nocodazole has been researched along with Colonic Neoplasms in 30 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
Excerpt | Relevance | Reference |
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"Colon organoids generated from tetraploid Tp53 (-/-) cells exhibit a close-to-normal morphology as compared to their diploid Tp53 (-/-) counterparts, yet the colonocytes constituting these organoids are characterized by an increased cell size and an elevated expression of the immunostimulatory protein calreticulin on the cell surface." | 1.39 | Immunosurveillance against tetraploidization-induced colon tumorigenesis. ( Boilève, A; Castedo, M; Clevers, H; Galluzzi, L; Kroemer, G; Lissa, D; Martins, I; Métivier, D; Senovilla, L; van den Brink, S; Vitale, I, 2013) |
"All the gastric and colonic cancer cell lines expressed p34cdc2 and showed its kinase activity at various levels." | 1.29 | Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas. ( Ayhan, A; Ito, H; Kitadai, Y; Nishimura, K; Tahara, E; Yasui, W; Yokozaki, H, 1993) |
"Nocodazole was found to drastically retard both the direct transport of apical proteins from the Golgi apparatus and the indirect transport (transcytosis) from the basolateral membrane to the apical cell surface." | 1.28 | Microtubule perturbation retards both the direct and the indirect apical pathway but does not affect sorting of plasma membrane proteins in intestinal epithelial cells (Caco-2). ( Bucher, K; Hauri, HP; Matter, K, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 10 (33.33) | 18.2507 |
2000's | 14 (46.67) | 29.6817 |
2010's | 5 (16.67) | 24.3611 |
2020's | 1 (3.33) | 2.80 |
Authors | Studies |
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Medellin, DC | 1 |
Zhou, Q | 1 |
Scott, R | 1 |
Hill, RM | 1 |
Frail, SK | 1 |
Dasari, R | 1 |
Ontiveros, SJ | 1 |
Pelly, SC | 1 |
van Otterlo, WA | 1 |
Betancourt, T | 1 |
Shuster, CB | 1 |
Hamel, E | 1 |
Bai, R | 1 |
LaBarbera, DV | 1 |
Rogelj, S | 1 |
Frolova, LV | 1 |
Kornienko, A | 1 |
Park, KS | 1 |
Schecterson, L | 1 |
Gumbiner, BM | 1 |
Ito, S | 1 |
Okuda, S | 1 |
Abe, M | 1 |
Fujimoto, M | 1 |
Onuki, T | 1 |
Nishimura, T | 1 |
Takeichi, M | 1 |
Bernard, D | 1 |
Mondesert, O | 1 |
Gomes, A | 1 |
Duthen, Y | 1 |
Lobjois, V | 1 |
Cussat-Blanc, S | 1 |
Ducommun, B | 1 |
Stolz, A | 1 |
Vogel, C | 1 |
Schneider, V | 1 |
Ertych, N | 1 |
Kienitz, A | 1 |
Yu, H | 1 |
Bastians, H | 1 |
Payne, CM | 1 |
Crowley-Skillicorn, C | 1 |
Bernstein, C | 1 |
Holubec, H | 1 |
Moyer, MP | 1 |
Bernstein, H | 1 |
Boilève, A | 1 |
Senovilla, L | 1 |
Vitale, I | 1 |
Lissa, D | 1 |
Martins, I | 1 |
Métivier, D | 1 |
van den Brink, S | 1 |
Clevers, H | 1 |
Galluzzi, L | 1 |
Castedo, M | 1 |
Kroemer, G | 1 |
Wang, YJ | 1 |
Jeng, JH | 1 |
Chen, RJ | 1 |
Tseng, H | 1 |
Chen, LC | 1 |
Liang, YC | 1 |
Lin, CH | 1 |
Chen, CH | 1 |
Chu, JS | 1 |
Ho, WL | 1 |
Ho, YS | 1 |
Zhang, H | 1 |
Shi, X | 1 |
Zhang, QJ | 1 |
Hampong, M | 1 |
Paddon, H | 1 |
Wahyuningsih, D | 1 |
Pelech, S | 2 |
Wang, Q | 1 |
Moyret-Lalle, C | 1 |
Couzon, F | 1 |
Surbiguet-Clippe, C | 1 |
