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nocodazole and Abnormalities, Autosome

nocodazole has been researched along with Abnormalities, Autosome in 20 studies

Research Excerpts

ExcerptRelevanceReference
"Unexpectedly, tetraploidization is also under the control of a cell-extrinsic mechanism determined by the immune system."1.39Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy. ( Castedo, M; Galluzzi, L; Kroemer, G; Senovilla, L, 2013)
"Osteosarcomas are the most prevalent primary bone tumors found in pediatric patients."1.35Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). ( Aung, KZ; Cool, SM; Galindo, M; Gupta, A; Leong, DT; Ling, L; Nathan, SS; Pereira, BP; Pho, RW; Salto-Tellez, M; Stein, GS; van Wijnen, AJ; Zhou, Y, 2009)
"Nocodazole treated, cyclin B1-depleted HeLa cells arrested but exited that arrest at higher rates than controls, suggesting that the duration of the spindle checkpoint was affected."1.35Cyclin B1 is rate limiting but not essential for mitotic entry and progression in mammalian somatic cells. ( Jacobberger, JW; Lam, M; Soni, DV; Sramkoski, RM; Stefan, T, 2008)
"Aneuploidy is a key process in tumorigenesis."1.33FAT10 plays a role in the regulation of chromosomal stability. ( Chong, SS; Jeang, KT; Kan, A; Kon, OL; Lee, CG; Leong, SH; Ooi, LL; Ren, J, 2006)
"Our results suggest that elimination of aneuploid cells does occur."1.31Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules. ( Cundari, E; Decordier, I; Dillen, L; Kirsch-Volders, M, 2002)
"This pattern of chromosomal aberrations is consistent with a mechanism involving the impairment of chromosome segregation fidelity during mitotic cell division."1.31Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations. ( Auer, G; Difilippantonio, MJ; Ghadimi, BM; Jauho, A; Neumann, T; Ried, T; Sackett, DL; Schröck, E, 2000)
"Despite the fact that aneuploidy is a major genetic cause of human morbidity and mortality, antimutagenicity studies have used predominantly short-term tests that detect gene mutations, chromosomal aberrations, and micronuclei."1.29Utility of a test for chromosomal malsegregation in Saccharomyces cerevisiae strain D61.M for the detection of antianeugens: test of the model combination of chlorophyllin and nocodazole. ( Brockman, HE; Mayer, VW; Verma, A, 1996)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's3 (15.00)18.2507
2000's12 (60.00)29.6817
2010's4 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Varadkar, P1
Abbasi, F1
Takeda, K1
Dyson, JJ1
McCright, B1
Bellido, A1
Hermosa, B1
Ciudad, T1
Larriba, G1
Senovilla, L1
Galluzzi, L1
Castedo, M1
Kroemer, G1
Jacobs, K1
Van de Velde, H1
De Paepe, C1
Sermon, K1
Spits, C1
Stolz, A1
Vogel, C1
Schneider, V1
Ertych, N1
Kienitz, A1
Yu, H2
Bastians, H1
Pereira, BP1
Zhou, Y1
Gupta, A2
Leong, DT1
Aung, KZ1
Ling, L1
Pho, RW1
Galindo, M1
Salto-Tellez, M1
Stein, GS1
Cool, SM1
van Wijnen, AJ1
Nathan, SS1
Decordier, I1
Dillen, L1
Cundari, E1
Kirsch-Volders, M1
Shin, HJ1
Baek, KH1
Jeon, AH1
Kim, SJ1
Jang, KL1
Sung, YC1
Kim, CM1
Lee, CW1
Inaba, S1
Wong, OK1
Fang, G1
Liu, J1
Yih, LH1
Lee, TC1
Brown, EJ1
Wang, RH1
Deng, CX1
Ren, J1
Kan, A1
Leong, SH1
Ooi, LL1
Jeang, KT1
Chong, SS1
Kon, OL1
Lee, CG1
Soni, DV1
Sramkoski, RM1
Lam, M1
Stefan, T1
Jacobberger, JW1
Verma, A1
Brockman, HE1
Mayer, VW2
Burns, EM1
Christopoulou, L1
Corish, P1
Tyler-Smith, C1
Kitagawa, R1
Rose, AM1
Ghadimi, BM1
Sackett, DL1
Difilippantonio, MJ1
Schröck, E1
Neumann, T1
Jauho, A1
Auer, G1
Ried, T1
Michel, LS1
Liberal, V1
Chatterjee, A1
Kirchwegger, R1
Pasche, B1
Gerald, W1
Dobles, M1
Sorger, PK1
Murty, VV1
Benezra, R1
Goin, CJ1

Other Studies

20 other studies available for nocodazole and Abnormalities, Autosome

ArticleYear
PP2A-B56γ is required for an efficient spindle assembly checkpoint.
    Cell cycle (Georgetown, Tex.), 2017, Jun-18, Volume: 16, Issue:12

    Topics: Animals; Apoptosis; Cell Cycle Proteins; Cells, Cultured; Chromosome Aberrations; Cyclin B1; M Phase

2017
Role of homologous recombination genes RAD51, RAD52, and RAD59 in the repair of lesions caused by γ-radiation to cycling and G2/M-arrested cells of Candida albicans.
    Cellular microbiology, 2018, Volume: 20, Issue:12

