nitrous oxide has been researched along with Pain, Postoperative in 108 studies
Nitrous Oxide: Nitrogen oxide (N2O). A colorless, odorless gas that is used as an anesthetic and analgesic. High concentrations cause a narcotic effect and may replace oxygen, causing death by asphyxia. It is also used as a food aerosol in the preparation of whipping cream.
dinitrogen oxide : A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Effective prophylaxis for postoperative nausea and vomiting can be achieved in adults with lower doses of ondansetron, a 5-hydroxytryptamine subtype 3 receptor antagonist, compared with chemotherapy-induced emesis." | 9.08 | The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery. ( Bras, PJ; Cieslak, GD; Pennant, JH; Watcha, MF, 1995) |
| "Sixty-two patients undergoing LH were randomized to receive either isoflurane-N2O or propofol-N2O anesthesia." | 9.08 | Recovery and outcome after propofol and isoflurane anesthesia in patients undergoing laparoscopic hysterectomy. ( Eriksson, H; Korttila, K; Nelskylä, K; Soikkeli, A, 1997) |
| "There is no difference in intraoperative and postoperative pain between nitrous oxide and carbon dioxide pneumoperitoneum for laparoscopic sterilization when used in conjunction with a protocol such as ours." | 9.07 | The effect of nitrous oxide and carbon dioxide pneumoperitoneum on operative and postoperative pain during laparoscopic sterilization under local anesthesia. ( Ling, FW; Lipscomb, GH; McCord, ML; Summitt, RL, 1994) |
| "Postoperative nausea, postoperative vomiting (PV), or nausea, vomiting, or both (PONV) was assessed in the early (0-4 h) and overall postoperative period (0-24 h) by an anaesthesiologist unaware of patient allocation." | 6.72 | Inspired oxygen fraction of 0.8 compared with 0.4 does not further reduce postoperative nausea and vomiting in dolasetron-treated patients undergoing laparoscopic cholecystectomy. ( Boldt, J; Faust, KL; Kranke, P; Maleck, WH; Piper, SN; Röhm, KD; Suttner, SW, 2006) |
| "There was a trend in the incidence of postoperative nausea (PN): group TD 17%, 95% CI: 8-30%) compared to group VD 31%, 95% CI: 20-46%), p = 0." | 6.71 | [Prophylaxis of postoperative nausea and vomiting (PONV) in children undergoing strabismus surgery. Sevoflurane/N2O plus dimenhydrinate vs.propofol/remifentanil plus dimenhydrinate]. ( Biallas, R; de Decker, W; Rüsch, D; Scholz, J; Siebrecht, D; Wulf, H, 2003) |
| "Postoperative pain was assessed by a blinded observer using an objective pain scale (OPS)." | 6.68 | Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M, 1997) |
| "Administration of 35% N2O significantly reduced hyperalgesia, allodynia and pain intensity induced after remifentanil." | 5.41 | Evaluation of antihyperalgesic and analgesic effects of 35% nitrous oxide when combined with remifentanil: A randomised phase 1 trial in volunteers. ( Bauer, M; Bessiere, B; Ihmsen, H; Noel, N; Prottengeier, J; Ramirez-Gil, JF; Schüttler, J; Wehrfritz, A, 2021) |
| "Intranasal dexmedetomidine and midazolam are equally effective in decreasing anxiety upon separation from parents; however, midazolam is superior in providing satisfactory conditions during mask induction." | 5.16 | Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia. ( Akin, A; Aksu, R; Altuntas, R; Bayram, A; Boyaci, A; Esmaoglu, A; Tosun, Z, 2012) |
| "Our aim was to show the efficacy of naproxen and paracetamol with and without pethidine on pain and nausea and vomiting after adenoidectomy." | 5.12 | Oral naproxen but not oral paracetamol reduces the need for rescue analgesic after adenoidectomy in children. ( Korpela, R; Laakso, E; Meretoja, OA; Silvola, J, 2007) |
| "Women presenting for elective ambulatory termination of pregnancy or gynecologic laparoscopy were induced with an intravenous sleep dose of propofol and fentanyl." | 5.09 | Omission of nitrous oxide from a propofol-based anesthetic does not affect the recovery of women undergoing outpatient gynecologic surgery. ( Arellano, RJ; Chung, FF; Fletcher, M; Friedlander, M; Norris, A; Pole, ML; Rafuse, SE; Saad, YG, 2000) |
| " Effective prophylaxis for postoperative nausea and vomiting can be achieved in adults with lower doses of ondansetron, a 5-hydroxytryptamine subtype 3 receptor antagonist, compared with chemotherapy-induced emesis." | 5.08 | The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery. ( Bras, PJ; Cieslak, GD; Pennant, JH; Watcha, MF, 1995) |
| "Sixty-two patients undergoing LH were randomized to receive either isoflurane-N2O or propofol-N2O anesthesia." | 5.08 | Recovery and outcome after propofol and isoflurane anesthesia in patients undergoing laparoscopic hysterectomy. ( Eriksson, H; Korttila, K; Nelskylä, K; Soikkeli, A, 1997) |
