Page last updated: 2024-10-19

nitrous oxide and Psychomotor Agitation

nitrous oxide has been researched along with Psychomotor Agitation in 10 studies

Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.

Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.

Research Excerpts

ExcerptRelevanceReference
"Intranasal dexmedetomidine and midazolam are equally effective in decreasing anxiety upon separation from parents; however, midazolam is superior in providing satisfactory conditions during mask induction."5.16Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia. ( Akin, A; Aksu, R; Altuntas, R; Bayram, A; Boyaci, A; Esmaoglu, A; Tosun, Z, 2012)
"Despite advances in postoperative pain management, the proportion of patients with moderate to severe postoperative pain is still ranging 20-80%."1.36Independent risk factors for postoperative pain in need of intervention early after awakening from general anaesthesia. ( Brantner, B; Franck, M; Mei, W; Radtke, F; Seeling, M; Spies, C; Wernecke, KD, 2010)
"Sevoflurane was usually administered at high concentrations of up to 7% on induction; after 2 minutes the concentration was reduced."1.35[Sedation with sevoflurane for magnetic resonance imaging in pediatrics: retrospective study of 5864 cases]. ( De Sanctis Briggs, V, 2009)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's4 (40.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mei, W1
Seeling, M1
Franck, M1
Radtke, F1
Brantner, B1
Wernecke, KD1
Spies, C1
De Sanctis Briggs, V1
Faulk, DJ1
Twite, MD1
Zuk, J1
Pan, Z1
Wallen, B1
Friesen, RH1
Apan, A1
AykaƧ, E1
Kazkayasi, M1
Doganci, N1
Tahran, FD1
Akin, A1
Bayram, A1
Esmaoglu, A1
Tosun, Z1
Aksu, R1
Altuntas, R1
Boyaci, A1
Shibata, S1
Shigeomi, S1
Sato, W1
Enzan, K1
Bordes, M1
Cros, AM1
Auerswald, K1
Behrends, K1
Burkhardt, U1
Olthoff, D1
Fiedler, W1
Dubois, MC1
Piat, V1
Constant, I1
Lamblin, O1
Murat, I1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Quality of Recovery Scores in Parturients With Obesity: A Prospective Observational Cohort Study[NCT04988893]140 participants (Actual)Observational2021-08-09Completed
Evaluating Stress Response and Anxiety Score in Paediatric Patients Sedated With Intranasal Dexmedetomidine[NCT04526652]Phase 260 participants (Actual)Interventional2020-12-01Completed
Comparing Intranasal Dexmedetomidine With Oral Midazolam as Premedication for Older Children Undergoing General Anesthesia for Dental Rehabilitation[NCT02250703]Phase 375 participants (Actual)Interventional2014-09-30Completed
Endotracheal Intubation With Sevoflurane in Surgical Pediatric Patients: Incremental Versus High Concentration Inhalation Induction[NCT02429323]100 participants (Actual)Interventional2011-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

University of Michigan Sedation Scale

"Level of sedation at separation from parents and at the time of mask induction will be measured on a scale of 0 to 4 (University of Michigan Sedation Scale)~University of Michigan Sedation Scale:~0 -Awake/Alert~1 -Minimally Sedated: Tired/sleepy, appropriate response to verbal conversation and/or sounds.~2- Moderately Sedated: Somnolent/sleeping, easily aroused with light tactile stimulation.~3 - Deeply Sedated: Deep sleep, arousable only with significant physical stimulation.~4 - Unarousable~Moderately and Deeply sedated: Satisfactory Awake, minimally sedate, unarousable: Unsatisfactory" (NCT02250703)
Timeframe: Day 0:Just before the patient will be brought to the operating room

,
InterventionParticipants (Count of Participants)
Satisfactory sedation on separation from parentsUnsatisfactory sedation on separation from parentsSatisfactory sedation on transfer to OR tableUnsatisfactory sedation on transfer to OR table
Dexmedetomidine25112214
Midazolam15221225

Reviews

1 review available for nitrous oxide and Psychomotor Agitation

ArticleYear
[Inhalation induction with sevoflurane in paediatrics: what is new?].
    Annales francaises d'anesthesie et de reanimation, 2006, Volume: 25, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Drug Synergism;

2006

Trials

4 trials available for nitrous oxide and Psychomotor Agitation

ArticleYear
Hypnotic depth and the incidence of emergence agitation and negative postoperative behavioral changes.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:1

    Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Inhalati

2010
Magnesium sulphate infusion is not effective on discomfort or emergence phenomenon in paediatric adenoidectomy/tonsillectomy.
    International journal of pediatric otorhinolaryngology, 2010, Volume: 74, Issue:12

    Topics: Adenoidectomy; Adolescent; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Combined; A

2010
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:9

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine;

2012
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:9

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine;

2012
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:9

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine;

2012
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
    Paediatric anaesthesia, 2012, Volume: 22, Issue:9

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine;

2012
[Propofol for paediatric patients in ear, nose and throat surgery. Practicability, quality and cost-effectiveness of different anaesthesia procedures for adenoidectomy in infants].
    Der Anaesthesist, 2006, Volume: 55, Issue:8

    Topics: Adenoidectomy; Alfentanil; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation;

2006

Other Studies

5 other studies available for nitrous oxide and Psychomotor Agitation

ArticleYear
Independent risk factors for postoperative pain in need of intervention early after awakening from general anaesthesia.
    European journal of pain (London, England), 2010, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Ge

2010
[Sedation with sevoflurane for magnetic resonance imaging in pediatrics: retrospective study of 5864 cases].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Deep Sedation; Female; Humans; Hypnotics and Sedatives; Infant;

2009
Nitrous oxide administration during washout of sevoflurane improves postanesthetic agitation in children.
    Journal of anesthesia, 2005, Volume: 19, Issue:2

    Topics: Child; Child, Preschool; Electroencephalography; Female; Humans; Male; Methyl Ethers; Nitrous Oxide;

2005
[Experiences with nitrous oxide analgesia in emergency care].
    Zeitschrift fur arztliche Fortbildung, 1984, Volume: 78, Issue:14

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Arousal; Child; Child, Preschool; Drug Therapy, Com

1984
Comparison of three techniques for induction of anaesthesia with sevoflurane in children.
    Paediatric anaesthesia, 1999, Volume: 9, Issue:1

    Topics: Analysis of Variance; Anesthesia, Inhalation; Anesthetics, Inhalation; Blinking; Blood Pressure; Chi

1999