, H2
Banu, S1
Bollu, R1
Bantu, R1
Nagarapu, L1
Polepalli, S1
Jain, N1
Vangala, R1
Manga, V1
Kerru, N1
Singh, P1
Koorbanally, N1
Raj, R1
Kumar, V1
de Siqueira, LRP1
de Moraes Gomes, PAT1
de Lima Ferreira, LP1
de Melo Rêgo, MJB1
Leite, ACL1
Lin, MS1
Hong, TM1
Chou, TH1
Yang, SC1
Chung, WC1
Weng, CW1
Tsai, ML1
Cheng, TR1
Chen, JJW1
Lee, TC1
Wong, CH1
Chein, RJ1
Yang, PC1
Xu, Z1
Zhao, SJ1
Liu, Y1
Song, IH1
Park, SJ1
Yeom, GS1
Song, KS1
Kim, T1
Nimse, SB1
Marquis, C1
Fonseca, CL1
Queen, KA1
Wood, L1
Vandal, SE1
Malaby, HLH1
Clayton, JE1
Stumpff, J1
Johnson, TI1
Minteer, CJ1
Kottmann, D1
Dunlop, CR1
Fernández, SBQ1
Carnevalli, LS1
Wallez, Y1
Lau, A1
Richards, FM1
Jodrell, DI1
Marks, DH1
Thomas, R1
Chin, Y1
Shah, R1
Khoo, C1
Benezra, R1
DeHart, DN1
Lemasters, JJ2
Maldonado, EN2
Werwein, E1
Cibis, H1
Hess, D1
Klempnauer, KH1
Senovilla, L1
Galluzzi, L1
Castedo, M3
Kroemer, G3
Kuang, Y1
Long, MJ1
Zhou, J1
Shi, J1
Gao, Y1
Xu, C1
Hedstrom, L1
Xu, B1
Shuda, M1
Velásquez, C1
Cheng, E1
Cordek, DG1
Kwun, HJ1
Chang, Y1
Moore, PS1
Moore, P1
Viegas, J1
Galán-Cobo, A1
Ramírez-Lorca, R1
Serna, A1
Echevarría, M1
Jemaà, M1
Manic, G1
Lledo, G1
Lissa, D1
Reynes, C1
Morin, N1
Chibon, F1
Sistigu, A1
Vitale, I2
Abrieu, A1
Stuart, HC1
Jia, Z1
Messenberg, A1
Joshi, B1
Underhill, TM1
Moukhles, H1
Nabi, IR1
Li, M1
Fang, X1
Wei, Z1
York, JP1
Zhang, P1
Tsui, M1
Xie, T1
Orth, JD1
Carpenter, AE1
Rudnicki, S1
Kim, S1
Shamu, CE1
Mitchison, TJ1
Irimia, D1
Toner, M1
Tovar, C1
Higgins, B1
Deo, D1
Kolinsky, K1
Liu, JJ1
Heimbrook, DC1
Vassilev, LT1
Samuel, T1
Fadlalla, K1
Turner, T1
Yehualaeshet, TE1
Jeon, J1
Ryu, YS1
Jeong, JE1
Shin, S1
Zhang, T1
Kang, SW1
Hong, JH1
Hur, GM1
Rossio, V1
Galati, E1
Piatti, S1
Patnaik, J1
Mullins, MR1
Park, H1
Hong, S2
Matsuhashi, A1
Ohno, T1
Kimura, M1
Hara, A1
Saio, M1
Nagano, A1
Kawai, G1
Saitou, M1
Takigami, I1
Yamada, K1
Okano, Y1
Shimizu, K1
Lee, CG1
Park, GY1
Han, YK1
Lee, JH1
Chun, SH1
Park, HY1
Lim, KH1
Kim, EG1
Choi, YJ1
Yang, K1
Lee, CW1
Xu, K1
Ludueña, RF1
Krause, S1
Hinderlich, S1
Amsili, S1
Horstkorte, R1
Wiendl, H1
Argov, Z1
Mitrani-Rosenbaum, S1
Lochmüller, H1
Dowling, M1
Voong, KR2
Kim, M2
Keutmann, MK1
Harris, E1
Kao, GD2
Seeber, S1
Issinger, OG1
Holm, T1
Kristensen, LP1
Guerra, B1
Coquelle, A1
Vivet, S1
Kauffmann, A1
Dessen, P1
Pequignot, MO1
Casares, N1
Valent, A1
Mouhamad, S1
Schmitt, E1
Modjtahedi, N1
Vainchenker, W1
Zitvogel, L1
Lazar, V1
Garrido, C1
Liao, J1
Dowling, ML1
Parker, SE1
Wang, S1
El-Deiry, WS1
Cahill, DP1
Lengauer, C1
Yu, J1
Riggins, GJ1
Willson, JK1
Markowitz, SD1
Kinzler, KW1
Vogelstein, B1
Larsen, CJ1