| "There is no difference in intraoperative and postoperative pain between nitrous oxide and carbon dioxide pneumoperitoneum for laparoscopic sterilization when used in conjunction with a protocol such as ours." | 5.07 | The effect of nitrous oxide and carbon dioxide pneumoperitoneum on operative and postoperative pain during laparoscopic sterilization under local anesthesia. ( Ling, FW; Lipscomb, GH; McCord, ML; Summitt, RL, 1994) |
| "Intraoperative anesthetic agent and postoperative pain medication use was recorded." | 2.76 | Nitrous oxide for pneumoperitoneum: no laughing matter this! A prospective single blind case controlled study. ( Manimaran, AB; Manohar, RR; Naidu, RM; Rammohan, A, 2011) |
| "We recorded the severity of postsurgical pain of at least 3 months' duration that was not due to disease recurrence or a pre-existing pain syndrome, using the modified Brief Pain Inventory." | 2.76 | Chronic postsurgical pain after nitrous oxide anesthesia. ( Chan, MTV; Gin, T; Leslie, K; Myles, PS; Wan, ACM, 2011) |
| "Frequency of postoperative nausea and vomiting (PONV), visual analog scale (VAS) pain scores, and patient satisfaction were recorded." | 2.74 | Sevoflurane with or without antiemetic prophylaxis of dexamethasone in spontaneously breathing patients undergoing outpatient anorectal surgery. ( Chia, YY; Fong, WP; Lu, SF; Tan, PH; Wu, JI; Yang, LC, 2009) |
| "Postoperative nausea, postoperative vomiting (PV), or nausea, vomiting, or both (PONV) was assessed in the early (0-4 h) and overall postoperative period (0-24 h) by an anaesthesiologist unaware of patient allocation." | 2.72 | Inspired oxygen fraction of 0.8 compared with 0.4 does not further reduce postoperative nausea and vomiting in dolasetron-treated patients undergoing laparoscopic cholecystectomy. ( Boldt, J; Faust, KL; Kranke, P; Maleck, WH; Piper, SN; Röhm, KD; Suttner, SW, 2006) |
| "There was a trend in the incidence of postoperative nausea (PN): group TD 17%, 95% CI: 8-30%) compared to group VD 31%, 95% CI: 20-46%), p = 0." | 2.71 | [Prophylaxis of postoperative nausea and vomiting (PONV) in children undergoing strabismus surgery. Sevoflurane/N2O plus dimenhydrinate vs.propofol/remifentanil plus dimenhydrinate]. ( Biallas, R; de Decker, W; Rüsch, D; Scholz, J; Siebrecht, D; Wulf, H, 2003) |
| "One patient reported postoperative nausea, and no other side effects were reported." | 2.71 | The effectiveness of continuous epidural infusion of low-dose fentanyl and mepivacaine in perioperative analgesia and hemodynamic control in mastectomy patients. ( Kotake, Y; Matsumoto, M; Morisaki, H; Takeda, J, 2004) |
| "The difference in postoperative pain between the pretreated and posttreated sides was assessed by 4 primary end-points: pain intensity as measured by a 100-mm visual analog scale (VAS) hourly for 8 hours, time to first analgesic, total analgesic consumption during the first 48 hours, and a 5-point categorical patient global assessment scale (0=poor, 1=fair, 2=good, 3=very good, and 4=excellent)." | 2.71 | A prospective randomized crossover study of the preemptive analgesic effect of nitrous oxide in oral surgery. ( Ong, KS; Seymour, RA; Tan, JM, 2004) |
| "Pyloric stenosis is sometimes associated with hemodynamic instability and postoperative apnea." | 2.70 | A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. I. Emergence and recovery profiles. ( Blum, RH; Davis, PJ; Edwards, S; Galinkin, J; Hechtman, D; Henson, LG; Krane, EJ; Kurth, CD; Lynn, AM; Maxwell, L; McGowan, FX; Orr, R; Rabb, MF; Szmuk, P; Yaster, M, 2001) |
| "SSA patients had significantly less postoperative pain than DES patients (P < 0." | 2.70 | Small-dose selective spinal anesthesia for short-duration outpatient laparoscopy: recovery characteristics compared with desflurane anesthesia. ( Henderson, C; Lennox, PH; Martin, L; Mitchell, GW; Vaghadia, H, 2002) |
| "The intensity of postoperative pain was assessed by the patients themselves using an visual analogue pain score scale." | 2.69 | Comparison of N2O and CO2 pneumoperitoneums during laparoscopic cholecystectomy with special reference to postoperative pain. ( Airo, I; Aitola, P; Kaukinen, S; Ylitalo, P, 1998) |
| "Because the intensity of postoperative pain in end-stage kidney insufficiency patients can be modified by the type of received anaesthesia, it was decided to analyze the influence of standardized general anaesthesia on postoperative morphine consumption." | 2.69 | The influence of the type of anaesthesia on postoperative pain after kidney transplantation. ( Lazowski, T, 2000) |
