Page last updated: 2024-10-31

nocodazole and Genetic Non-Disjunction

nocodazole has been researched along with Genetic Non-Disjunction in 10 studies

Research Excerpts

ExcerptRelevanceReference
" The aim was to visualize the events leading to aneuploidy directly during anaphase, analyse the induction of aneuploidy during this mitotic stage and compare the frequencies of chromosome malsegregation observed in ana-telophases with the estimated malsegregation obtained in binucleate cells after a short cytochalasin B treatment."3.70Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells. ( Cimini, D; Degrassi, F; Tanzarella, C, 1999)
"The possible risk of aneuploidy induction by the cancer chemotherapeutic drugs amsacrine (AMSA) and nocodazole (NOC) was investigated in male mice."1.35The chemotherapeutic agents nocodazole and amsacrine cause meiotic delay and non-disjunction in spermatocytes of mice. ( Adler, ID; Attia, SM; Badary, OA; Hamada, FM; Hrabé de Angelis, M, 2008)
"Aneuploidy is a key process in tumorigenesis."1.33FAT10 plays a role in the regulation of chromosomal stability. ( Chong, SS; Jeang, KT; Kan, A; Kon, OL; Lee, CG; Leong, SH; Ooi, LL; Ren, J, 2006)
"Nocodazole was administered either to maturing preovulatory oocytes or to normally ovulated eggs at one of the following stages: (1) the time of sperm entry, (2) early pronuclear stage, (3) pronuclear DNA synthesis, (4) prior to first cleavage division, (5) early 2-cell stage, or (6) prior to the second cleavage division."1.28Chromosome malsegregation and embryonic lethality induced by treatment of normally ovulated mouse oocytes with nocodazole. ( Bishop, JB; Cain, KT; Foxworth, LB; Generoso, WM; Hughes, LA; Katoh, M; Mitchell, TJ, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's2 (20.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yuan, J1
Xu, BZ1
Qi, ST1
Tong, JS1
Wei, L1
Li, M1
Ouyang, YC1
Hou, Y1
Schatten, H1
Sun, QY1
Holt, JE1
Lane, SI1
Jennings, P1
García-Higuera, I1
Moreno, S1
Jones, KT1
Ren, J1
Kan, A1
Leong, SH1
Ooi, LL1
Jeang, KT1
Chong, SS1
Kon, OL1
Lee, CG1
Attia, SM1
Badary, OA1
Hamada, FM1
Hrabé de Angelis, M1
Adler, ID1
Everett, CA1
Searle, JB1
Cimini, D1
Tanzarella, C1
Degrassi, F1
Eichenlaub-Ritter, U3
Boll, I2
Generoso, WM1
Katoh, M1
Cain, KT1
Hughes, LA1
Foxworth, LB1
Mitchell, TJ1
Bishop, JB1

Other Studies

10 other studies available for nocodazole and Genetic Non-Disjunction

ArticleYear
MAPK-activated protein kinase 2 is required for mouse meiotic spindle assembly and kinetochore-microtubule attachment.
    PloS one, 2010, Jun-28, Volume: 5, Issue:6

    Topics: Animals; Kinetochores; MAP Kinase Kinase 2; Meiosis; Mice; Microtubules; Nocodazole; Nondisjunction,

2010
APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing.
    Molecular biology of the cell, 2012, Volume: 23, Issue:20

    Topics: Animals; CDC2 Protein Kinase; Cdc20 Proteins; Cdh1 Proteins; Cell Cycle Proteins; Cyclin B1; Kinesin

2012
FAT10 plays a role in the regulation of chromosomal stability.
    The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16

    Topics: Aneuploidy; Apoptosis; Blotting, Western; Calcium-Binding Proteins; Cell Cycle; Cell Cycle Proteins;

2006
The chemotherapeutic agents nocodazole and amsacrine cause meiotic delay and non-disjunction in spermatocytes of mice.
    Mutation research, 2008, Mar-12, Volume: 651, Issue:1-2

    Topics: Amsacrine; Aneuploidy; Animals; Antineoplastic Agents; In Situ Hybridization, Fluorescence; Injectio

2008
Pattern and frequency of nocodazole induced meiotic nondisjunction in oocytes of mice carrying the 'tobacco mouse' metacentric Rb(16.17)7Bnr.
    Genetical research, 1995, Volume: 66, Issue:1

    Topics: Anaphase; Animals; Antineoplastic Agents; Cells, Cultured; Centromere; Chromosomes; Dose-Response Re

1995
Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells.
    Mutagenesis, 1999, Volume: 14, Issue:6

    Topics: Anaphase; Aneuploidy; Cell Nucleus; Cells, Cultured; Chromosomes, Human, Pair 11; Chromosomes, Human

1999
Nocodazole sensitivity, age-related aneuploidy, and alterations in the cell cycle during maturation of mouse oocytes.
    Cytogenetics and cell genetics, 1989, Volume: 52, Issue:3-4

    Topics: Aging; Aneuploidy; Animals; Cell Cycle; Chromosomes; Female; Mice; Mice, Inbred Strains; Nocodazole;

1989
The spindle of mammalian oocytes: alterations in morphology and progression through meiosis with maternal age.
    Progress in clinical and biological research, 1989, Volume: 311

    Topics: Animals; Benzimidazoles; Female; Fluorescent Antibody Technique; Humans; Maternal Age; Meiosis; Mice

1989
Age-related non-disjunction, spindle formation and progression through maturation of mammalian oocytes.
    Progress in clinical and biological research, 1989, Volume: 318

    Topics: Age Factors; Animals; Female; Fluorescent Antibody Technique; In Vitro Techniques; Meiosis; Mice; Mi

1989
Chromosome malsegregation and embryonic lethality induced by treatment of normally ovulated mouse oocytes with nocodazole.
    Mutation research, 1989, Volume: 210, Issue:2

    Topics: Aneuploidy; Animals; Benzimidazoles; Embryo Transfer; Female; Fetal Death; In Vitro Techniques; Meta

1989