Reviews

5 reviews available for nocodazole and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Recent advances (2015-2016) in anticancer hybrids.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents; Drug Design; Humans; Neoplasms; Structure-Activity Relationship

2017
Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    Topics: Animals; Antineoplastic Agents; Cell Cycle Proteins; Disease Progression; Drug Delivery Systems; Dru

2019
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Tria

2019
[The RASSF1 (Ras association domain family protein 1) gene. Category: tumor suppressor gene].
    Bulletin du cancer, 2005, Volume: 92, Issue:11

    Topics: Animals; Apoptosis; Cell Cycle; Chromosomes, Human, Pair 3; DNA Methylation; Drug Resistance; Epigen

2005

Other Studies

39 other studies available for nocodazole and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors.
    European journal of medicinal chemistry, 2012, Volume: 50

    Topics: Benzimidazoles; Blotting, Western; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor;

2012
Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
    Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Blood-Brain Barrier;

2013
Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Noscap

2015
Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents.
    Bioorganic & medicinal chemistry, 2015, Dec-15, Volume: 23, Issue:24

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Hu

2015
Design, synthesis and docking studies of novel 1,2-dihydro-4-hydroxy-2-oxoquinoline-3-carboxamide derivatives as a potential anti-proliferative agents.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Molecular Docking Simulation; N

2017
4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Cell Proliferation; Colchicine; Drug Resistance, Ne

2019
Not all benzimidazole derivatives are microtubule destabilizing agents.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 164

    Topics: Antineoplastic Agents; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays,

2023
Chromosomally unstable tumor cells specifically require KIF18A for proliferation.
    Nature communications, 2021, 02-22, Volume: 12, Issue:1

    Topics: Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Proliferation; Centrosome; Chromosomal In

2021
Quantifying cell cycle-dependent drug sensitivities in cancer using a high throughput synchronisation and screening approach.
    EBioMedicine, 2021, Volume: 68

    Topics: Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytid

2021
Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.
    Cell reports, 2017, 05-30, Volume: 19, Issue:9

    Topics: Animals; ATPases Associated with Diverse Cellular Activities; Base Sequence; Cell Cycle Checkpoints;

2017
Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells.
    SLAS discovery : advancing life sciences R & D, 2018, Volume: 23, Issue:1

    Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Energy Metabol

2018
Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization.
    Nucleic acids research, 2019, 01-10, Volume: 47, Issue:1

    Topics: Carcinogenesis; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinases; Gene Expression Regulatio

2019
Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy.
    Annals of the New York Academy of Sciences, 2013, Volume: 1284

    Topics: Animals; Calreticulin; Cell Cycle; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA; End

2013
Prion-like nanofibrils of small molecules (PriSM) selectively inhibit cancer cells by impeding cytoskeleton dynamics.
    The Journal of biological chemistry, 2014, Oct-17, Volume: 289, Issue:42

    Topics: Antineoplastic Agents; Apoptosis; Cytoskeleton; Endocytosis; Glioblastoma; HeLa Cells; Hep G2 Cells;

2014
CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, May-12, Volume: 112, Issue:19

    Topics: Adaptor Proteins, Signal Transducing; Antigens, Polyomavirus Transforming; CDC2 Protein Kinase; Cell

2015
QnAs with Patrick Moore.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, May-12, Volume: 112, Issue:19

    Topics: Cell Division; Herpesvirus 8, Human; Humans; Merkel cell polyomavirus; Mitosis; Neoplasms; Nocodazol

2015
Overexpression of AQP3 Modifies the Cell Cycle and the Proliferation Rate of Mammalian Cells in Culture.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Animals; Aquaporin 3; Cell Cycle Checkpoints; Cell Division; G2 Phase; Gene Expression Regulation, N

2015
Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition.
    Oncotarget, 2016, Jan-05, Volume: 7, Issue:1

    Topics: Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Diploidy; HCT116 Cells; Humans; Imm

2016
Localized Rho GTPase activation regulates RNA dynamics and compartmentalization in tumor cell protrusions.
    The Journal of biological chemistry, 2008, Dec-12, Volume: 283, Issue:50

    Topics: Animals; Antineoplastic Agents; Cell Line; Dogs; Enzyme Activation; Fluorescence Resonance Energy Tr

2008
Loss of spindle assembly checkpoint-mediated inhibition of Cdc20 promotes tumorigenesis in mice.
    The Journal of cell biology, 2009, Jun-15, Volume: 185, Issue:6