| "Management of postoperative pain and nausea and discharge criteria were standardized." | 2.68 | Midazolam premedication increases sedation but does not prolong discharge times after brief outpatient general anesthesia for laparoscopic tubal sterilization. ( Hussain, A; Richardson, MG; Wu, CL, 1997) |
| "Sevoflurane patients were less likely to have complications during induction (P < 0." | 2.68 | Sevoflurane versus isoflurane: induction and recovery characteristics with single-breath inhaled inductions of anesthesia. ( Conard, PF; Gross, JB; Karsunky, PK; Sloan, MH, 1996) |
| "Postoperative pain was assessed by a blinded observer using an objective pain scale (OPS)." | 2.68 | Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery. ( Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M, 1997) |
| "Esmolol-treated patients also reported less sedation in the first 15 min of recovery than those receiving alfentanil." | 2.67 | Efficacy of esmolol versus alfentanil as a supplement to propofol-nitrous oxide anesthesia. ( Smith, I; Van Hemelrijck, J; White, PF, 1991) |
| "The results have shown that postoperative pain was much lower in the group of patients who had ketamine hydrochloride anaesthesia, what together with increased oxygen saturation during anaesthesia leads to the conclusion that this anaesthesia is appropriate for operations on the veins of the lower limbs because it ensures postoperative analgesia and oxygenation without oxygen inhalation." | 2.66 | [Anesthesia in patients with varicose syndrome]. ( Kujundzić, D; Zanić-Matanić, D, 1989) |
| "Halothane was restarted if the anaesthesia was ineffective." | 2.66 | A new method of analgesia for relief of circumcision pain. ( Andersen, KH, 1989) |
| " We argue for the continued use of trichloroethylene by this technique, because it costs one hundred times less than enflurane and because of the potential morbidity of the postoperative opiate dosage required after enflurane." | 2.66 | Comparison of trichloroethylene and enflurane as adjuncts to nitrous oxide and relaxant anaesthesia. ( Reynolds, F; Rice, AS, 1987) |
| "However, higher postoperative pain scores were recorded in these patients as well as a higher incidence of nausea and vomiting." | 2.64 | Antagonism of fentanyl with naloxone during N2O+O2+ halothane anaesthesia. ( Tigerstedt, I, 1977) |
| "Nitrous oxide inhalation has also been found to enhance the level of sensory spinal block." | 1.40 | The effects of intrathecal and systemic adjuvants on subarachnoid block. ( Paraskeva, A; Staikou, C, 2014) |
| "6." | 1.36 | Independent risk factors for postoperative pain in need of intervention early after awakening from general anaesthesia. ( Brantner, B; Franck, M; Mei, W; Radtke, F; Seeling, M; Spies, C; Wernecke, KD, 2010) |
| "Diffusion hypoxia which could lead to hypoxemia was reported in 1955, but recent work does not confirm this complication." | 1.30 | [Analgesia using a (50/50) mixture of nitrous oxide/oxygen in children]. ( Carbajal, R, 1999) |
| "Alfentanil is a suitable analgesic drug for nitrous oxide-supplemented intravenous anaesthesia in day case surgery--provided that the appropriate requirements are taken into consideration." | 1.29 | [Relevance of alfentanil as an analgesic in N20 supplemented intravenous anesthesia in ambulatory surgery]. ( Laufer, M; Olthoff, D; Pöhlchen, W, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (23.15) | 18.7374 |
| 1990's | 33 (30.56) | 18.2507 |
| 2000's | 30 (27.78) | 29.6817 |
| 2010's | 19 (17.59) | 24.3611 |
| 2020's | 1 (0.93) | 2.80 |
| Authors | Studies |
|---|---|
| Wehrfritz, A | 1 |
| Bauer, M | 1 |
| Noel, N | 1 |
| Ramirez-Gil, JF | 1 |
| Ihmsen, H | 1 |
| Prottengeier, J | 1 |
| Schüttler, J | 1 |
| Bessiere, B | 1 |
| Canto, MI | 1 |
| Abrams, JA | 1 |
| Künzli, HT | 1 |
| Weusten, B | 1 |
| Komatsu, Y | 1 |
| Jobe, BA | 1 |
| Lightdale, CJ | 1 |
| Jebali, C | 1 |
| Boukadida, L | 1 |
| Ousgi, A | 1 |
| Chaabene, W | 1 |
| Shili, B | 1 |
| Naggara, MA | 1 |
| Boukef, R | 1 |
| Dai, YL | 1 |
| Chai, XM | 1 |
| Zhu, N | 1 |
| Wang, KB | 1 |
| Bao, WQ | 1 |
| Zhang, XS | 1 |
| Gao, LL | 1 |
| Liu, Q | 1 |
| Bao, DM | 1 |
| Wang, LT | 1 |
| Wang, YL | 1 |
| Zhang, JJ | 1 |
| Li, YX | 1 |
| Yu, JQ | 1 |
| Drosner, M | 1 |
| de Vasconcellos, K | 1 |
| Sneyd, JR | 1 |
| Staikou, C | 1 |
| Paraskeva, A | 1 |
| Chan, MT | 2 |
| Gin, T | 2 |
| Ramanadham, SR | 1 |
| Costa, CR | 1 |
| Narasimhan, K | 1 |
| Coleman, JE | 1 |
| Rohrich, RJ | 1 |
| Oliveira, G | 1 |
| Lokhande, C | 1 |
| Riad, I | 1 |
| Tetzlaff, J | 1 |
| Ayad, S | 1 |
| Kim, MK | 1 |
| Yi, MS | 1 |
| Kang, H | 1 |
| Choi, GJ | 1 |
| Peyton, PJ | 1 |
| Myles, PS | 2 |
| Leslie, K | 2 |
| Buckley, N | 1 |
| Kasza, J | 1 |
| Paech, MJ | 1 |
| Beattie, WS | 1 |
| Sessler, DI | 1 |
| Forbes, A | 1 |
| Wallace, S | 1 |
| Chen, Y | 1 |
| Tian, Y | 1 |