Saurin, JC | 1 |
Lorca, T | 1 |
Navarro, C | 1 |
Puisieux, A | 1 |
Shin, HJ | 1 |
Baek, KH | 2 |
Jeon, AH | 1 |
Park, MT | 1 |
Lee, SJ | 1 |
Kang, CM | 1 |
Lee, HS | 1 |
Yoo, SH | 1 |
Chung, DH | 1 |
Sung, YC | 1 |
McKeon, F | 2 |
Lee, CW | 2 |
Quignon, F | 1 |
Rozier, L | 1 |
Lachages, AM | 1 |
Bieth, A | 1 |
Simili, M | 1 |
Debatisse, M | 1 |
Ha, GH | 1 |
Kim, HS | 1 |
Jeong, SJ | 1 |
Kim, CM | 1 |
Wang, JA | 1 |
Meyer, TF | 1 |
Rudel, T | 1 |
McCool, DJ | 1 |
Forstner, JF | 1 |
Forstner, GG | 1 |
Park, J | 1 |
Cartwright, CA | 1 |
Long, BH | 1 |
Fairchild, CR | 1 |
Yasui, W | 1 |
Ayhan, A | 1 |
Kitadai, Y | 1 |
Nishimura, K | 1 |
Yokozaki, H | 1 |
Ito, H | 1 |
Tahara, E | 1 |
Chazaud, B | 1 |
Muriel, MP | 1 |
Aubery, M | 1 |
Decastel, M | 1 |
Maksymowych, AB | 1 |
Simpson, LL | 1 |
Gupta, M | 1 |
Fan, S | 1 |
Zhan, Q | 1 |
Kohn, KW | 1 |
O'Connor, PM | 2 |
Pommier, Y | 1 |
Haier, J | 1 |
Nasralla, M | 1 |
Nicolson, GL | 1 |
Chen, XM | 1 |
LaRusso, NF | 1 |
Han, EK | 1 |
Tahir, SK | 1 |
Cherian, SP | 1 |
Collins, N | 1 |
Ng, SC | 1 |
Russo, P | 1 |
Ottoboni, C | 1 |
Crippa, A | 1 |
Riou, JF | 1 |
Tighe, A | 1 |
Johnson, VL | 1 |
Albertella, M | 1 |
Taylor, SS | 1 |
Andreassen, PR | 1 |
Lacroix, FB | 1 |
Lohez, OD | 1 |
Margolis, RL | 1 |
Sayed, M | 1 |
Wong, C | 1 |
Marotta, A | 1 |
Salh, B | 1 |
Viallard, V | 1 |
Castan, I | 1 |
Trocheris, V | 1 |
Lacombe, C | 1 |
Matter, K | 1 |
Bucher, K | 1 |
Hauri, HP | 1 |
30 other studies available for nocodazole and Colonic Neoplasms
Article | Year |
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Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Colonic Neoplasms; | 2016 |
Enhanced endothelial barrier function by monoclonal antibody activation of vascular endothelial cadherin.
Topics: Adherens Junctions; Antibodies, Monoclonal; Antigens, CD; Cadherins; Capillary Permeability; Cell Ad | 2021 |
Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells.
Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Actomyosin; Adherens Junctions; Biomechani | 2017 |
A checkpoint-oriented cell cycle simulation model.
Topics: Cell Proliferation; Colonic Neoplasms; Computer Simulation; Eukaryotic Cells; G1 Phase Cell Cycle Ch | 2019 |
Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
Topics: Apoptosis; Aurora Kinase B; Aurora Kinases; Carbazoles; Chromosome Aberrations; Colonic Neoplasms; D | 2009 |
Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis.
Topics: Cell Line, Tumor; Colonic Neoplasms; Deoxycholic Acid; Genomic Instability; Humans; Hydrophobic and | 2010 |
Immunosurveillance against tetraploidization-induced colon tumorigenesis.
Topics: Animals; Antineoplastic Agents; Calreticulin; Cell Transformation, Neoplastic; Colon; Colonic Neopla | 2013 |
Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice.
Topics: Adenocarcinoma; Animals; Antifungal Agents; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Pro | 2002 |
Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Arsenates; Blotting, Western; C | 2002 |
Alterations of anaphase-promoting complex genes in human colon cancer cells.
