nocodazole has been researched along with Carcinoma, Hepatocellular in 13 studies
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
Excerpt | Relevance | Reference |
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"Pretreatment of human hepatoma cells with a caspase 3 inhibitor z-DEVD-FMK, prior to the treatment with an antimicrotubule drug nocodazole, abrogates the mitotic arrest, suggesting that caspase 3 (or a caspase 3-like enzyme) might be involved in mitotic-spindle checkpoint." | 1.33 | Caspase 3, periodically expressed and activated at G2/M transition, is required for nocodazole-induced mitotic checkpoint. ( Hsu, SL; Huang, CY; Tang, MJ; Tien, AC; Wu, YM; Yin, SC; Yu, CT, 2006) |
"This phenomenon is specific for hepatoma cell lines or primarily cultured hepatocytes." | 1.32 | pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes. ( Arai, H; Arita, M; Horiguchi, M; Inoue, K; Kaempf-Rotzoll, DE; Tsujimoto, M, 2003) |
"In polarized HepG2 hepatoma cells, sphingolipids are transported to the apical, bile canalicular membrane by two different transport routes, as revealed with fluorescently tagged sphingolipid analogs." | 1.30 | Actin filaments and microtubules are involved in different membrane traffic pathways that transport sphingolipids to the apical surface of polarized HepG2 cells. ( Hoekstra, D; Klappe, K; van IJzendoorn, SC; Zaal, KJ; Zegers, MM, 1998) |
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 1 (7.69) | 18.7374 |
1990's | 2 (15.38) | 18.2507 |
2000's | 8 (61.54) | 29.6817 |
2010's | 1 (7.69) | 24.3611 |
2020's | 1 (7.69) | 2.80 |
Authors | Studies |
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Deng, Z | 1 |
Chen, G | 1 |
Liu, S | 1 |
Li, Y | 1 |
Zhong, J | 1 |
Zhang, B | 1 |
Li, L | 1 |
Huang, H | 1 |
Wang, Z | 1 |
Xu, Q | 1 |
Deng, X | 1 |
Maldonado, EN | 1 |
Patnaik, J | 1 |
Mullins, MR | 1 |
Lemasters, JJ | 1 |
Wang, Q | 1 |
Moyret-Lalle, C | 1 |
Couzon, F | 1 |
Surbiguet-Clippe, C | 1 |
Saurin, JC | 1 |
Lorca, T | 1 |
Navarro, C | 1 |
Puisieux, A | 1 |
Horiguchi, M | 1 |
Arita, M | 1 |
Kaempf-Rotzoll, DE | 1 |
Tsujimoto, M | 1 |
Inoue, K | 1 |
Arai, H | 1 |
Hsu, JM | 1 |
Lee, YC | 1 |
Yu, CT | 2 |
Huang, CY | 2 |
Gonçalves, C | 1 |
Mennesson, E | 1 |
Fuchs, R | 1 |
Gorvel, JP | 1 |
Midoux, P | 1 |
Pichon, C | 1 |
Hsu, SL | 1 |
Yin, SC | 1 |
Tang, MJ | 1 |
Tien, AC | 1 |
Wu, YM | 1 |
Dvorák, Z | 1 |
Vrzal, R | 1 |
Ulrichová, J | 1 |
Pascussi, JM | 1 |
Maurel, P | 1 |
Modriansky, M | 1 |
Zegers, MM | 1 |
Zaal, KJ | 1 |
van IJzendoorn, SC | 1 |
Klappe, K | 1 |
Hoekstra, D | 1 |
Duvet, S | 1 |
Cocquerel, L | 1 |
Pillez, A | 1 |
Cacan, R | 1 |
Verbert, A | 1 |
Moradpour, D | 1 |
Wychowski, C | 1 |
Dubuisson, J | 1 |
Harada, M | 1 |
Sakisaka, S | 1 |
Terada, K | 1 |
Kimura, R | 1 |
Kawaguchi, T | 1 |
Koga, H | 1 |
Taniguchi, E | 1 |
Sasatomi, K | 1 |
Miura, N | 1 |
Suganuma, T | 1 |
Fujita, H | 1 |
Furuta, K | 1 |
Tanikawa, K | 1 |
Sugiyama, T | 1 |
Sata, M | 1 |
Rosin-Arbesfeld, R | 1 |
Ihrke, G | 1 |
Bienz, M | 1 |
Miller-Faurès, A | 1 |
Blave, A | 1 |
Caudron, M | 1 |
Sene, C | 1 |
Miller, AO | 1 |
13 other studies available for nocodazole and Carcinoma, Hepatocellular
Article | Year |
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Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Prol | 2020 |
Free tubulin modulates mitochondrial membrane potential in cancer cells.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Membrane; Colchic | 2010 |
Alterations of anaphase-promoting complex genes in human colon cancer cells.
Topics: Anaphase-Promoting Complex-Cyclosome; Antineoplastic Agents; Apc3 Subunit, Anaphase-Promoting Comple | 2003 |
pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.
Topics: Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Brefeldin A; Carcinoma, Hepatoce | 2003 |
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Blotting, Western; Carcinoma, Hepatocellular; | 2004 |
Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells.
Topics: Biological Transport; Carcinoma, Hepatocellular; Cell Line, Tumor; Chlorpromazine; Clathrin; Endosom | 2004 |
Caspase 3, periodically expressed and activated at G2/M transition, is required for nocodazole-induced mitotic checkpoint.
Topics: Carcinoma, Hepatocellular; Caspase 3; Caspase Inhibitors; Caspases; Cell Culture Techniques; Cell Li | 2006 |
Involvement of cytoskeleton in AhR-dependent CYP1A1 expression.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Cell Survival; Cells, Cultured; | 2006 |
Actin filaments and microtubules are involved in different membrane traffic pathways that transport sphingolipids to the apical surface of polarized HepG2 cells.
Topics: Actin Cytoskeleton; Actins; Bile Canaliculi; Biological Transport; Carcinoma, Hepatocellular; Cell M | 1998 |
Hepatitis C virus glycoprotein complex localization in the endoplasmic reticulum involves a determinant for retention and not retrieval.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dimerization; Endoplasmic Reticulum; Golgi Apparatus; | 1998 |
Role of ATP7B in biliary copper excretion in a human hepatoma cell line and normal rat hepatocytes.
Topics: Adaptor Protein Complex gamma Subunits; Adenosine Triphosphatases; Animals; Antigens, CD; Bile Canal | 2000 |
Actin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cells.
Topics: Actins; Adenomatous Polyposis Coli Protein; Animals; Antineoplastic Agents; Bridged Bicyclo Compound | 2001 |
Flow cytometric analysis of hepatoma tissue and HeLa cells grown on various types of microbeads using hydroxyurea, nocodazole and aphidicolin in succession.
Topics: Aphidicolin; Benzimidazoles; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cytological Techn | 1985 |