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nocodazole and Colonic Neoplasms

nocodazole has been researched along with Colonic Neoplasms in 30 studies

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"Colon organoids generated from tetraploid Tp53 (-/-) cells exhibit a close-to-normal morphology as compared to their diploid Tp53 (-/-) counterparts, yet the colonocytes constituting these organoids are characterized by an increased cell size and an elevated expression of the immunostimulatory protein calreticulin on the cell surface."1.39Immunosurveillance against tetraploidization-induced colon tumorigenesis. ( Boilève, A; Castedo, M; Clevers, H; Galluzzi, L; Kroemer, G; Lissa, D; Martins, I; Métivier, D; Senovilla, L; van den Brink, S; Vitale, I, 2013)
"All the gastric and colonic cancer cell lines expressed p34cdc2 and showed its kinase activity at various levels."1.29Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas. ( Ayhan, A; Ito, H; Kitadai, Y; Nishimura, K; Tahara, E; Yasui, W; Yokozaki, H, 1993)
"Nocodazole was found to drastically retard both the direct transport of apical proteins from the Golgi apparatus and the indirect transport (transcytosis) from the basolateral membrane to the apical cell surface."1.28Microtubule perturbation retards both the direct and the indirect apical pathway but does not affect sorting of plasma membrane proteins in intestinal epithelial cells (Caco-2). ( Bucher, K; Hauri, HP; Matter, K, 1990)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (33.33)18.2507
2000's14 (46.67)29.6817
2010's5 (16.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Medellin, DC1
Zhou, Q1
Scott, R1
Hill, RM1
Frail, SK1
Dasari, R1
Ontiveros, SJ1
Pelly, SC1
van Otterlo, WA1
Betancourt, T1
Shuster, CB1
Hamel, E1
Bai, R1
LaBarbera, DV1
Rogelj, S1
Frolova, LV1
Kornienko, A1
Park, KS1
Schecterson, L1
Gumbiner, BM1
Ito, S1
Okuda, S1
Abe, M1
Fujimoto, M1
Onuki, T1
Nishimura, T1
Takeichi, M1
Bernard, D1
Mondesert, O1
Gomes, A1
Duthen, Y1
Lobjois, V1
Cussat-Blanc, S1
Ducommun, B1
Stolz, A1
Vogel, C1
Schneider, V1
Ertych, N1
Kienitz, A1
Yu, H1
Bastians, H1
Payne, CM1
Crowley-Skillicorn, C1
Bernstein, C1
Holubec, H1
Moyer, MP1
Bernstein, H1
Boilève, A1
Senovilla, L1
Vitale, I1
Lissa, D1
Martins, I1
Métivier, D1
van den Brink, S1
Clevers, H1
Galluzzi, L1
Castedo, M1
Kroemer, G1
Wang, YJ1
Jeng, JH1
Chen, RJ1
Tseng, H1
Chen, LC1
Liang, YC1
Lin, CH1
Chen, CH1
Chu, JS1
Ho, WL1
Ho, YS1
Zhang, H1
Shi, X1
Zhang, QJ1
Hampong, M1
Paddon, H1
Wahyuningsih, D1
Pelech, S2
Wang, Q1
Moyret-Lalle, C1
Couzon, F1
Surbiguet-Clippe, C1
Saurin, JC1
Lorca, T1
Navarro, C1
Puisieux, A1
Shin, HJ1
Baek, KH2
Jeon, AH1
Park, MT1
Lee, SJ1
Kang, CM1
Lee, HS1
Yoo, SH1
Chung, DH1
Sung, YC1
McKeon, F2
Lee, CW2
Quignon, F1
Rozier, L1
Lachages, AM1
Bieth, A1
Simili, M1
Debatisse, M1
Ha, GH1
Kim, HS1
Jeong, SJ1
Kim, CM1
Wang, JA1
Meyer, TF1
Rudel, T1
McCool, DJ1
Forstner, JF1
Forstner, GG1
Park, J1
Cartwright, CA1
Long, BH1
Fairchild, CR1
Yasui, W1
Ayhan, A1
Kitadai, Y1
Nishimura, K1
Yokozaki, H1
Ito, H1
Tahara, E1
Chazaud, B1
Muriel, MP1
Aubery, M1
Decastel, M1
Maksymowych, AB1
Simpson, LL1
Gupta, M1
Fan, S1
Zhan, Q1
Kohn, KW1
O'Connor, PM2
Pommier, Y1
Haier, J1
Nasralla, M1
Nicolson, GL1
Chen, XM1
LaRusso, NF1
Han, EK1
Tahir, SK1
Cherian, SP1
Collins, N1
Ng, SC1
Russo, P1
Ottoboni, C1
Crippa, A1
Riou, JF1
Tighe, A1
Johnson, VL1
Albertella, M1
Taylor, SS1
Andreassen, PR1
Lacroix, FB1
Lohez, OD1
Margolis, RL1
Sayed, M1
Wong, C1
Marotta, A1
Salh, B1
Viallard, V1
Castan, I1
Trocheris, V1
Lacombe, C1
Matter, K1
Bucher, K1
Hauri, HP1

