nobiletin has been researched along with Disease Models, Animal in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (13.89) | 29.6817 |
| 2010's | 19 (52.78) | 24.3611 |
| 2020's | 12 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ertekin, A; Gokceoglu, A; Kabak, YB; Karaca, E; Sozmen, M; Yarim, GF; Yarim, M | 1 |
| Chai, W; Mei, Z; Nie, H; Xiang, Z; Xu, R; Zhang, H; Zhang, J; Zhang, P | 1 |
| Gao, FJ; Hu, FY; Wang, DD; Wu, JH; Xu, P; Zhang, XJ | 1 |
| Du, J; Lan, X; Li, Y; Liu, N; Ma, H; Ma, L; Peng, X; Tian, M; Yang, J; Yu, J; Zheng, P; Zhu, C | 1 |
| Fan, C; Li, J; Mei, F; Wang, S; Xi, R; Yang, J; Yin, Q; Yu, Y; Zhang, S; Zhang, X | 1 |
| Chen, M; Chen, X; Chen, Y; Li, Y; Shen, J; Sun, Q; Wu, J; Yuan, M; Zhang, R | 1 |
| El-Maraghy, SA; Essam, RM; Kortam, MA; Reda, A | 1 |
| Cellat, M; Gokcek, İ; Güvenç, M; İsler, CT; Özkan, H; Uyar, A; Yakan, A | 1 |
| Gao, W; Huang, Z; Jiang, C; Jiang, R; Lin, C; Lin, D | 1 |
| Lai, A; Lappas, M; Nguyen-Ngo, C; Quak, S; Salomon, C; Willcox, JC | 1 |
| Gao, Z; Liang, Z; Liu, Z; Wu, X; Zeng, L; Zheng, D | 1 |
| Chen, Z; Escobedo, G; Kim, E; Lim, JY; Morales, R; Nohara, K; Wirianto, M; Yoo, SH | 1 |
| Chen, L; Liu, Y; Qu, Y; Wang, D; Xiao, X; Zhu, Y | 1 |
| Bischoff, SC; Feilhauer, K; Gommeringer, S; Hagenlocher, Y; Held, A; Köninger, J; Lorentz, A | 1 |
| Arora, RC; Cunningham, C | 1 |
| Shao, X; Wei, X | 1 |
| Bartman, CM; Eckle, T; Gile, J; Oyama, Y; Sehrt, D | 1 |
| Nakajima, A; Ohizumi, Y | 1 |
| Aoyama, Y; Kim, HC; Mimaki, Y; Nagai, T; Nakai, T; Nakajima, A; Nguyen, TT; Ohizumi, Y; Shin, EJ; Yamada, K; Yamada, S; Yokosuka, A | 1 |
| Fukunaga, K; Mimaki, Y; Ohizumi, Y; Yabuki, Y; Yokosuka, A | 1 |
| Agato, Y; Asai, T; Asakawa, T; Fukuta, T; Ishii, T; Kan, T; Ohizumi, Y; Oku, N; Oyama, D; Sato, A; Shimizu, K; Yamada, S; Yasuda, N | 1 |
| Choi, IY; Choi, MS; Chu, JW; Jang, MC; Jeon, MT; Jeong, KH; Jung, UJ; Kim, HD; Kim, SR; Yang, SJ | 1 |
| Guan, S; Li, B; Liu, W; Tang, Q; Zhu, R | 1 |
| Aoyama, Y; Kim, HC; Mimaki, Y; Nagai, T; Nakajima, A; Nam, Y; Ohizumi, Y; Shin, EJ; Yamada, K; Yokoi, T; Yokosuka, A | 1 |
| Kawahata, I; Yamakuni, T | 1 |
| Choi, BK; Jung, JY; Jung, WH; Kim, TW; Lee, DR; Lim, JH; Suh, JW; Yang, SH | 1 |
| Bai, X; Chen, L; Chen, R; Cui, L; Wang, L; Zhang, C; Zhang, J; Zhang, L; Zhang, X; Zhao, T; Zhao, X; Zhao, Y; Zhu, C | 1 |
| Matsuzaki, K; Mimaki, Y; Nakajima, A; Ogino, K; Ohizumi, Y; Onozuka, H; Saigusa, D; Sashida, Y; Shin, RW; Tetsu, N; Yamakuni, T; Yokosuka, A | 1 |
| Nakajima, A; Ohizumi, Y; Yamakuni, T | 1 |
| Su, M; Wang, Y; Yin, J; Zhang, H | 1 |
| Cui, CC; Feng, J; Xu, HL; Yi, LT; Zhan, X; Zhou, LP | 1 |
| Chang, CD; Liao, MH; Lin, PY; Shih, WL; Wu, HY; Yu, FL | 1 |
| Hirata, M; Inada, M; Matsumoto, C; Miyaura, C; Tominari, T | 1 |
| Han, HS; Lee, J; Lim, SH; Song, KS; Yang, EJ | 1 |
| Li, SN; Tao, J; Wu, YQ; Zhou, CH | 1 |
| Haque, AM; Hashimoto, M; Matsuzaki, K; Mimaki, Y; Ohizumi, Y; Sashida, Y; Shido, O; Yamakuni, T | 1 |
2 review(s) available for nobiletin and Disease Models, Animal
| Article | Year |
|---|---|
Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer's Disease and Parkinson's Disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Biomarkers; Citrus; Disease Models, Animal; Drug Evaluation, Preclinical; Flavones; Flavonoids; Humans; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Signal Transduction | 2019 |
Pharmacological action of nobiletin, a component of AURANTII NOBILIS PERICARPIUM with anti-dementia activity, and its application for development of functional foods.
Topics: Alzheimer Disease; Animals; Cognition Disorders; Disease Models, Animal; Flavones; Foods, Specialized; Hippocampus; Humans; Learning Disabilities; Memory Disorders; Mice; Neurons; Plants, Medicinal; Rats; Signal Transduction | 2008 |
34 other study(ies) available for nobiletin and Disease Models, Animal
| Article | Year |
|---|---|
Nobiletin attenuates inflammation via modulating proinflammatory and antiinflammatory cytokine expressions in an autoimmune encephalomyelitis mouse model.
Topics: Animals; Antioxidants; Brain; Cytokines; Disease Models, Animal; DNA, Complementary; Encephalomyelitis, Autoimmune, Experimental; Flavones; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Real-Time Polymerase Chain Reaction; RNA; Spinal Cord | 2022 |
Potential of nobiletin against Alzheimer's disease through inhibiting neuroinflammation.
Topics: Alzheimer Disease; Animals; Cytokines; Disease Models, Animal; Flavones; HMGB Proteins; Humans; Lipopolysaccharides; Mice; Mice, Transgenic; Neuroinflammatory Diseases; Nigericin | 2022 |
Nobiletin protects retinal ganglion cells in models of ocular hypertension in vivo and hypoxia in vitro.
Topics: Animals; Disease Models, Animal; Glaucoma; Hypoxia; Neuroprotective Agents; NF-E2-Related Factor 2; Ocular Hypertension; Rats; Retinal Ganglion Cells | 2022 |
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Topics: Analgesics; Animals; Brain-Derived Neurotrophic Factor; Constriction; Disease Models, Animal; Flavones; Hyperalgesia; Interferon Regulatory Factors; Mice; Neuralgia; Sciatic Nerve | 2022 |
Nobiletin attenuates monocrotaline-induced pulmonary arterial hypertension through PI3K/Akt/STAT3 pathway.
Topics: Animals; Cytokines; Disease Models, Animal; Hypertension, Pulmonary; Monocrotaline; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats | 2023 |
Nobiletin inhibits de novo FA synthesis to alleviate gastric cancer progression by regulating endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; Lipids; Stomach Neoplasms | 2023 |
The citrus flavonoid "Nobiletin" impedes STZ-induced Alzheimer's disease in a mouse model through regulating autophagy mastered by SIRT1/FoxO3a mechanism.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Autophagy; Citrus; Disease Models, Animal; Flavonoids; Mice; Sirtuin 1 | 2023 |
Nobiletin Protects from Renal Ischemia-Reperfusion Injury in Rats by Suppressing Inflammatory Cytokines and Regulating iNOS-eNOS Expressions.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Flavones; Inflammation Mediators; Kidney; Kidney Diseases; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats, Wistar; Reperfusion Injury; Signal Transduction | 2020 |
Nobiletin enhances the survival of random pattern skin flaps: Involvement of enhancing angiogenesis and inhibiting oxidative stress.