    Topics: Candida albicans; Cell Cycle Checkpoints; Chromosome Aberrations; DNA Breaks, Double-Stranded; DNA R

2018
Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy.
    Annals of the New York Academy of Sciences, 2013, Volume: 1284

    Topics: Animals; Calreticulin; Cell Cycle; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA; End

2013
Mitotic spindle disruption in human preimplantation embryos activates the spindle assembly checkpoint but not apoptosis until Day 5 of development.
    Molecular human reproduction, 2017, 05-01, Volume: 23, Issue:5

    Topics: Apoptosis; Blastocyst; Chromosome Aberrations; Embryo Culture Techniques; Embryo, Mammalian; Embryon

2017
Pharmacologic abrogation of the mitotic spindle checkpoint by an indolocarbazole discovered by cellular screening efficiently kills cancer cells.
    Cancer research, 2009, May-01, Volume: 69, Issue:9

    Topics: Apoptosis; Aurora Kinase B; Aurora Kinases; Carbazoles; Chromosome Aberrations; Colonic Neoplasms; D

2009
Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).
    Journal of cellular physiology, 2009, Volume: 221, Issue:3

    Topics: Adolescent; Animals; Antigens, CD; Asian People; Calcification, Physiologic; Cell Cycle; Cell Dediff

2009
Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules.
    Mutagenesis, 2002, Volume: 17, Issue:4

    Topics: Adult; Aneuploidy; Apoptosis; Benzimidazoles; Carbamates; Cell Nucleus; Cells, Cultured; Chromosome

2002
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation.
    Oncogene, 2003, Jun-19, Volume: 22, Issue:25

    Topics: Acetylation; Acetyltransferases; Apoptosis; Biomarkers; Cell Cycle Proteins; Chromosome Aberrations;

2003
Breast cancer-specific gene 1 interacts with the mitotic checkpoint kinase BubR1.
    Oncogene, 2003, Oct-23, Volume: 22, Issue:48

    Topics: Cell Cycle Proteins; Cell Line, Tumor; Chromosome Aberrations; gamma-Synuclein; Humans; Mitosis; Neo

2003
Induction of C-anaphase and diplochromosome through dysregulation of spindle assembly checkpoint by sodium arsenite in human fibroblasts.
    Cancer research, 2003, Oct-15, Volume: 63, Issue:20

    Topics: Anaphase; Anaphase-Promoting Complex-Cyclosome; Arsenites; Calcium-Binding Proteins; Cdc20 Proteins;

2003
Analysis of cell cycle progression and genomic integrity in early lethal knockouts.
    Methods in molecular biology (Clifton, N.J.), 2004, Volume: 280

    Topics: Animals; Apoptosis; Blastocyst; Blotting, Southern; Cell Cycle; Cell Cycle Proteins; Cell Division;

2004
A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Dec-07, Volume: 101, Issue:49

    Topics: Animals; Apoptosis; BRCA1 Protein; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Line; Cell Nu

2004
FAT10 plays a role in the regulation of chromosomal stability.
    The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16

    Topics: Aneuploidy; Apoptosis; Blotting, Western; Calcium-Binding Proteins; Cell Cycle; Cell Cycle Proteins;

2006
Cyclin B1 is rate limiting but not essential for mitotic entry and progression in mammalian somatic cells.
    Cell cycle (Georgetown, Tex.), 2008, May-01, Volume: 7, Issue:9

    Topics: Anaphase; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Proliferation; Chromosome Aberrations; Chro

2008
Utility of a test for chromosomal malsegregation in Saccharomyces cerevisiae strain D61.M for the detection of antianeugens: test of the model combination of chlorophyllin and nocodazole.
    Mutation research, 1996, Oct-28, Volume: 358, Issue:1

    Topics: Aneuploidy; Antimutagenic Agents; Antineoplastic Agents; Cell Division; Chlorophyllides; Chromosome

1996
Quantitative measurement of mammalian chromosome mitotic loss rates using the green fluorescent protein.
    Journal of cell science, 1999, Volume: 112 ( Pt 16)

    Topics: Aneuploidy; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Buffers; Caffeine; Ce

1999
Components of the spindle-assembly checkpoint are essential in Caenorhabditis elegans.
    Nature cell biology, 1999, Volume: 1, Issue:8

    Topics: Animals; Benomyl; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium-Binding Proteins;

1999
Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations.
    Genes, chromosomes & cancer, 2000, Volume: 27, Issue:2

    Topics: Aneuploidy; Caco-2 Cells; Cell Division; Centrosome; Chromosome Aberrations; Colorectal Neoplasms; D

2000
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells.
    Nature, 2001, Jan-18, Volume: 409, Issue:6818

    Topics: Anaphase; Animals; Antineoplastic Agents; Calcium-Binding Proteins; Carrier Proteins; Cell Cycle Pro

2001
Observations on chromosome loss detection by multiple recessive marker expression in strain D61.M of Saccharomyces cerevisiae.
    Mutation research, 1989, Volume: 224, Issue:4

    Topics: Adenine; Chromosome Aberrations; Cycloheximide; Ethyl Methanesulfonate; Genes, Recessive; Genetic Ma

1989