Page last updated: 2024-10-31

nocodazole and Glioma

nocodazole has been researched along with Glioma in 6 studies

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
" In this study, we examined mechanisms of hyperploid formation in glioma cells by treatment with nocodazole, which activates spindle assembly checkpoint by inhibiting microtubule polymerization."3.71Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines. ( Inagaki, M; Nitta, M; Saya, H; Tada, M; Tsuiki, H; Ushio, Y, 2001)
"The mechanisms of carbachol-induced muscarinic acetylcholine receptor (mAChR) down-regulation, and recovery following carbachol withdrawal, were studied in the neuroblastoma x glioma hybrid NG108-15 cell line by specific ligand binding assays."3.67Mechanism of agonist-induced down-regulation and subsequent recovery of muscarinic acetylcholine receptors in a clonal neuroblastoma x glioma hybrid cell line. ( Berman, JD; Middleton, W; Ray, P, 1989)
" Hydrocortisone, a glucocorticoid hormone, renders C6 rat glioma cells (clone ST1) sensitive to a block by colchicine or nocodazole (microtubule disrupters) at the G1 phase of the cell cycle."3.66Glucocorticoid hormone renders a rat glioma cell line sensitive to a G1 phase block by microtubule disrupting agents. ( Armelin, HA; Farias, SE, 1982)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamamoto, M1
Suzuki, SO1
Himeno, M1
Inoue, T1
Hiratsuka, M1
Osaki, M1
Yamada, H1
Kishimoto, I1
Yamaguchi, S1
Nakano, S1
Katoh, M1
Ito, H1
Oshimura, M1
Farias, SE1
Armelin, HA1
Tsuiki, H2
Nitta, M2
Tada, M1
Inagaki, M1
Ushio, Y2
Saya, H2
Arima, Y1
Harada, K1
Nishizaki, T1
Sasaki, K1
Mimori, T1
Ray, P1
Middleton, W1
Berman, JD1

Other Studies

6 other studies available for nocodazole and Glioma

ArticleYear
The effects of dynein inhibition on the autophagic pathway in glioma cells.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2010, Feb-01, Volume: 30, Issue:1

    Topics: Adenine; Amino Acids; Autophagy; Cell Line, Tumor; Dynactin Complex; Dyneins; Enzyme Inhibitors; Gli

2010
SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress.
    Oncogene, 2007, Feb-15, Volume: 26, Issue:7

    Topics: Cell Line, Tumor; Chromosomal Instability; Chromosomes, Human; Glioma; Histone Deacetylase Inhibitor

2007
Glucocorticoid hormone renders a rat glioma cell line sensitive to a G1 phase block by microtubule disrupting agents.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1982, Volume: 15, Issue:4-5

    Topics: Animals; Benzimidazoles; Cell Cycle; Cell Line; Colchicine; DNA, Neoplasm; Fibroblasts; Glioma; Grow

1982
Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines.
    Oncogene, 2001, Jan-25, Volume: 20, Issue:4

    Topics: CDC2 Protein Kinase; Glioma; Humans; Microtubules; Mitosis; Mitotic Index; Nocodazole; Polyploidy; S

2001
Hyperploidy induced by drugs that inhibit formation of microtubule promotes chromosome instability.
    Genes to cells : devoted to molecular & cellular mechanisms, 2002, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Chromosomes; Glioma; Humans; Microtubules; Nocodazole; Polyploidy; Tumor Cell

2002
Mechanism of agonist-induced down-regulation and subsequent recovery of muscarinic acetylcholine receptors in a clonal neuroblastoma x glioma hybrid cell line.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: Animals; Bacitracin; Benzimidazoles; Carbachol; Cell Membrane; Colchicine; Endocytosis; Glioma; Hybr

1989