Topics: Animals; Antioxidants; Disease Models, Animal; Flavones; Graft Survival; Humans; Laser-Doppler Flowmetry; Male; Malondialdehyde; Necrosis; Neovascularization, Physiologic; Oxidative Stress; Rats; Skin; Skin Transplantation; Superoxide Dismutase; Surgical Flaps | 2020 |
Nobiletin exerts anti-diabetic and anti-inflammatory effects in an in vitro human model and in vivo murine model of gestational diabetes.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Diabetes, Gestational; Disease Models, Animal; Female; Flavones; Glucose; Humans; Hypoglycemic Agents; Mice; Muscle, Skeletal; Placenta; Pregnancy; Subcutaneous Fat | 2020 |
Nobiletin ameliorates cardiac impairment and alleviates cardiac remodeling after acute myocardial infarction in rats via JNK regulation.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Flavones; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Myoblasts; Myocardial Infarction; Myocardium; Rats; Ventricular Remodeling | 2021 |
Effects of the Clock Modulator Nobiletin on Circadian Rhythms and Pathophysiology in Female Mice of an Alzheimer's Disease Model.
Topics: Alzheimer Disease; Animals; Circadian Rhythm; Disease Models, Animal; Female; Flavones; Gene Expression Regulation; Mice | 2021 |
Nobiletin prevents cadmium-induced neuronal apoptosis by inhibiting reactive oxygen species and modulating JNK/ERK1/2 and Akt/mTOR networks in rats.
Topics: Animals; Apoptosis; Cadmium; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavones; Glutathione; In Situ Nick-End Labeling; Male; Malondialdehyde; MAP Kinase Kinase 4; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oncogene Protein v-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2018 |
Nobiletin acts anti-inflammatory on murine IL-10
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cells, Cultured; Colitis; Disease Models, Animal; Fibroblasts; Flavones; Humans; Interleukin-10; Intestines; Male; Mice; Mice, Inbred BALB C | 2019 |
Losing Sleep Over Delirium.
Topics: Animals; Delirium; Disease Models, Animal; Flavones; Mice; Sleep | 2018 |
Nobiletin alleviates endometriosis via down-regulating NF-κB activity in endometriosis mouse model.
Topics: Animals; Anti-Inflammatory Agents; Cadherins; Choristoma; Disease Models, Animal; Ectopic Gene Expression; Endometriosis; Endometrium; Female; Flavones; Humans; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Mice; Mice, Inbred C57BL; NF-kappa B; Nociception; Proliferating Cell Nuclear Antigen; Signal Transduction; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2018 |
The Circadian PER2 Enhancer Nobiletin Reverses the Deleterious Effects of Midazolam in Myocardial Ischemia and Reperfusion Injury.
Topics: Animals; Disease Models, Animal; Flavones; Mice; Mice, Knockout; Midazolam; Myocardial Ischemia; Period Circadian Proteins; Reperfusion Injury | 2018 |
Nobiletin, a citrus flavonoid, ameliorates cognitive impairment, oxidative burden, and hyperphosphorylation of tau in senescence-accelerated mouse.
Topics: Aging; Analysis of Variance; Animals; Antioxidants; Body Weight; Case-Control Studies; Cognition Disorders; Conditioning, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; Flavones; Glutathione; Glutathione Peroxidase; Lipid Metabolism; Male; Maze Learning; Mice; Mice, Transgenic; Oxidative Stress; Phosphorylation; Protein Carbonylation; Superoxide Dismutase; tau Proteins | 2013 |
Nobiletin treatment improves motor and cognitive deficits seen in MPTP-induced Parkinson model mice.
Topics: Animals; Antioxidants; Avoidance Learning; Brain; Calcium Channel Blockers; Cognition Disorders; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Flavones; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Tissue Proteins; Parkinsonian Disorders; Psychomotor Performance; Signal Transduction | 2014 |
Neuroprotective effect of nobiletin on cerebral ischemia-reperfusion injury in transient middle cerebral artery-occluded rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain; Brain Edema; Disease Models, Animal; Flavones; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Motor Activity; Neurons; Neuroprotective Agents; Neutrophils; Rats; Rats, Wistar; Reperfusion Injury; Treatment Outcome | 2014 |
Nobiletin protects dopaminergic neurons in the 1-methyl-4-phenylpyridinium-treated rat model of Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Disease Models, Animal; Dopaminergic Neurons; Female; Flavones; Glial Cell Line-Derived Neurotrophic Factor; Humans; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2015 |
Nobiletin Inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration and attenuates neointimal hyperplasia in a rat carotid artery injury model.