    Topics: Amino Acid Sequence; Aneuploidy; Animals; Cdc20 Proteins; Cell Cycle Proteins; Cells, Cultured; Chro

2009
An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor.
    PloS one, 2009, Oct-05, Volume: 4, Issue:10

    Topics: Genome, Human; Green Fluorescent Proteins; HeLa Cells; Humans; Image Processing, Computer-Assisted;

2009
Spontaneous migration of cancer cells under conditions of mechanical confinement.
    Integrative biology : quantitative biosciences from nano to macro, 2009, Volume: 1, Issue:8-9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Humans; Microfluidics; Microscopy, Phase-Con

2009
Small-molecule inducer of cancer cell polyploidy promotes apoptosis or senescence: Implications for therapy.
    Cell cycle (Georgetown, Tex.), 2010, Aug-15, Volume: 9, Issue:16

    Topics: Antineoplastic Agents; Apoptosis; Benzodiazepines; Cell Line, Tumor; Cellular Senescence; Humans; Mi

2010
The flavonoid quercetin transiently inhibits the activity of taxol and nocodazole through interference with the cell cycle.
    Nutrition and cancer, 2010, Volume: 62, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation;

2010
Disruption of microtubules sensitizes the DNA damage-induced apoptosis through inhibiting nuclear factor κB (NF-κB) DNA-binding activity.
    Journal of Korean medical science, 2010, Volume: 25, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Caspases; Cell Line; Colchicine; DNA; DNA Damage; D

2010
Adapt or die: how eukaryotic cells respond to prolonged activation of the spindle assembly checkpoint.
    Biochemical Society transactions, 2010, Volume: 38, Issue:6

    Topics: Adaptation, Physiological; Aneuploidy; Antimitotic Agents; Cell Cycle Proteins; Eukaryotic Cells; Fu

2010
Free tubulin modulates mitochondrial membrane potential in cancer cells.
    Cancer research, 2010, Dec-15, Volume: 70, Issue:24

    Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane; Colchic

2010
Nocodazole is a high-affinity ligand for the cancer-related kinases ABL, c-KIT, BRAF, and MEK.
    ChemMedChem, 2012, Jan-02, Volume: 7, Issue:1

    Topics: Antineoplastic Agents; Humans; Mitogen-Activated Protein Kinase Kinases; Models, Molecular; Neoplasm

2012
Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.
    Current cancer drug targets, 2012, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents; Aurora Kinase A; Aurora Kinase B; Aurora Kinases; Bone Neoplasms; Ce

2012
Roles of 14-3-3η in mitotic progression and its potential use as a therapeutic target for cancers.
    Oncogene, 2013, Mar-21, Volume: 32, Issue:12

    Topics: 14-3-3 Proteins; Aneuploidy; Apoptosis; Caspase 9; Cell Division; Forkhead Box Protein O3; Forkhead

2013
Characterization of nuclear betaII-tubulin in tumor cells: a possible novel target for taxol.
    Cell motility and the cytoskeleton, 2002, Volume: 53, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Nucleolus; Cell Nucleus; Colchicine; Dim

2002
Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells.
    Experimental cell research, 2005, Apr-01, Volume: 304, Issue:2

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Brefeldin A; Cell Compartmentation;

2005
Mitotic spindle checkpoint inactivation by trichostatin a defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents.
    Cancer biology & therapy, 2005, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Cell Cycle; Cell Cycle Proteins; Cell Survival; Centrosome; Drug Therapy, Com

2005
Validation of protein kinase CK2 as oncological target.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:4

    Topics: Apoptosis; Casein Kinase II; Catalytic Domain; Cell Transformation, Neoplastic; Flow Cytometry; HCT1

2005
Apoptosis regulation in tetraploid cancer cells.
    The EMBO journal, 2006, Jun-07, Volume: 25, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cisplatin;

2006
TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells.
    Cancer research, 2008, May-01, Volume: 68, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Drug Evaluation, Preclinical;

2008
Mutations of mitotic checkpoint genes in human cancers.
    Nature, 1998, Mar-19, Volume: 392, Issue:6673

    Topics: Amino Acid Sequence; Aneuploidy; Antineoplastic Agents; Cell Cycle; Cloning, Molecular; Colorectal N

1998
[Have they discovered the origins of aneuploidy in tumors?].
    Bulletin du cancer, 1998, Volume: 85, Issue:7

    Topics: Aneuploidy; Antineoplastic Agents; Humans; Microsatellite Repeats; Microtubules; Mitosis; Mitotic In

1998