Page last updated: 2024-10-31

nocodazole and Melanoma

nocodazole has been researched along with Melanoma in 7 studies

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"Nuclear iASPP is enriched in melanoma metastasis and associates with poor patient survival."1.39Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP. ( Baer, C; Breyssens, H; Brown, NR; Caballero, OL; Cebon, J; Endicott, J; Goding, CR; Hu, Y; John, T; Jones, EY; Kessler, BM; Knapp, S; Lu, M; Lu, X; Middleton, MR; Ratnayaka, I; Salter, V; Siebold, C; Sullivan, A; Sviderskaya, EV; Zhong, S, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Mahboobi, S1
Pongratz, H1
Hufsky, H1
Hockemeyer, J1
Frieser, M1
Lyssenko, A1
Paper, DH1
Bürgermeister, J1
Böhmer, FD1
Fiebig, HH1
Burger, AM1
Baasner, S1
Beckers, T1
Endo, Y1
Saeki, K1
Watanabe, M1
Miyajima-Magara, N1
Igarashi, M1
Mochizuki, M1
Nishimura, R1
Sugano, S1
Sasaki, N1
Nakagawa, T1
Lu, M1
Breyssens, H1
Salter, V1
Zhong, S1
Hu, Y1
Baer, C1
Ratnayaka, I1
Sullivan, A1
Brown, NR1
Endicott, J1
Knapp, S1
Kessler, BM1
Middleton, MR1
Siebold, C1
Jones, EY1
Sviderskaya, EV1
Cebon, J1
John, T1
Caballero, OL1
Goding, CR1
Lu, X1
Spangler, B1
Kappelmann, M1
Schittek, B1
Meierjohann, S1
Vardimon, L1
Bosserhoff, AK1
Kuphal, S1
Wang, Q1
Moyret-Lalle, C1
Couzon, F1
Surbiguet-Clippe, C1
Saurin, JC1
Lorca, T1
Navarro, C1
Puisieux, A1
Sjoberg, ER1
Chammas, R1
Ozawa, H1
Kawashima, I1
Khoo, KH1
Morris, HR1
Dell, A1
Tai, T1
Varki, A1
Fink-Puches, R1
Hofmann-Wellenhof, R1
Smolle, J1
Helige, C1
Kerl, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Decitabine and Arsenic Trioxide(ATO) in the Treatment of Myelodysplasic Syndrome[NCT03377725]Phase 30 participants (Actual)Interventional2018-03-20Withdrawn (stopped due to No patient was involved.)
Decitabine,Cytarabine(Ara-C) and Arsenic Trioxide(ATO) in the Treatment of Acute Myeloid Leukemia With p53 Mutations[NCT03381781]Phase 2100 participants (Anticipated)Interventional2018-03-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for nocodazole and Melanoma

ArticleYear
Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents.
    Journal of medicinal chemistry, 2001, Dec-20, Volume: 44, Issue:26

    Topics: Allantois; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Biopolymers; Cattle; Chorion; Dr

2001
Spindle assembly checkpoint competence in aneuploid canine malignant melanoma cell lines.
    Tissue & cell, 2020, Volume: 67

    Topics: Aneuploidy; Animals; Cell Cycle Proteins; Cell Line, Tumor; Chromatids; Dog Diseases; Dogs; Histones

2020
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
    Cancer cell, 2013, May-13, Volume: 23, Issue:5

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell

2013
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
    Cancer cell, 2013, May-13, Volume: 23, Issue:5

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell

2013
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
    Cancer cell, 2013, May-13, Volume: 23, Issue:5

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell

2013
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP.
    Cancer cell, 2013, May-13, Volume: 23, Issue:5

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Apoptosis; CDC2 Protein Kinase; Cell

2013
ETS-1/RhoC signaling regulates the transcription factor c-Jun in melanoma.
    International journal of cancer, 2012, Jun-15, Volume: 130, Issue:12

    Topics: Cadherins; Cell Line, Tumor; Cytoskeleton; Humans; Melanoma; Nocodazole; Promoter Regions, Genetic;

2012
Alterations of anaphase-promoting complex genes in human colon cancer cells.
    Oncogene, 2003, Mar-13, Volume: 22, Issue:10

    Topics: Anaphase-Promoting Complex-Cyclosome; Antineoplastic Agents; Apc3 Subunit, Anaphase-Promoting Comple

2003
Expression of de-N-acetyl-gangliosides in human melanoma cells is induced by genistein or nocodazole.
    The Journal of biological chemistry, 1995, Feb-17, Volume: 270, Issue:7

    Topics: Antibodies, Monoclonal; Benzoquinones; Cell Line; Chromatography, High Pressure Liquid; Chromatograp

1995
Cytoplasmic microtubules in two different mouse melanoma cell lines: a qualitative and quantitative analysis using confocal laser scanning microscopy and computer-assisted image analysis.
    Journal of cutaneous pathology, 1997, Volume: 24, Issue:6

    Topics: Animals; Female; Fluorescent Antibody Technique, Indirect; Image Processing, Computer-Assisted; Mela

1997