nocodazole has been researched along with Huntington Disease in 2 studies
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Webb, JL | 1 |
| Ravikumar, B | 1 |
| Rubinsztein, DC | 1 |
| Hazeki, N | 1 |
| Nakamura, K | 1 |
| Goto, J | 1 |
| Kanazawa, I | 1 |
2 other studies available for nocodazole and Huntington Disease
| Article | Year |
|---|---|
Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases.
Topics: Animals; Autophagy; Chlorocebus aethiops; COS Cells; Humans; Huntington Disease; Inclusion Bodies; L | 2004 |
Rapid aggregate formation of the huntingtin N-terminal fragment carrying an expanded polyglutamine tract.
Topics: Animals; Blotting, Western; Cell Nucleus; COS Cells; Cycloheximide; Cytochalasin D; Cytoplasm; Exons | 1999 |