| Wu, WK | 1 |
| Mei, W | 1 |
| Seeling, M | 1 |
| Franck, M | 1 |
| Radtke, F | 1 |
| Brantner, B | 1 |
| Wernecke, KD | 1 |
| Spies, C | 1 |
| Brown, SC | 1 |
| Hart, G | 1 |
| Chastain, DP | 1 |
| Schneeweiss, S | 1 |
| McGrath, PA | 1 |
| Wu, JI | 1 |
| Lu, SF | 1 |
| Chia, YY | 1 |
| Yang, LC | 1 |
| Fong, WP | 1 |
| Tan, PH | 1 |
| Stiglitz, DK | 1 |
| Amaratunge, LN | 1 |
| Konstantatos, AH | 1 |
| Lindholm, DE | 1 |
| Rammohan, A | 1 |
| Manimaran, AB | 1 |
| Manohar, RR | 1 |
| Naidu, RM | 1 |
| Chan, MTV | 1 |
| Wan, ACM | 1 |
| Echevarría, G | 1 |
| Elgueta, F | 1 |
| Fierro, C | 1 |
| Bugedo, D | 1 |
| Faba, G | 1 |
| Iñiguez-Cuadra, R | 1 |
| Muñoz, HR | 1 |
| Cortínez, LI | 1 |
| Akin, A | 1 |
| Bayram, A | 1 |
| Esmaoglu, A | 1 |
| Tosun, Z | 1 |
| Aksu, R | 1 |
| Altuntas, R | 1 |
| Boyaci, A | 1 |
| Martinez, V | 1 |
| Fletcher, D | 1 |
| Sanders, J | 1 |
| Campbell, R | 1 |
| Peters, TJ | 1 |
| Jones, JS | 1 |
| Manikandan, R | 1 |
| Collins, GN | 1 |
| Wilder-Smith, OH | 2 |
| Tassonyi, E | 2 |
| Crul, BJ | 1 |
| Arendt-Nielsen, L | 2 |
| Orii, R | 1 |
| Ohashi, Y | 1 |
| Halder, S | 1 |
| Giombini, M | 1 |
| Maze, M | 1 |
| Fujinaga, M | 1 |
| Hamad, MA | 1 |
| El-Khattary, OA | 1 |
| Biallas, R | 1 |
| Rüsch, D | 1 |
| de Decker, W | 1 |
| Wulf, H | 1 |
| Siebrecht, D | 1 |
| Scholz, J | 1 |
| PARBROOK, GD | 2 |
| REES, GA | 1 |
| ROBERTSON, GS | 1 |
| KENNEDY, BR | 1 |
| HART, D | 1 |
| Laberg, GO | 1 |
| Leirvåg, JP | 1 |
| Leeuwenberg, J | 1 |
| Bergamaschi, R | 1 |
| Naidu, S | 1 |
| Loughlin, P | 1 |
| Coldwell, SE | 1 |
| Noonan, CJ | 1 |
| Milgrom, P | 1 |
| Kotake, Y | 1 |
| Matsumoto, M | 1 |
| Morisaki, H | 1 |
| Takeda, J | 1 |
| Doran, M | 1 |
| Rassam, SS | 1 |
| Jones, LM | 1 |
| Underhill, S | 1 |
| Reurer, M | 1 |
| Hueppe, M | 1 |
| Klotz, KF | 1 |
| Beckhoff, M | 1 |
| Hennig, J | 1 |
| Netter, P | 1 |
| Schmucker, P | 1 |
| Ong, KS | 1 |
| Seymour, RA | 1 |
| Tan, JM | 1 |
| Luginbühl, M | 1 |
| Petersen-Felix, S | 1 |
| Zbinden, AM | 1 |
| Schnider, TW | 1 |
| Roelofse, JA | 1 |
| Shipton, EA | 1 |
| de la Harpe, CJ | 1 |
| Blignaut, RJ | 1 |
| Lee, LH | 1 |
| Irwin, MG | 1 |
| Lui, SK | 1 |
| Long, JA | 1 |
| Manel, A | 1 |
| Moalic, R | 1 |
| Pellat, JM | 1 |
| Boillot, B | 1 |
| Descotes, JL | 1 |
| Rambeaud, JJ | 1 |
| Chung, F | 1 |
| Kayumov, L | 1 |
| Sinclair, DR | 1 |
| Edward, R | 1 |
| Moller, HJ | 1 |
| Shapiro, CM | 1 |
| Piper, SN | 1 |
| Röhm, KD | 1 |
| Boldt, J | 1 |
| Faust, KL | 1 |
| Maleck, WH | 1 |
| Kranke, P | 1 |
| Suttner, SW | 1 |
| Nishikawa, K | 1 |
| Kimura, S | 1 |
| Shimodate, Y | 1 |
| Igarashi, M | 1 |
| Namiki, A | 1 |
| Korpela, R | 1 |
| Silvola, J | 1 |
| Laakso, E | 1 |
| Meretoja, OA | 1 |
| Mathews, DM | 1 |
| Gaba, V | 1 |
| Zaku, B | 1 |
| Neuman, GG | 1 |
| Yoo, KY | 1 |
| Jeong, CW | 1 |
| Kang, MW | 1 |
| Kim, SJ | 1 |
| Chung, ST | 1 |
| Shin, MH | 1 |
| Lee, J | 1 |
| Torda, TA | 1 |
| Kripke, BJ | 1 |
| Justice, RE | 1 |
| Hechtman, HB | 1 |
| Jørgensen, BC | 1 |
| Andersen, HB | 1 |
| Engquist, A | 1 |
| Levine, JD | 1 |
| Gordon, NC | 1 |
| Fields, HL | 1 |
| Watcha, MF | 1 |
| Bras, PJ | 1 |
| Cieslak, GD | 1 |
| Pennant, JH | 1 |
| Hendolin, H | 1 |
| Kansanen, M | 1 |
| Koski, E | 1 |
| Nuutinen, J | 1 |
| Laufer, M | 1 |
| Olthoff, D | 1 |
| Pöhlchen, W | 1 |
| Moore, WJ | 1 |
| Underwood, S | 1 |
| Krogh, B | 1 |
| Jørn Jensen, P | 1 |
| Henneberg, SW | 1 |
| Hole, P | 1 |
| Kronborg, O | 1 |
| Abram, SE | 1 |
| Yaksh, TL | 1 |
| Jellish, WS | 1 |
| Lien, CA | 1 |
| Fontenot, HJ | 1 |
| Hall, R | 1 |
| Sloan, MH | 1 |
| Conard, PF | 1 |
| Karsunky, PK | 1 |
| Gross, JB | 1 |
| Senly, C | 1 |
| Otten, P | 1 |
| Gupta, A | 1 |
| Danielson, A | 1 |
| Heath, KJ | 1 |
| Sadler, P | 1 |
| Winn, JH | 1 |
| McFadzean, WA | 1 |
| Nagai, H | 1 |
| Noda, Y | 1 |
| Mase, K | 1 |
| Ogawa, S | 1 |
| Suzuki, H | 1 |
| Mikawa, K | 1 |
| Nishina, K | 1 |
| Maekawa, N | 1 |
| Shiga, M | 1 |
| Obara, H | 1 |
| Lipscomb, GH | 1 |
| Summitt, RL | 1 |
| McCord, ML | 1 |
| Ling, FW | 1 |
| Nelskylä, K | 1 |
| Eriksson, H | 1 |
| Soikkeli, A | 1 |
| Korttila, K | 2 |
| Richardson, MG | 1 |
| Wu, CL | 1 |
| Hussain, A | 1 |
| Roetman, KJ | 1 |
| Welborn, LG | 1 |
| Hannallah, RS | 1 |
| Fink, R | 1 |
| Norden, JM | 1 |
| O'Donnell, R | 1 |
| Fournier, R | 1 |
| Van Gessel, E | 1 |
| Gaggero, G | 1 |
| Boccovi, S | 1 |
| Forster, A | 1 |
| Gamulin, Z | 1 |
| Aitola, P | 1 |
| Airo, I | 1 |
| Kaukinen, S | 1 |
| Ylitalo, P | 1 |
| Fujii, Y | 1 |
| Toyooka, H | 1 |
| Tanaka, H | 1 |
| Fredman, B | 1 |
| Zohar, E | 1 |
| Philipov, A | 1 |
| Olsfanger, D | 1 |
| Shalev, M | 1 |
| Jedeikin, R | 1 |
| Viitanen, H | 1 |
| Tarkkila, P | 1 |
| Mennander, S | 1 |
| Viitanen, M | 1 |