Topics: Animals; Antioxidants; Aorta, Thoracic; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Flavones; Gene Expression Regulation; Male; Muscle, Smooth, Vascular; Neointima; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2014 |
Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD).
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Brain; Disease Models, Animal; Flavones; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Oxidative Stress; Peptide Fragments; Recognition, Psychology | 2015 |
[Pharmacological superiority of nobiletin-rich Citrus reticulata peel, a multicomponent drug, over nobiletin alone regarding anti-dementia action].
Topics: Animals; Citrus; Dementia; Disease Models, Animal; Dizocilpine Maleate; Flavones; Humans; Mice; Phytotherapy | 2015 |
A polymethoxy flavonoids-rich Citrus aurantium extract ameliorates ethanol-induced liver injury through modulation of AMPK and Nrf2-related signals in a binge drinking mouse model.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Binge Drinking; Citrus; Disease Models, Animal; Ethanol; Flavones; Flavonoids; Heme Oxygenase-1; Inflammation; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Plant Extracts; Silymarin; Tumor Necrosis Factor-alpha | 2015 |
Nobiletin promotes antioxidant and anti-inflammatory responses and elicits protection against ischemic stroke in vivo.
Topics: Animals; Antioxidants; Brain Edema; Brain Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Flavones; Functional Laterality; Gene Expression Regulation; Heme Oxygenase-1; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Nervous System Diseases; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Sprague-Dawley; Superoxide Dismutase-1 | 2016 |
Nobiletin, a citrus flavonoid, improves memory impairment and Abeta pathology in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Citrus; Disease Models, Animal; Flavones; Flavonoids; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2008 |
[Effect of nobiletin on K562 cells xenograft in nude mice].
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Citrus; Disease Models, Animal; Flavones; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms; Transplantation, Heterologous; Vascular Endothelial Growth Factors | 2009 |
Involvement of monoaminergic systems in the antidepressant-like effect of nobiletin.
Topics: Adrenergic Antagonists; Animals; Antidepressive Agents; Benzazepines; Cyproheptadine; Depression; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Flavones; Fluoxetine; Hindlimb Suspension; Male; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Prazosin; Propranolol; Pyridines; Serotonin Antagonists; Sulpiride; Swimming; Yohimbine | 2011 |
Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flavones; Fluorescent Antibody Technique; Glucose-6-Phosphate Isomerase; Humans; Immunoprecipitation; Liver Neoplasms; Luciferases; Lung Neoplasms; Male; Matrix Metalloproteinase 3; Mice; Mice, Nude; Neovascularization, Pathologic; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta; Triterpenes; Tumor Cells, Cultured; Ursolic Acid | 2013 |
Polymethoxy flavonoids, nobiletin and tangeretin, prevent lipopolysaccharide-induced inflammatory bone loss in an experimental model for periodontitis.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Cell Differentiation; Cell Line; Cells, Cultured; Disease Models, Animal; Flavones; Lipopolysaccharides; Mandibular Diseases; Mice; Osteoclasts; Periodontitis | 2012 |
Identification of active compounds from Aurantii Immatri Pericarpium attenuating brain injury in a rat model of ischemia-reperfusion.
Topics: Animals; Apoptosis; Brain Ischemia; Citrus; Disease Models, Animal; DNA Fragmentation; Flavones; Fruit; Hep G2 Cells; Humans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2013 |
Antagonistic effects of nobiletin, a polymethoxyflavonoid, on eosinophilic airway inflammation of asthmatic rats and relevant mechanisms.
Topics: Animals; Anti-Asthmatic Agents; Antioxidants; Apoptosis; Asthma; Bronchitis; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chemokines, CC; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; fas Receptor; Flavones; Injections, Intraperitoneal; Male; Ovalbumin; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Nobiletin restoring beta-amyloid-impaired CREB phosphorylation rescues memory deterioration in Alzheimer's disease model rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cells, Cultured; CREB-Binding Protein; Disease Models, Animal; Flavones; Hippocampus; Memory Disorders; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2006 |