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nitrous oxide and Stroke

nitrous oxide has been researched along with Stroke in 17 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
" We examined the comparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke."9.13The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke. ( Kadoi, Y; Saito, S; Takahashi, K, 2008)
"Preclinical evidence in rodents has suggested that inert gases, such as xenon or nitrous oxide, may be promising neuroprotective agents for treating acute ischemic stroke."7.77Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke. ( Abraini, JH; Colloc'h, N; Colomb, DG; David, HN; Haelewyn, B; Risso, JJ, 2011)
"Nitrous oxide has been associated with increased vascular risk in the perioperative period."6.77Nitrous oxide exposure does not seem to be associated with increased mortality, stroke, and myocardial infarction: a non-randomized subgroup analysis of the General Anaesthesia compared with Local Anaesthesia for carotid surgery (GALA) trial. ( Bodenham, A; Gough, MJ; Graham, C; Lewis, SC; Sanders, RD; Warlow, C, 2012)
"The administration of nitrous oxide was associated with increased long-term risk of myocardial infarction, but not of death or stroke in patients enrolled in the ENIGMA trial."5.15Nitrous oxide and long-term morbidity and mortality in the ENIGMA trial. ( Chan, MT; Forbes, A; Leslie, K; Myles, PS; Paech, MJ; Peyton, P; Silbert, BS; Williamson, E, 2011)
" We examined the comparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke."5.13The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke. ( Kadoi, Y; Saito, S; Takahashi, K, 2008)
" The results of meta-analyses showed that nitrous oxide-based techniques increased the incidence of pulmonary atelectasis (odds ratio (OR) 1."4.91Nitrous oxide-based techniques versus nitrous oxide-free techniques for general anaesthesia. ( Jia, RH; Jia, WQ; Kuriyama, A; Liu, Y; Luo, XF; Ma, B; Sun, R; Tian, JH; Yang, K; Zhang, P, 2015)
"Lubeluzole was developed as a neuroprotective substance for use in acute ischaemic stroke."4.81Nitrous oxide modulator: lubeluzole. ( Diener, HC; Wessel, TC, 2002)
"Preclinical evidence in rodents has suggested that inert gases, such as xenon or nitrous oxide, may be promising neuroprotective agents for treating acute ischemic stroke."3.77Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke. ( Abraini, JH; Colloc'h, N; Colomb, DG; David, HN; Haelewyn, B; Risso, JJ, 2011)
"Nitrous oxide has been associated with increased vascular risk in the perioperative period."2.77Nitrous oxide exposure does not seem to be associated with increased mortality, stroke, and myocardial infarction: a non-randomized subgroup analysis of the General Anaesthesia compared with Local Anaesthesia for carotid surgery (GALA) trial. ( Bodenham, A; Gough, MJ; Graham, C; Lewis, SC; Sanders, RD; Warlow, C, 2012)
"In particular, stroke is a frequent complication associated with atrial fibrillation."1.46Characteristics of the new AtriCure cryoFORM® cryoablation probe for the surgical treatment of cardiac arrhythmias. ( Misfeld, M; Schroeter, T, 2017)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (29.41)29.6817
2010's11 (64.71)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Zhang, L1
Sui, S1
Wang, S1
Sun, J1
Schroeter, T1
Misfeld, M1
Imberger, G1
Orr, A1
Thorlund, K1
Wetterslev, J1
Myles, P1
Møller, AM1
Sun, R1
Jia, WQ1
Zhang, P1
Yang, K1
Tian, JH1
Ma, B1
Liu, Y1
Jia, RH1
Luo, XF1
Kuriyama, A1
Bause, GS1
Hoffmann, U1
Sheng, H1
Ayata, C1
Warner, DS2
Leslie, K1
Myles, PS1
Chan, MT1
Forbes, A1
Paech, MJ1
Peyton, P1
Silbert, BS1
Williamson, E1
Beattie, WS1
Badner, NH1
Haelewyn, B1
David, HN3
Colloc'h, N1
Colomb, DG1
Risso, JJ1
Abraini, JH3
Gauberti, M1
Obiang, P1
Guedin, P1
Balossier, A1
Gakuba, C1
Diependaele, AS1
Chazalviel, L2
Vivien, D1
Young, AR1
Agin, V1
Orset, C1
Basaran, A1
Emre, U1
Karadavut, KI1
Bulmus, N1
Sanders, RD1
Graham, C1
Lewis, SC1
Bodenham, A1
Gough, MJ1
Warlow, C1
Diener, HC1
Wessel, TC1
Leveille, F1
MacKenzie, ET2
Buisson, A2
Lemaire, M2
Nicole, O1
Yokoo, N1
Kadoi, Y1
Saito, S1
Takahashi, K1