| Annila, P | 1 |
| Rose, JB | 1 |
| Cuy, R | 1 |
| Cohen, DE | 1 |
| Schreiner, MS | 1 |
| Da Conceicao, MJ | 1 |
| Coelho, L | 1 |
| Khalil, M | 1 |
| Zerafa, M | 1 |
| Baulch, S | 1 |
| Elliott, MJ | 1 |
| Petros, AJ | 1 |
| Randhawa, NA | 1 |
| Bapat, PP | 1 |
| Carbajal, R | 1 |
| Han, T | 1 |
| Kim, D | 1 |
| Kil, H | 1 |
| Inagaki, Y | 1 |
| Lazowski, T | 1 |
| Arellano, RJ | 1 |
| Pole, ML | 1 |
| Rafuse, SE | 1 |
| Fletcher, M | 1 |
| Saad, YG | 1 |
| Friedlander, M | 1 |
| Norris, A | 1 |
| Chung, FF | 1 |
| Davis, PJ | 2 |
| Galinkin, J | 1 |
| McGowan, FX | 1 |
| Lynn, AM | 1 |
| Yaster, M | 1 |
| Rabb, MF | 1 |
| Krane, EJ | 1 |
| Kurth, CD | 1 |
| Blum, RH | 1 |
| Maxwell, L | 1 |
| Orr, R | 1 |
| Szmuk, P | 1 |
| Hechtman, D | 1 |
| Edwards, S | 1 |
| Henson, LG | 1 |
| Lennox, PH | 1 |
| Vaghadia, H | 1 |
| Henderson, C | 1 |
| Martin, L | 1 |
| Mitchell, GW | 1 |
| Utting, JE | 1 |
| Smith, JM | 1 |
| Wallace, PG | 1 |
| Norris, W | 1 |
| Tigerstedt, I | 1 |
| Keeri-Szanto, M | 1 |
| Dalrymple, DG | 1 |
| Parbrock, GD | 1 |
| Fry, EN | 1 |
| Kurbanov, ChIu | 1 |
| Dustbaev, AD | 1 |
| Cade, L | 1 |
| Ross, AW | 1 |
| Smith, I | 1 |
| Van Hemelrijck, J | 1 |
| White, PF | 1 |
| Block, RI | 1 |
| Ghoneim, MM | 1 |
| Sum Ping, ST | 1 |
| Ali, MA | 1 |
| Mulroy, JJ | 1 |
| Rymer, DB | 1 |
| Chaitoff, KA | 1 |
| Boston, JR | 1 |
| Westman, HR | 1 |
| Cook, DR | 1 |
| Lampe, GH | 1 |
| Wauk, LZ | 1 |
| Donegan, JH | 1 |
| Pitts, LH | 1 |
| Jackler, RK | 1 |
| Litt, LL | 1 |
| Rampil, IJ | 1 |
| Eger, EI | 1 |
| Saint-Raymond, S | 1 |
| O'Donovan, F | 1 |
| Ecoffey, C | 1 |
| Zanić-Matanić, D | 1 |
| Kujundzić, D | 1 |
| Glenski, JA | 1 |
| Friesen, RH | 1 |
| Lane, GA | 1 |
| Young, S | 1 |
| Glascock, J | 1 |
| Andersen, KH | 1 |
| Clark, NJ | 1 |
| Meuleman, T | 1 |
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| Ishikawa, M | 1 |
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| Furukawa, K | 1 |
| Takahashi, M | 1 |
| Rice, AS | 1 |
| Reynolds, F | 1 |
| Dworkin, SF | 1 |
| Schubert, M | 1 |
| Chen, AC | 1 |
| Clark, DW | 1 |
| Goddard, JM | 1 |
| Paravicini, D | 1 |
| Trauner, K | 1 |
| Lawin, P | 1 |
| Dobkin, AB | 1 |
| Eamkaow, S | 1 |
| Zak, S | 1 |
| Caruso, FK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Large, Randomised, Parallel-group, Controlled Trial, With Patients Randomly Allocated to Either N2O-containing (70% N2O in Oxygen [FiO2 0.3]) or N2O-free (70% Nitrogen in Oxygen [FiO2 0.3]).[NCT00430989] | Phase 4 | 7,112 participants (Actual) | Interventional | 2007-04-30 | Completed | ||
| Quality of Recovery Scores in Parturients With Obesity: A Prospective Observational Cohort Study[NCT04988893] | 140 participants (Actual) | Observational | 2021-08-09 | Completed | |||
| Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543] | 90 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| Evaluating the Incidence and Association Between Nitrous Oxide and Postoperative Cognitive Disorders in Anaesthesia[NCT02489097] | Phase 4 | 140 participants (Actual) | Interventional | 2013-09-30 | Terminated (stopped due to Interim analysis results showed futility) | ||
| Administration of Acetazolamide to Prevent Remifentanil Induced Hyperalgesia: Randomize Double Blind Clinical Trial[NCT02992938] | Phase 4 | 50 participants (Actual) | Interventional | 2016-12-31 | Completed | ||
| Evaluating Stress Response and Anxiety Score in Paediatric Patients Sedated With Intranasal Dexmedetomidine[NCT04526652] | Phase 2 | 60 participants (Actual) | Interventional | 2020-12-01 | Completed | ||
| Comparing Intranasal Dexmedetomidine With Oral Midazolam as Premedication for Older Children Undergoing General Anesthesia for Dental Rehabilitation[NCT02250703] | Phase 3 | 75 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| Anxiolysis for Emergency Department Procedures in Pediatric Patients Using Intranasal Ketamine Compared With Intranasal Midazolam: A Randomized Controlled Trial[NCT03043430] | Phase 4 | 10 participants (Actual) | Interventional | 2016-05-31 | Terminated (stopped due to Research manpower shortage) | ||
| Randomized, Double-Blind, Placebo-Controlled Trial of Alvimopan in Major Spine Surgery[NCT02789111] | Phase 4 | 49 participants (Actual) | Interventional | 2016-06-01 | Completed | ||
| Effect of Remifentanil on the Recovery Profile After Prolonged Head and Neck Surgery[NCT02416752] | 222 participants (Actual) | Observational | 2011-08-31 | Completed | |||
| The Comparison of Total Intravenous Anesthesia and Inhalation Anesthesia Procedures Used in Oral and Maxillofacial Surgeries in View of Postoperative Complications and the Recovery Period[NCT03187717] | 583 participants (Actual) | Observational | 2016-01-01 | Completed | |||
