Page last updated: 2024-10-19

nitroxyl and Colitis

nitroxyl has been researched along with Colitis in 4 studies

nitroxyl: hydroxamic acid oxidized to nitroxyl free radical
nitroxyl : A nitrogen oxoacid consisting of an oxygen atom double-bonded to an NH group.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
" Here, the antioxidant capacity and protective effects of a new class of chemically modified hetastarch (polynitroxyl starch, or PNS) plus 4-hydroxyl-2,2,6,6-tetramethylpiperidine-N-oxyl (Tempol or TPL) (PNS/TPL) were assessed in a model of colitis."7.71Polynitroxylated starch/TPL attenuates cachexia and increased epithelial permeability associated with TNBS colitis. ( Alexander, JS; Carter, P; Coe, L; Grisham, MB; Hsia, CJ; Liu, JE; Ma, JW; Ma, L; Oshima, T; Park, JH; Specian, R; Trimble, CE, 2002)
" The effects of RNP(O) were determined in mice with dextran sodium sulfate (DSS)-induced colitis and compared with those of low-molecular-weight drugs (4-hydroxyl-2,2,6,6-tetramethylpiperidine-1-oxyl [TEMPOL] or mesalamine)."3.78An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice. ( Matsui, H; Nagasaki, Y; Tomita, T; Vong, LB; Yoshitomi, T, 2012)
" Here, the antioxidant capacity and protective effects of a new class of chemically modified hetastarch (polynitroxyl starch, or PNS) plus 4-hydroxyl-2,2,6,6-tetramethylpiperidine-N-oxyl (Tempol or TPL) (PNS/TPL) were assessed in a model of colitis."3.71Polynitroxylated starch/TPL attenuates cachexia and increased epithelial permeability associated with TNBS colitis. ( Alexander, JS; Carter, P; Coe, L; Grisham, MB; Hsia, CJ; Liu, JE; Ma, JW; Ma, L; Oshima, T; Park, JH; Specian, R; Trimble, CE, 2002)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hossain, MA1
Yamashita, M1
Vong, LB3
Ikeda, Y1
Nagasaki, Y3
Yoshitomi, T2
Matsui, H2
Tomita, T1
Park, JH1
Ma, L1
Oshima, T1
Carter, P1
Coe, L1
Ma, JW1
Specian, R1
Grisham, MB1
Trimble, CE1
Hsia, CJ1
Liu, JE1
Alexander, JS1

Other Studies

4 other studies available for nitroxyl and Colitis

ArticleYear
Silica-installed redox nanoparticles for novel oral nanotherapeutics - improvement in intestinal delivery with anti-inflammatory effects.
    Journal of drug targeting, 2014, Volume: 22, Issue:7

    Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Colitis; Colon; Delayed-Action Pre

2014
Development of an oral nanotherapeutics using redox nanoparticles for treatment of colitis-associated colon cancer.
    Biomaterials, 2015, Volume: 55

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Azoxymethane; Camptothecin; Cell Line, Tumor;

2015
An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice.
    Gastroenterology, 2012, Volume: 143, Issue:4

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Colitis; Colon

2012
Polynitroxylated starch/TPL attenuates cachexia and increased epithelial permeability associated with TNBS colitis.
    Inflammation, 2002, Volume: 26, Issue:1

    Topics: Adult; Animals; Antioxidants; Body Weight; Cachexia; Cell Adhesion; Colitis; Cyclic N-Oxides; Diseas

2002