Other Studies

30 other studies available for nocodazole and Colonic Neoplasms

ArticleYear
Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities.
    Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Colonic Neoplasms;

2016
Enhanced endothelial barrier function by monoclonal antibody activation of vascular endothelial cadherin.
    American journal of physiology. Heart and circulatory physiology, 2021, 04-01, Volume: 320, Issue:4

    Topics: Adherens Junctions; Antibodies, Monoclonal; Antigens, CD; Cadherins; Capillary Permeability; Cell Ad

2021
Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells.
    Nature communications, 2017, 11-28, Volume: 8, Issue:1

    Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Actomyosin; Adherens Junctions; Biomechani

2017
A checkpoint-oriented cell cycle simulation model.
    Cell cycle (Georgetown, Tex.), 2019, Volume: 18, Issue:8

    Topics: Cell Proliferation; Colonic Neoplasms; Computer Simulation; Eukaryotic Cells; G1 Phase Cell Cycle Ch

2019
Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
    Cancer research, 2009, May-01, Volume: 69, Issue:9

    Topics: Apoptosis; Aurora Kinase B; Aurora Kinases; Carbazoles; Chromosome Aberrations; Colonic Neoplasms; D

2009
Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis.
    Nutrition and cancer, 2010, Volume: 62, Issue:6

    Topics: Cell Line, Tumor; Colonic Neoplasms; Deoxycholic Acid; Genomic Instability; Humans; Hydrophobic and

2010
Immunosurveillance against tetraploidization-induced colon tumorigenesis.
    Cell cycle (Georgetown, Tex.), 2013, Feb-01, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Calreticulin; Cell Transformation, Neoplastic; Colon; Colonic Neopla

2013
Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice.
    Molecular carcinogenesis, 2002, Volume: 34, Issue:4

    Topics: Adenocarcinoma; Animals; Antifungal Agents; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Pro

2002
Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells.
    The Journal of biological chemistry, 2002, Nov-15, Volume: 277, Issue:46

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Arsenates; Blotting, Western; C

2002
Alterations of anaphase-promoting complex genes in human colon cancer cells.
    Oncogene, 2003, Mar-13, Volume: 22, Issue:10

    Topics: Anaphase-Promoting Complex-Cyclosome; Antineoplastic Agents; Apc3 Subunit, Anaphase-Promoting Comple

2003
Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability.
    Cancer cell, 2003, Volume: 4, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle Proteins; Chromosoma

2003
Sustained mitotic block elicits DNA breaks: one-step alteration of ploidy and chromosome integrity in mammalian cells.
    Oncogene, 2007, Jan-11, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Anaphase; Animals; Antineoplastic Agents; Cells, Cultured; Chromosomes; Colonic Neop

2007
p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation.
    Cancer research, 2007, Aug-01, Volume: 67, Issue:15

    Topics: Antineoplastic Agents; Cell Cycle; Chromosomal Instability; Colonic Neoplasms; Fluorescent Antibody

2007
Cytoskeleton and motor proteins are required for the transcytosis of Neisseria gonorrhoeae through polarized epithelial cells.
    International journal of medical microbiology : IJMM, 2008, Volume: 298, Issue:3-4

    Topics: Actins; Bacterial Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cytoskeletal Proteins; Dynei

2008
Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct.
    The Biochemical journal, 1995, Nov-15, Volume: 312 ( Pt 1)

    Topics: Adenocarcinoma; Biomarkers, Tumor; Calcimycin; Carbachol; Cell Size; Colchicine; Colonic Neoplasms;