| A Prospective Randomized Double-blind Placebo Controlled Trial; Does Pre and Postoperative Dextromethorphan Reduce Post-tonsillectomy Pain in Children?[NCT02727491] | Phase 4 | 85 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| Fast-track Laparoscopic Surgery. The Effect of Anesthetic Technique[NCT01275911] | 40 participants (Actual) | Interventional | 2009-01-31 | Completed | |||
| The Power of Healing Statements on Post Operative Pain Control: A Randomized Controlled Trial[NCT02502357] | 32 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Study of the Effect of Intraoperative Positive Messages on Postoperative Outcomes[NCT02765750] | 5 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to The primary investigator was transferred to another hospital) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00430989)
Timeframe: 30 days
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 15 |
| N2O Free Group (FiO2 0.3) | 19 |
(NCT00430989)
Timeframe: 30 Days Post Op
| Intervention | Days (Median) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 6.1 |
| N2O Free Group (FiO2 0.3) | 6.1 |
(NCT00430989)
Timeframe: 30 days post op
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 215 |
| N2O Free Group (FiO2 0.3) | 219 |
(NCT00430989)
Timeframe: 30 Days Post op
| Intervention | participants (Number) |
|---|---|
| N2O Group (FiO2 0.3) | 18 |
| N2O Free Group (FiO2 0.3) | 22 |
(NCT00430989)
Timeframe: 30 Days Post op
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 26 |
| N2O Free Group (FiO2 0.3) | 19 |
(NCT00430989)
Timeframe: 30 days post op
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 283 |
| N2O Free Group (FiO2 0.3) | 296 |
(NCT00430989)
Timeframe: 30 Days Post op
| Intervention | participants (Number) |
|---|---|
| Nitrous Oxide: 70% N2O (FiO2 0.3) | 321 |
| N2O Free Group (FiO2 0.3) | 311 |
"Level of sedation at separation from parents and at the time of mask induction will be measured on a scale of 0 to 4 (University of Michigan Sedation Scale)~University of Michigan Sedation Scale:~0 -Awake/Alert~1 -Minimally Sedated: Tired/sleepy, appropriate response to verbal conversation and/or sounds.~2- Moderately Sedated: Somnolent/sleeping, easily aroused with light tactile stimulation.~3 - Deeply Sedated: Deep sleep, arousable only with significant physical stimulation.~4 - Unarousable~Moderately and Deeply sedated: Satisfactory Awake, minimally sedate, unarousable: Unsatisfactory" (NCT02250703)
Timeframe: Day 0:Just before the patient will be brought to the operating room
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Satisfactory sedation on separation from parents | Unsatisfactory sedation on separation from parents | Satisfactory sedation on transfer to OR table | Unsatisfactory sedation on transfer to OR table | |
| Dexmedetomidine | 25 | 11 | 22 | 14 |
| Midazolam | 15 | 22 | 12 | 25 |
time to first bowel movement after surgery (NCT02789111)
Timeframe: Time to event( up to 7 days); From date of day of surgery until the date of first documented bowel movement
| Intervention | hours (Mean) |
|---|---|
| Alvimopan | 50 |
| Placebo | 64 |
time to resumption oral intake after surgery (NCT02789111)
Timeframe: time to event ( up to 7 days); From date of day of surgery until the date of first documented PO intake
| Intervention | hours (Median) |
|---|---|
| Placebo | 17 |
| Alvimopan | 14.5 |
3 reviews available for nitrous oxide and Pain, Postoperative
| Article | Year |
|---|---|
Nitrous oxide: are we still in equipoise? A qualitative review of current controversies.
Topics: Analgesics, Non-Narcotic; Anesthetics, Inhalation; Cardiovascular Diseases; Humans; Intraoperative A | 2013 |
Postoperative analgesia.
Topics: Administration, Oral; Analgesics, Opioid; Anesthesia, Epidural; Anti-Inflammatory Agents, Non-Steroi | 1979 |
The management of postoperative pain.
Topics: Abdomen; Acupuncture Therapy; Administration, Oral; Age Factors; Aged; Analgesics; Anesthesia, Epidu | 1975 |
63 trials available for nitrous oxide and Pain, Postoperative
| Article | Year |
|---|---|
Evaluation of antihyperalgesic and analgesic effects of 35% nitrous oxide when combined with remifentanil: A randomised phase 1 trial in volunteers.
Topics: Analgesics, Opioid; Double-Blind Method; Healthy Volunteers; Humans; Hyperalgesia; Male; Nitrous Oxi | 2021 |
Inhaled nitrous oxide during the make stitches : Randomized double blind prospective study.
Topics: Administration, Inhalation; Adult; Analgesia; Analgesics, Non-Narcotic; Double-Blind Method; Female; | 2017 |
Analgesia effect of premixed nitrous oxide/oxygen during the rehabilitation after total knee arthroplasty: a study protocol for a randomized controlled trial.
