Page last updated: 2024-09-03

nnc 112 and Schizophrenia

nnc 112 has been researched along with Schizophrenia in 5 studies

*Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. [MeSH]

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abi-Dargham, A; Girgis, RR; Poels, EM; Slifstein, M; Thompson, JL1
Fujimura, Y; Ito, H; Kishimoto, T; Kosaka, J; Matsumoto, R; Nozaki, S; Okubo, Y; Suhara, T; Takahashi, H; Takano, A; Yasuno, F1
Abi-Dargham, A; Gil, R; Hwang, DR; Kegeles, LS; Laruelle, M; Narendran, R; Slifstein, M; Thompson, JL; Urban, N; Xu, X1
Abi-Dargham, A; Guo, N; Huang, YY; Hwang, DR; Laruelle, M; Lo, ES1
Abi-Dargham, A; Gil, R; Gorman, JM; Huang, Y; Hwang, DR; Keilp, J; Kochan, L; Laruelle, M; Lombardo, I; Martinez, D; Mawlawi, O; Van Heertum, R1

Trials

1 trial(s) available for nnc 112 and Schizophrenia

ArticleYear
Prefrontal dopamine D1 receptors and working memory in schizophrenia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-01, Volume: 22, Issue:9

    Topics: Adult; Age Factors; Benzazepines; Benzofurans; Binding, Competitive; Carbon Radioisotopes; Dopamine Antagonists; Female; Humans; Magnetic Resonance Imaging; Male; Memory Disorders; Memory, Short-Term; Neuropsychological Tests; Predictive Value of Tests; Prefrontal Cortex; Principal Component Analysis; Receptors, Dopamine D1; Schizophrenia; Tomography, Emission-Computed

2002

Other Studies

4 other study(ies) available for nnc 112 and Schizophrenia

ArticleYear
In vivo binding of the dopamine-1 receptor PET tracers [¹¹C]NNC112 and [¹¹C]SCH23390: a comparison study in individuals with schizophrenia.
    Psychopharmacology, 2013, Volume: 228, Issue:1

    Topics: Adolescent; Adult; Benzazepines; Benzofurans; Carbon Radioisotopes; Case-Control Studies; Female; Humans; Male; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Receptors, Dopamine D1; Schizophrenia; Young Adult

2013
Decreased binding of [11C]NNC112 and [11C]SCH23390 in patients with chronic schizophrenia.
    Life sciences, 2010, May-22, Volume: 86, Issue:21-22

    Topics: Adult; Antipsychotic Agents; Benzazepines; Benzofurans; Brain; Cerebral Cortex; Cognition; Corpus Striatum; Female; Humans; Ligands; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Receptors, Dopamine D1; Schizophrenia

2010
Increased prefrontal cortical D₁ receptors in drug naive patients with schizophrenia: a PET study with [¹¹C]NNC112.
    Journal of psychopharmacology (Oxford, England), 2012, Volume: 26, Issue:6

    Topics: Adult; Antipsychotic Agents; Benzazepines; Benzofurans; Dopamine; Female; Humans; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Prefrontal Cortex; Radiopharmaceuticals; Receptors, Dopamine D1; Schizophrenia; Up-Regulation

2012
Dopamine depletion and in vivo binding of PET D1 receptor radioligands: implications for imaging studies in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:9

    Topics: Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Benzazepines; Benzofurans; Binding Sites; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Antagonists; Enzyme Inhibitors; Hippocampus; Male; Prefrontal Cortex; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reserpine; Schizophrenia; Time Factors; Tritium

2003