nitroxyl has been researched along with Brain Edema in 2 studies
nitroxyl: hydroxamic acid oxidized to nitroxyl free radical
nitroxyl : A nitrogen oxoacid consisting of an oxygen atom double-bonded to an NH group.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The metal chelator deferoxamine as well as three nitroxide derivatives, differing in hydrophilicity and charge, and one hydroxylamine (a reduced nitroxide) facilitated the clinical recovery and decreased the brain edema." | 3.70 | Mechanism of brain protection by nitroxide radicals in experimental model of closed-head injury. ( Bass, R; Beit-Yannai, E; Samuni, A; Shohami, E; Trembovler, V; Zhang, R, 1998) |
| "Intracerebral hemorrhage is reported to induce the generation of reactive oxygen species and oxidative DNA damage in the brain." | 1.38 | Redox nanoparticle treatment protects against neurological deficit in focused ultrasound-induced intracerebral hemorrhage. ( Chonpathompikunlert, P; Fan, CH; Nagasaki, Y; Ozaki, Y; Yeh, CK; Yoshitomi, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chonpathompikunlert, P | 1 |
| Fan, CH | 1 |
| Ozaki, Y | 1 |
| Yoshitomi, T | 1 |
| Yeh, CK | 1 |
| Nagasaki, Y | 1 |
| Zhang, R | 1 |
| Shohami, E | 1 |
| Beit-Yannai, E | 1 |
| Bass, R | 1 |
| Trembovler, V | 1 |
| Samuni, A | 1 |
2 other studies available for nitroxyl and Brain Edema
| Article | Year |
|---|---|
Redox nanoparticle treatment protects against neurological deficit in focused ultrasound-induced intracerebral hemorrhage.
Topics: Animals; Antioxidants; Brain; Brain Edema; Cerebral Hemorrhage; DNA; Male; Microbubbles; Nanoparticl | 2012 |
Mechanism of brain protection by nitroxide radicals in experimental model of closed-head injury.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Diseases; Brain Edema; Deferoxamine; Head Injuries | 1998 |