1995
Src activity increases and Yes activity decreases during mitosis of human colon carcinoma cells.
    Molecular and cellular biology, 1995, Volume: 15, Issue:5

    Topics: Aphidicolin; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; DNA Polymerase II; G2 Phase; Humans; Mi

1995
Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase.
    Cancer research, 1994, Aug-15, Volume: 54, Issue:16

    Topics: Anaphase; Cell Cycle; Colonic Neoplasms; Drug Screening Assays, Antitumor; G1 Phase; Humans; Nocodaz

1994
Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas.
    International journal of cancer, 1993, Jan-02, Volume: 53, Issue:1

    Topics: Blotting, Western; CDC2 Protein Kinase; Cell Cycle; Colonic Neoplasms; Gastric Mucosa; HeLa Cells; H

1993
Organization of the endoplasmic reticulum-Golgi system is related to the state of enterocytic differentiation of human HT-29 cells.
    Differentiation; research in biological diversity, 1996, Volume: 60, Issue:3

    Topics: Antineoplastic Agents; Brefeldin A; Cell Differentiation; Cell Division; Cell Membrane; Colonic Neop

1996
Binding and transcytosis of botulinum neurotoxin by polarized human colon carcinoma cells.
    The Journal of biological chemistry, 1998, Aug-21, Volume: 273, Issue:34

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Botulinum Toxins; Botulinum Toxins, Type A; Br

1998
Inactivation of p53 increases the cytotoxicity of camptothecin in human colon HCT116 and breast MCF-7 cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Colonic Neoplasms

1997
Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: role of integrin expression and cytoskeletal components.
    British journal of cancer, 1999, Volume: 80, Issue:12

    Topics: Acrylamide; Antibodies; Cell Adhesion; Colchicine; Colonic Neoplasms; Cycloheximide; Cytochalasin D;

1999
Mechanisms of attachment and internalization of Cryptosporidium parvum to biliary and intestinal epithelial cells.
    Gastroenterology, 2000, Volume: 118, Issue:2

    Topics: Animals; Antigens, Tumor-Associated, Carbohydrate; Bile Ducts; Cattle; Cell Adhesion; Cell Line; Col

2000
Modulation of paclitaxel resistance by annexin IV in human cancer cell lines.
    British journal of cancer, 2000, Volume: 83, Issue:1

    Topics: Annexin A4; Blotting, Western; Colchicine; Colonic Neoplasms; DNA, Complementary; Drug Resistance, M

2000
RPR-115135, a new non peptidomimetic farnesyltransferase inhibitor, induces G0/G1 arrest only in serum starved cells.
    International journal of oncology, 2001, Volume: 18, Issue:4

    Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell S

2001
Aneuploid colon cancer cells have a robust spindle checkpoint.
    EMBO reports, 2001, Volume: 2, Issue:7

    Topics: Adenomatous Polyposis Coli Protein; Aneuploidy; Animals; Antineoplastic Agents; Cell Cycle; Chromoso

2001
Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells.
    Cancer research, 2001, Oct-15, Volume: 61, Issue:20

    Topics: 14-3-3 Proteins; Antineoplastic Agents; Biomarkers, Tumor; Colonic Neoplasms; Cyclin-Dependent Kinas

2001
Protein kinase CK2 is involved in G2 arrest and apoptosis following spindle damage in epithelial cells.
    Oncogene, 2001, Oct-25, Volume: 20, Issue:48

    Topics: Apoptosis; Casein Kinase II; Cell Line; Colonic Neoplasms; Cyclin B; Enzyme Activation; Enzyme Inhib

2001
Fate of exogenous and newly synthesized cholesterol in intestinal cell lines.
    The International journal of biochemistry, 1992, Volume: 24, Issue:8

    Topics: Adenocarcinoma; Carcinoma; Cell Differentiation; Cholesterol; Cholesterol Esters; Colonic Neoplasms;

1992
Microtubule perturbation retards both the direct and the indirect apical pathway but does not affect sorting of plasma membrane proteins in intestinal epithelial cells (Caco-2).
    The EMBO journal, 1990, Volume: 9, Issue:10

    Topics: Adenocarcinoma; Cell Line; Cell Membrane; Colonic Neoplasms; Endocytosis; Epithelium; Humans; Kineti

1990