nocodazole has been researched along with Cell Transformation, Neoplastic in 19 studies
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study we show that, in human breast cancer cells, chemical inhibition of Bone morphogenetic proteins (BMPs), but not Transforming Growth Factor-β (TGF-β), abrogates the mitotic arrest induced by nocodazole." | 3.78 | Bone morphogenetic protein (BMP) signaling regulates mitotic checkpoint protein levels in human breast cancer cells. ( Kang, J; Liu, N; Song, C; Yan, H; Zhu, S, 2012) |
| " Here, we report that EBNA2 can compromise mitotic spindle checkpoint (MSC) induced by the spindle inhibitor nocodazole and cause chromosomal instability (CIN) in HEp-2, U2-OS and BJAB cells." | 3.75 | Epstein-Barr virus nuclear antigen 2 disrupts mitotic checkpoint and causes chromosomal instability. ( Chen, JY; Chou, SF; Hsu, WB; Lai, CC; Lee, FY; Lin, CS; Pan, SH; Tai, CC; Tien, HF; Wang, WB, 2009) |
| "Unexpectedly, tetraploidization is also under the control of a cell-extrinsic mechanism determined by the immune system." | 1.39 | Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy. ( Castedo, M; Galluzzi, L; Kroemer, G; Senovilla, L, 2013) |
| "Colon organoids generated from tetraploid Tp53 (-/-) cells exhibit a close-to-normal morphology as compared to their diploid Tp53 (-/-) counterparts, yet the colonocytes constituting these organoids are characterized by an increased cell size and an elevated expression of the immunostimulatory protein calreticulin on the cell surface." | 1.39 | Immunosurveillance against tetraploidization-induced colon tumorigenesis. ( Boilève, A; Castedo, M; Clevers, H; Galluzzi, L; Kroemer, G; Lissa, D; Martins, I; Métivier, D; Senovilla, L; van den Brink, S; Vitale, I, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 11 (57.89) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Senovilla, L | 2 |
| Galluzzi, L | 2 |
| Castedo, M | 2 |
| Kroemer, G | 2 |
| Yang, S | 1 |
| Zhang, L | 1 |
| Liu, M | 1 |
| Chong, R | 1 |
| Ding, SJ | 1 |
| Chen, Y | 1 |
| Dong, J | 1 |
| Li, Z | 1 |
| Li, J | 1 |
| Bi, P | 1 |
| Lu, Y | 1 |
| Burcham, G | 1 |
| Elzey, BD | 1 |
| Ratliff, T | 1 |
| Konieczny, SF | 1 |
| Ahmad, N | 1 |
| Kuang, S | 1 |
| Liu, X | 1 |
| Schliekelman, M | 1 |
| Cowley, DO | 1 |
| O'Quinn, R | 1 |
| Oliver, TG | 1 |
| Lu, L | 1 |
| Salmon, ED | 1 |
| Van Dyke, T | 1 |
| Pan, SH | 1 |
| Tai, CC | 1 |
| Lin, CS | 1 |
| Hsu, WB | 1 |
| Chou, SF | 1 |
| Lai, CC | 1 |
| Chen, JY | 1 |
| Tien, HF | 1 |
| Lee, FY | 1 |
| Wang, WB | 1 |
| Medendorp, K | 1 |
| van Groningen, JJ | 1 |
| Vreede, L | 1 |
| Hetterschijt, L | 1 |
| Brugmans, L | 1 |
| van den Hurk, WH | 1 |
| van Kessel, AG | 1 |
| Yan, H | 1 |
| Zhu, S | 1 |
| Song, C | 1 |
| Liu, N | 1 |
| Kang, J | 1 |
| Boilève, A | 1 |
| Vitale, I | 1 |
| Lissa, D | 1 |
| Martins, I | 1 |
| Métivier, D | 1 |
| van den Brink, S | 1 |
| Clevers, H | 1 |
| Jiang, Y | 1 |
| Zhang, Y | 1 |
| Lees, E | 1 |
| Seghezzi, W | 1 |
| Kanda, A | 1 |
| Kawai, H | 1 |
| Suto, S | 1 |
| Kitajima, S | 1 |
| Sato, S | 1 |
| Takata, T | 1 |
| Tatsuka, M | 1 |
| Seeber, S | 1 |
| Issinger, OG | 1 |
| Holm, T | 1 |
| Kristensen, LP | 1 |
| Guerra, B | 1 |
| Zhang, H | 1 |
| Jin, Y | 1 |
| Chen, X | 1 |
| Jin, C | 1 |
| Law, S | 1 |
| Tsao, SW | 1 |
| Kwong, YL | 1 |
| Vecchione, A | 1 |
| Baldassarre, G | 1 |
| Ishii, H | 1 |
| Nicoloso, MS | 1 |
| Belletti, B | 1 |
| Petrocca, F | 1 |
| Zanesi, N | 1 |
| Fong, LY | 1 |
| Battista, S | 1 |
| Guarnieri, D | 1 |
| Baffa, R | 1 |
| Alder, H | 1 |
| Farber, JL | 1 |
| Donovan, PJ | 1 |
| Croce, CM | 1 |
| Nelyudova, A | 1 |
| Aksenov, N | 1 |
| Pospelov, V | 1 |
| Pospelova, T | 1 |
| Gerfaux, J | 1 |
| Macé, B | 1 |
| Chany-Fournier, F | 1 |
| Pompidou, A | 1 |
| Gloushankova, NA | 1 |
| Krendel, MF | 1 |
| Sirotkin, VA | 1 |
| Bonder, EM | 1 |
| Feder, HH | 1 |
| Vasiliev, JM | 1 |
| Gelfand, IM | 1 |
| Nishimura, Y | 1 |
| Sameni, M | 1 |
| Sloane, BF | 1 |
| Lagana, A | 1 |
| Vadnais, J | 1 |
| Le, PU | 1 |
| Nguyen, TN | 1 |
| Laprade, R | 1 |
| Nabi, IR | 1 |
| Noël, J | 1 |
| Khan, QA | 1 |
| Anderson, LM | 1 |
19 other studies available for nocodazole and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy.