Topics: Anaphase-Promoting Complex-Cyclosome; Antineoplastic Agents; Apc3 Subunit, Anaphase-Promoting Comple | 2003 |
Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Cycle Proteins; Chromosoma | 2003 |
Sustained mitotic block elicits DNA breaks: one-step alteration of ploidy and chromosome integrity in mammalian cells.
Topics: Adenocarcinoma; Anaphase; Animals; Antineoplastic Agents; Cells, Cultured; Chromosomes; Colonic Neop | 2007 |
p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation.
Topics: Antineoplastic Agents; Cell Cycle; Chromosomal Instability; Colonic Neoplasms; Fluorescent Antibody | 2007 |
Cytoskeleton and motor proteins are required for the transcytosis of Neisseria gonorrhoeae through polarized epithelial cells.
Topics: Actins; Bacterial Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cytoskeletal Proteins; Dynei | 2008 |
Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct.
Topics: Adenocarcinoma; Biomarkers, Tumor; Calcimycin; Carbachol; Cell Size; Colchicine; Colonic Neoplasms; | 1995 |
Src activity increases and Yes activity decreases during mitosis of human colon carcinoma cells.
Topics: Aphidicolin; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; DNA Polymerase II; G2 Phase; Humans; Mi | 1995 |
Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase.
Topics: Anaphase; Cell Cycle; Colonic Neoplasms; Drug Screening Assays, Antitumor; G1 Phase; Humans; Nocodaz | 1994 |
Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas.
Topics: Blotting, Western; CDC2 Protein Kinase; Cell Cycle; Colonic Neoplasms; Gastric Mucosa; HeLa Cells; H | 1993 |
Organization of the endoplasmic reticulum-Golgi system is related to the state of enterocytic differentiation of human HT-29 cells.
Topics: Antineoplastic Agents; Brefeldin A; Cell Differentiation; Cell Division; Cell Membrane; Colonic Neop | 1996 |
Binding and transcytosis of botulinum neurotoxin by polarized human colon carcinoma cells.
Topics: Animals; Anti-Bacterial Agents; Biological Transport; Botulinum Toxins; Botulinum Toxins, Type A; Br | 1998 |
Inactivation of p53 increases the cytotoxicity of camptothecin in human colon HCT116 and breast MCF-7 cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Colonic Neoplasms | 1997 |
Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: role of integrin expression and cytoskeletal components.
Topics: Acrylamide; Antibodies; Cell Adhesion; Colchicine; Colonic Neoplasms; Cycloheximide; Cytochalasin D; | 1999 |
Mechanisms of attachment and internalization of Cryptosporidium parvum to biliary and intestinal epithelial cells.
Topics: Animals; Antigens, Tumor-Associated, Carbohydrate; Bile Ducts; Cattle; Cell Adhesion; Cell Line; Col | 2000 |
Modulation of paclitaxel resistance by annexin IV in human cancer cell lines.
Topics: Annexin A4; Blotting, Western; Colchicine; Colonic Neoplasms; DNA, Complementary; Drug Resistance, M | 2000 |
RPR-115135, a new non peptidomimetic farnesyltransferase inhibitor, induces G0/G1 arrest only in serum starved cells.
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell S | 2001 |
Aneuploid colon cancer cells have a robust spindle checkpoint.
Topics: Adenomatous Polyposis Coli Protein; Aneuploidy; Animals; Antineoplastic Agents; Cell Cycle; Chromoso | 2001 |
Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells.
Topics: 14-3-3 Proteins; Antineoplastic Agents; Biomarkers, Tumor; Colonic Neoplasms; Cyclin-Dependent Kinas | 2001 |
Protein kinase CK2 is involved in G2 arrest and apoptosis following spindle damage in epithelial cells.
Topics: Apoptosis; Casein Kinase II; Cell Line; Colonic Neoplasms; Cyclin B; Enzyme Activation; Enzyme Inhib | 2001 |
Fate of exogenous and newly synthesized cholesterol in intestinal cell lines.
Topics: Adenocarcinoma; Carcinoma; Cell Differentiation; Cholesterol; Cholesterol Esters; Colonic Neoplasms; | 1992 |
Microtubule perturbation retards both the direct and the indirect apical pathway but does not affect sorting of plasma membrane proteins in intestinal epithelial cells (Caco-2).
Topics: Adenocarcinoma; Cell Line; Cell Membrane; Colonic Neoplasms; Endocytosis; Epithelium; Humans; Kineti | 1990 |