Reviews

4 reviews available for nitrous oxide and Stroke

ArticleYear
Does anaesthesia with nitrous oxide affect mortality or cardiovascular morbidity? A systematic review with meta-analysis and trial sequential analysis.
    British journal of anaesthesia, 2014, Volume: 112, Issue:3

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Cardiovascular Diseases; Heart Arrest; Humans; Myoc

2014
Nitrous oxide-based techniques versus nitrous oxide-free techniques for general anaesthesia.
    The Cochrane database of systematic reviews, 2015, Nov-06, Issue:11

    Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Humans; Myocardial Infarction; Nausea; Nitrous

2015
Anesthesia in Experimental Stroke Research.
    Translational stroke research, 2016, Volume: 7, Issue:5

    Topics: Anesthesia; Anesthetics; Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Anima

2016
Nitrous oxide modulator: lubeluzole.
    Current medical research and opinion, 2002, Volume: 18 Suppl 2

    Topics: Aged; Brain Ischemia; Humans; Neuroprotective Agents; Nitrous Oxide; Piperidines; Stroke; Thiazoles

2002

Trials

3 trials available for nitrous oxide and Stroke

ArticleYear
Nitrous oxide and long-term morbidity and mortality in the ENIGMA trial.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:2

    Topics: Aged; Anesthetics, Inhalation; Biomarkers; Cause of Death; Chi-Square Distribution; Female; Follow-U

2011
Nitrous oxide exposure does not seem to be associated with increased mortality, stroke, and myocardial infarction: a non-randomized subgroup analysis of the General Anaesthesia compared with Local Anaesthesia for carotid surgery (GALA) trial.
    British journal of anaesthesia, 2012, Volume: 109, Issue:3

    Topics: Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Endarterectomy, Carotid; Female; Hu

2012
The comparative effects of sevoflurane versus isoflurane on cerebrovascular carbon dioxide reactivity in patients with previous stroke.
    Journal of anesthesia, 2008, Volume: 22, Issue:2

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Flow Velocity; Carbon Di

2008

Other Studies

10 other studies available for nitrous oxide and Stroke

ArticleYear
Neuroprotective Effect of Corosolic Acid Against Cerebral Ischemia-Reperfusion Injury in Experimental Rats.
    Journal of oleo science, 2022, Sep-30, Volume: 71, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Brain Injuries; Brain Ischemia; Cyclooxygenase 2; Cytokines; Dino

2022
Characteristics of the new AtriCure cryoFORM® cryoablation probe for the surgical treatment of cardiac arrhythmias.
    Expert review of medical devices, 2017, Volume: 14, Issue:4

    Topics: Atrial Fibrillation; Catheter Ablation; Cryosurgery; Equipment Design; Humans; Nitrous Oxide; Stroke

2017
Portrayed by Peale, Would "Apoplexy" Haunt Colton's Near-asphyxial Anesthetics?
    Anesthesiology, 2016, Volume: 124, Issue:5

    Topics: Anesthetics; Art; History, 19th Century; Humans; Nitrous Oxide; Stroke

2016
The enigma of ENIGMA-I.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:2

    Topics: Anesthetics, Inhalation; Biomarkers; Cause of Death; Homocysteine; Humans; Myocardial Infarction; Ni

2011
Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke.
    Anesthesiology, 2011, Volume: 115, Issue:5

    Topics: Animals; Binding Sites; Brain; Disease Models, Animal; Isoflurane; Male; N-Methylaspartate; Neuropro

2011
Thrombotic stroke in the anesthetized monkey (Macaca mulatta): characterization by MRI--a pilot study.
    Cerebrovascular diseases (Basel, Switzerland), 2012, Volume: 33, Issue:4

    Topics: Anesthesia; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Atracurium; Craniotomy; Dif

2012
Somatosensory evoked potentials of hand muscles in stroke and their modification by botulinum toxin: a preliminary study.
    Journal of rehabilitation medicine, 2012, Volume: 44, Issue:7

    Topics: Adult; Aged; Analysis of Variance; Botulinum Toxins, Type A; Disability Evaluation; Evoked Potential

2012
Reduction of ischemic brain damage by nitrous oxide and xenon.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:10

    Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Calcium; Cells, Cultured; Excitatory Amino Acid Ag

2003
Neuroprotection by nitrous oxide and xenon and its relation to minimum alveolar concentration.
    Anesthesiology, 2004, Volume: 101, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Infarction, Middle Cerebral Artery; Mice; Neuroprotective Agents;

2004
Postischemic nitrous oxide alone versus intraischemic nitrous oxide in the presence of isoflurane: what it may change for neuroprotection against cerebral stroke in the rat.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Brain Ischemia; Drug Interactions; Isoflurane; N

2005