Topics: Aged; Analgesics, Non-Narcotic; Arthralgia; Arthritis; Arthroplasty, Replacement, Knee; China; Doubl | 2019 |
[Nitrous oxide - oxygen analgesia in aesthetic dermatology].
Topics: Administration, Inhalation; Adult; Anesthetics, Inhalation; Dermatologic Surgical Procedures; Female | 2013 |
Chronic postsurgical pain in the Evaluation of Nitrous Oxide in the Gas Mixture for Anaesthesia (ENIGMA)-II trial.
Topics: Aged; Aged, 80 and over; Anesthesia; Anesthetics, Inhalation; Chronic Pain; Female; Hong Kong; Human | 2016 |
Reducing distress for children during invasive procedures: randomized clinical trial of effectiveness of the PediSedate.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Child; Child, Preschool; Emergency Service, Hospita | 2009 |
Sevoflurane with or without antiemetic prophylaxis of dexamethasone in spontaneously breathing patients undergoing outpatient anorectal surgery.
Topics: Adult; Ambulatory Surgical Procedures; Anal Canal; Anesthesia, General; Anesthetics, Inhalation; Ant | 2009 |
Nitrous oxide for pneumoperitoneum: no laughing matter this! A prospective single blind case controlled study.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Blood Pressure; Carbon Dioxide; Female; Heart Rate; Humans; H | 2011 |
Chronic postsurgical pain after nitrous oxide anesthesia.
Topics: Aged; Anesthetics, Inhalation; Chronic Pain; Female; Follow-Up Studies; Humans; Male; Middle Aged; N | 2011 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Quantitative sensory testing and human surgery: effects of analgesic management on postoperative neuroplasticity.
Topics: Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Fentanyl; Humans; | 2003 |
[Prophylaxis of postoperative nausea and vomiting (PONV) in children undergoing strabismus surgery. Sevoflurane/N2O plus dimenhydrinate vs.propofol/remifentanil plus dimenhydrinate].
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2003 |
[Do short-term duration drugs for anaesthesia give postoperative advantages compared to traditional drugs?].
Topics: Anesthetics, Intravenous; Cost-Benefit Analysis; Double-Blind Method; Drug Costs; Female; Fentanyl; | 2003 |
A randomized controlled trial comparing mandibular local anesthesia techniques in children receiving nitrous oxide-oxygen sedation.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Child; Dental Care for Children; Double-B | 2004 |
The effectiveness of continuous epidural infusion of low-dose fentanyl and mepivacaine in perioperative analgesia and hemodynamic control in mastectomy patients.
Topics: Analgesia, Epidural; Anesthesia, General; Anesthetics, Combined; Anesthetics, Inhalation; Anesthetic | 2004 |
A prospective randomized crossover study of the preemptive analgesic effect of nitrous oxide in oral surgery.
Topics: Adolescent; Adult; Analgesics; Anesthesia, Dental; Anesthetics, Inhalation; Anesthetics, Local; Area | 2004 |
Xenon does not reduce opioid requirement for orthopedic surgery.
Topics: Adult; Alfentanil; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Desflurane; | 2005 |
Intranasal sufentanil/midazolam versus ketamine/midazolam for analgesia/sedation in the pediatric population prior to undergoing multiple dental extractions under general anesthesia: a prospective, double-blind, randomized comparison.
Topics: Administration, Intranasal; Analgesics; Anesthesia, Dental; Anesthesia, General; Anesthetics, Combin | 2004 |
Intraoperative remifentanil infusion does not increase postoperative opioid consumption compared with 70% nitrous oxide.
Topics: Adult; Aged; Analgesics, Opioid; Chi-Square Distribution; Colorectal Surgery; Female; Humans; Intrao | 2005 |
Intraoperative remifentanil infusion does not increase postoperative opioid consumption compared with 70% nitrous oxide.
Topics: Adult; Aged; Analgesics, Opioid; Chi-Square Distribution; Colorectal Surgery; Female; Humans; Intrao | 2005 |
Intraoperative remifentanil infusion does not increase postoperative opioid consumption compared with 70% nitrous oxide.
Topics: Adult; Aged; Analgesics, Opioid; Chi-Square Distribution; Colorectal Surgery; Female; Humans; Intrao | 2005 |
Intraoperative remifentanil infusion does not increase postoperative opioid consumption compared with 70% nitrous oxide.
Topics: Adult; Aged; Analgesics, Opioid; Chi-Square Distribution; Colorectal Surgery; Female; Humans; Intrao | 2005 |
[Use of MEOPA (nitrogen monoxide-oxygen mixture) as analgesic for prostate biopsies].
Topics: Analgesics; Anesthetics, Local; Biopsy, Needle; Drug Combinations; Humans; Lidocaine; Male; Nitrous | 2004 |
Inspired oxygen fraction of 0.8 compared with 0.4 does not further reduce postoperative nausea and vomiting in dolasetron-treated patients undergoing laparoscopic cholecystectomy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Inhalation; Antiemetics; Cholecystectomy, L | 2006 |
A comparison of intravenous-based and epidural-based techniques for anesthesia and postoperative analgesia in elderly patients undergoing laparoscopic cholecystectomy.
Topics: Adjuvants, Anesthesia; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesi | 2007 |
Oral naproxen but not oral paracetamol reduces the need for rescue analgesic after adenoidectomy in children.
Topics: Acetaminophen; Adenoidectomy; Administration, Inhalation; Administration, Oral; Analgesics; Anti-Inf | 2007 |
Can remifentanil replace nitrous oxide during anesthesia for ambulatory orthopedic surgery with desflurane and fentanyl?
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Anesthetics, Combined; Anesthetics, Inhalation; A | 2008 |
Bispectral index values during sevoflurane-nitrous oxide general anesthesia in women undergoing cesarean delivery: a comparison between women with and without prior labor.
Topics: Adult; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Apgar Score; Blood Pressure; Brain; | 2008 |
Influence of epidural morphine on postoperative pain, endocrine-metabolic, and renal responses to surgery. A controlled study.
