Page last updated: 2024-09-05

nk3201 and Disease Models, Animal

nk3201 has been researched along with Disease Models, Animal in 4 studies

*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jin, D; Miyazaki, M; Muramatsu, M; Nishimoto, M; Sakaguchi, M; Sasaki, S; Takai, S; Tsunemi, K; Yuda, A1
Hayashi, T; Inoue, N; Jin, D; Katayama, H; Kitaura, Y; Miyazaki, M; Muramatsu, M; Takai, S; Tamai, H1
Doggrell, SA; Wanstall, JC1
Fukumoto, H; Furubayashi, K; Ibaraki, T; Jin, D; Katsumata, T; Miyazaki, M; Muramatsu, M; Nishimoto, M; Takai, S1

Reviews

1 review(s) available for nk3201 and Disease Models, Animal

ArticleYear
Will chymase inhibitors be the next major development for the treatment of cardiovascular disorders?
    Expert opinion on investigational drugs, 2003, Volume: 12, Issue:8

    Topics: Acetamides; Animals; Azetidines; Benzoates; Cardiovascular Diseases; Chymases; Disease Models, Animal; Humans; Pyrimidines; Serine Endopeptidases; Serine Proteinase Inhibitors; Tunica Intima

2003

Other Studies

3 other study(ies) available for nk3201 and Disease Models, Animal

ArticleYear
A specific chymase inhibitor, 2-(5-formylamino-6-oxo-2-phenyl-1,6-dihydropyrimidine-1-yl)-N-[[3,4-dioxo-1-phenyl-7-(2-pyridyloxy)]-2-heptyl]acetamide (NK3201), suppresses development of abdominal aortic aneurysm in hamsters.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Acetamides; Animals; Aorta; Aortic Aneurysm, Abdominal; Chymases; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Male; Pancreatic Elastase; Pyrimidines; Serine Endopeptidases

2004
Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice.
    Atherosclerosis, 2009, Volume: 204, Issue:2

    Topics: Acetamides; Administration, Oral; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Cholesterol; Chymases; Disease Models, Animal; Enzyme Activation; Enzyme Precursors; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Pyrimidines; Serine Proteinase Inhibitors

2009
The significance of chymase in the progression of abdominal aortic aneurysms in dogs.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:4

    Topics: Acetamides; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Count; Chymases; Disease Models, Animal; Disease Progression; Dogs; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neutrophils; Pyrimidines; Tunica Media; Ultrasonography

2007