Topics: Animals; Calreticulin; Cell Cycle; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA; End | 2013 |
CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation.
Topics: Antineoplastic Agents; Binding Sites; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Movement; Cell | 2013 |
Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.
Topics: Animals; Antineoplastic Agents; Benzamides; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformati | 2014 |
Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis.
Topics: Alleles; Aneuploidy; Animals; Cell Cycle Proteins; Cell Transformation, Neoplastic; Chromosome Segre | 2009 |
Epstein-Barr virus nuclear antigen 2 disrupts mitotic checkpoint and causes chromosomal instability.
Topics: Animals; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Transformation, Neopl | 2009 |
The renal cell carcinoma-associated oncogenic fusion protein PRCCTFE3 provokes p21 WAF1/CIP1-mediated cell cycle delay.
Topics: Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carcinoma, Renal Cell; Cell Cycle; Cell | 2009 |
Bone morphogenetic protein (BMP) signaling regulates mitotic checkpoint protein levels in human breast cancer cells.
Topics: Activins; Benzamides; Bone Morphogenetic Proteins; Breast Neoplasms; Calcium-Binding Proteins; Cell | 2012 |
Immunosurveillance against tetraploidization-induced colon tumorigenesis.
Topics: Animals; Antineoplastic Agents; Calreticulin; Cell Transformation, Neoplastic; Colon; Colonic Neopla | 2013 |
AuroraA overexpression overrides the mitotic spindle checkpoint triggered by nocodazole, a microtubule destabilizer.
Topics: Aurora Kinases; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; H | 2003 |
Aurora-B/AIM-1 kinase activity is involved in Ras-mediated cell transformation.
Topics: Aneuploidy; Animals; Antineoplastic Agents; Aurora Kinase B; Aurora Kinases; BALB 3T3 Cells; Cell Tr | 2005 |
Validation of protein kinase CK2 as oncological target.
Topics: Apoptosis; Casein Kinase II; Catalytic Domain; Cell Transformation, Neoplastic; Flow Cytometry; HCT1 | 2005 |
Papillomavirus type 16 E6/E7 and human telomerase reverse transcriptase in esophageal cell immortalization and early transformation.
Topics: Aurora Kinases; Blotting, Western; Cadherins; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cu | 2007 |
Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.
Topics: Animals; Antineoplastic Agents; Carcinogens; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Pro | 2007 |
By blocking apoptosis, Bcl-2 in p38-dependent manner promotes cell cycle arrest and accelerated senescence after DNA damage and serum withdrawal.
Topics: Adenovirus E1A Proteins; Animals; Apoptosis; Cell Cycle; Cell Transformation, Neoplastic; Cellular S | 2007 |
Early nuclear structural changes of transformed human amniotic cells (WISH) in presence of type IV collagen detected by the nuclear refringency assay.
Topics: Amnion; Autoanalysis; Benzimidazoles; Birefringence; Cell Adhesion; Cell Line; Cell Nucleus; Cell Su | 1984 |
Dynamics of active lamellae in cultured epithelial cells: effects of expression of exogenous N-ras oncogene.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Concanavalin A; Cytoskeleton; | 1995 |
Malignant transformation alters intracellular trafficking of lysosomal cathepsin D in human breast epithelial cells.
Topics: Animals; Antigens, CD; Biological Transport; Breast; Cathepsin D; Cell Line, Transformed; Cell Trans | 1998 |
Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1.
Topics: Actin Cytoskeleton; Actins; Amiloride; Animals; Cell Adhesion; Cell Line; Cell Line, Transformed; Ce | 2000 |
Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveo | 2001 |