noc-9 has been researched along with Leukemia* in 1 studies
1 other study(ies) available for noc-9 and Leukemia
Article | Year |
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Synthesis and in vitro anti-leukemic activity of structural analogues of JS-K, an anti-cancer lead compound.
Structural analogues of JS-K, an anti-cancer lead compound, were prepared and their in vitro anti-leukemic activity was determined. The rate of nitric oxide release from the corresponding diazeniumdiolate anions did not appear to affect the anti-leukemic activity of the prodrug forms. Two compounds with potent inhibitory activity and a potentially favorable toxicological profile were identified. Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Azo Compounds; Combinatorial Chemistry Techniques; Glutathione; Glutathione Transferase; HL-60 Cells; Humans; Leukemia; Models, Molecular; Molecular Structure; Nitric Oxide Donors; Piperazines; Prodrugs | 2008 |