nocodazole has been researched along with Leukemia in 6 studies
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The proportions of aneuploid/polyploid versus euploid cells formed after treatment with spindle poisons like nocodazole are of course dependent on the relative survival of cells with numerical chromosome aberrations." | 7.70 | Induction of polyploidy and apoptosis after exposure to high concentrations of the spindle poison nocodazole. ( Cundari, E; Cunha, M; Decordier, I; Geleyns, K; Kirsch-Volders, M; Verdoodt, B, 1999) |
| "The proportions of aneuploid/polyploid versus euploid cells formed after treatment with spindle poisons like nocodazole are of course dependent on the relative survival of cells with numerical chromosome aberrations." | 3.70 | Induction of polyploidy and apoptosis after exposure to high concentrations of the spindle poison nocodazole. ( Cundari, E; Cunha, M; Decordier, I; Geleyns, K; Kirsch-Volders, M; Verdoodt, B, 1999) |
| "Nocodazole, a water insoluble antimitotic drug active on L1210 leukemia was incorporated into liposomes, to investigate whether this procedure could increase cellular uptake." | 3.66 | Nocodazole entrapped into liposomes: no more effect on human CFU-C than free nocodazole. ( Brassinne, C; Delforge, A; Hildebrand, J; Laduron, C; Loos, M; Mattelaer, M; Stryckmans, P, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| David, MD | 1 |
| Petit, D | 1 |
| Bertoglio, J | 1 |
| Matkovic, K | 1 |
| Lukinovic-Skudar, V | 1 |
| Banfic, H | 1 |
| Visnjic, D | 1 |
| Uematsu, Y | 1 |
| Kogo, Y | 1 |
| Ohishi, I | 1 |
| Loos, M | 1 |
| Delforge, A | 1 |
| Mattelaer, M | 1 |
| Laduron, C | 1 |
| Brassinne, C | 1 |
| Hildebrand, J | 1 |
| Stryckmans, P | 1 |
| van der Loo, B | 1 |
| Hong, Y | 1 |
| Hancock, V | 1 |
| Martin, JF | 1 |
| Erusalimsky, JD | 1 |
| Verdoodt, B | 1 |
| Decordier, I | 1 |
| Geleyns, K | 1 |
| Cunha, M | 1 |
| Cundari, E | 1 |
| Kirsch-Volders, M | 1 |
6 other studies available for nocodazole and Leukemia
| Article | Year |
|---|---|
The RhoGAP ARHGAP19 controls cytokinesis and chromosome segregation in T lymphocytes.
Topics: cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell Shape; Chromosome Seg | 2014 |
The activity of extracellular signal-regulated kinase is required during G2/M phase before metaphase-anaphase transition in synchronized leukemia cell lines.
Topics: Anaphase; Aphidicolin; Cell Cycle; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; G2 | 2009 |
Disassembly of actin filaments by botulinum C2 toxin and actin-filament-disrupting agents induces assembly of microtubules in human leukaemia cell lines.
Topics: Actin Cytoskeleton; Actins; Antineoplastic Agents; Botulinum Toxins; Cell Line, Tumor; Cell Polarity | 2007 |
Nocodazole entrapped into liposomes: no more effect on human CFU-C than free nocodazole.
Topics: Antineoplastic Agents; Benzimidazoles; Carbamates; Hematopoietic Stem Cells; Humans; Leukemia; Lipos | 1981 |
Antimicrotubule agents induce polyploidization of human leukaemic cell lines with megakaryocytic features.
Topics: Cell Division; Colchicine; Demecolcine; DNA; Flow Cytometry; Humans; Leukemia; Lumicolchicines; Mega | 1993 |
Induction of polyploidy and apoptosis after exposure to high concentrations of the spindle poison nocodazole.
Topics: Adult; Antineoplastic Agents; Apoptosis; Cell Survival; Cells, Cultured; Demecolcine; Dose-Response | 1999 |