Topics: Adult; Anesthesia, General; Blood Glucose; Double-Blind Method; Epidural Space; Female; Halothane; H | 1982 |
The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Child; Child, Preschool; Dose-Response Relation | 1995 |
Propofol-nitrous oxide versus thiopentone-isoflurane-nitrous oxide anaesthesia for uvulopalatopharyngoplasty in patients with sleep apnea.
Topics: Adult; Anesthesia, General; Anesthetics; Female; Humans; Isoflurane; Male; Middle Aged; Nitrous Oxid | 1994 |
Propofol as sole agent for paediatric day-case dental surgery. A randomised study comparing an intravenous propofol infusion with 100% inspired oxygen versus a nitrous oxide/oxygen/halothane maintenance technique.
Topics: Anesthesia, Dental; Anesthesia, Intravenous; Child; Child, Preschool; Female; Halothane; Humans; Mal | 1994 |
Nitrous oxide does not influence operating conditions or postoperative course in colonic surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Colon; Female; Gastrointestinal Motility; Human | 1994 |
The comparative effects of sevoflurane versus propofol in the induction and maintenance of anesthesia in adult patients.
Topics: Adult; Analgesia; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anest | 1996 |
Sevoflurane versus isoflurane: induction and recovery characteristics with single-breath inhaled inductions of anesthesia.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inh | 1996 |
Surgical pain is followed not only by spinal sensitization but also by supraspinal antinociception.
Topics: Adult; Analgesics, Opioid; Anesthetics, Inhalation; Double-Blind Method; Electric Stimulation; Femal | 1996 |
Nitrous oxide reduces the cost of intravenous anaesthesia.
Topics: Adult; Alfentanil; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthe | 1996 |
Dose-response of flurbiprofen on postoperative pain and emesis after paediatric strabismus surgery.
Topics: Analgesics; Anesthesia, Inhalation; Anesthetics, Inhalation; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
The effect of nitrous oxide and carbon dioxide pneumoperitoneum on operative and postoperative pain during laparoscopic sterilization under local anesthesia.
Topics: Administration, Oral; Adult; Alfentanil; Analgesia; Analgesics, Opioid; Anesthesia, Local; Anestheti | 1994 |
Recovery and outcome after propofol and isoflurane anesthesia in patients undergoing laparoscopic hysterectomy.
Topics: Adult; Anesthesia; Anesthesia Recovery Period; Anesthetics, Intravenous; Female; Humans; Hysterectom | 1997 |
Midazolam premedication increases sedation but does not prolong discharge times after brief outpatient general anesthesia for laparoscopic tubal sterilization.
Topics: Adult; Age Factors; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; | 1997 |
Evaluation of awakening and recovery characteristics following anaesthesia with nitrous oxide and halothane fentanyl or both for brief outpatient procedures in infants.
Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Inha | 1997 |
Postoperative analgesia with "3-in-1" femoral nerve block after prosthetic hip surgery.
Topics: Adjuvants, Anesthesia; Aged; Analgesia; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhala | 1998 |
Comparison of N2O and CO2 pneumoperitoneums during laparoscopic cholecystectomy with special reference to postoperative pain.
Topics: Acidosis, Respiratory; Adrenergic Agonists; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioi | 1998 |
Efficacy of thoracic epidural analgesia following laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Analysis of Variance; Anesthesia, Inhalation; | 1998 |
The induction, maintenance, and recovery characteristics of spinal versus general anesthesia in elderly patients.
Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Spinal; Anesth | 1998 |
Sevoflurane-maintained anesthesia induced with propofol or sevoflurane in small children: induction and recovery characteristics.
Topics: Adenoidectomy; Ambulatory Surgical Procedures; Analgesics; Anesthesia Recovery Period; Anesthesia, G | 1999 |
Preoperative oral dextromethorphan does not reduce pain or analgesic consumption in children after adenotonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Analgesia; Analgesics; Anesthesia Recovery Perio | 1999 |
Ropivacaine 0.25% compared with bupivacaine 0.25% by the caudal route.
Topics: Amides; Analgesia; Analgesics; Anesthesia Recovery Period; Anesthesia, Caudal; Anesthetics, Inhalati | 1999 |
The effects of plasma fentanyl concentrations on propofol requirement, emergence from anesthesia, and postoperative analgesia in propofol-nitrous oxide anesthesia.
Topics: Adult; Analgesia, Patient-Controlled; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, | 2000 |
The influence of the type of anaesthesia on postoperative pain after kidney transplantation.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Anesthesia; Fentanyl; Halothane; Humans; Iso | 2000 |
Omission of nitrous oxide from a propofol-based anesthetic does not affect the recovery of women undergoing outpatient gynecologic surgery.
Topics: Abortion, Legal; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inha | 2000 |
A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. I. Emergence and recovery profiles.
Topics: Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; H | 2001 |
Small-dose selective spinal anesthesia for short-duration outpatient laparoscopy: recovery characteristics compared with desflurane anesthesia.
Topics: Adjuvants, Anesthesia; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia | 2002 |
Antagonism of fentanyl with naloxone during N2O+O2+ halothane anaesthesia.
Topics: Adult; Aged; Anesthesia, Inhalation; Blood Pressure; Carbon Dioxide; Female; Fentanyl; Halothane; Hu | 1977 |
Anaesthesia time/dose curves IX: the use of hydromorphone in surgical anaesthesia and postoperative pain relief in comparison to morphine.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Child; Clinical Trials as Topic; Dose-Response Relatio | 1976 |
Efficacy of esmolol versus alfentanil as a supplement to propofol-nitrous oxide anesthesia.
Topics: Adjuvants, Anesthesia; Adrenergic beta-Antagonists; Adult; Alfentanil; Ambulatory Surgical Procedure | 1991 |
Efficacy of therapeutic suggestions for improved postoperative recovery presented during general anesthesia.
Topics: Adult; Anesthesia, General; Awareness; Double-Blind Method; Female; Humans; Intraoperative Period; I | 1991 |
Efficacy of therapeutic suggestions for improved postoperative recovery presented during general anesthesia.
Topics: Adult; Anesthesia, General; Awareness; Double-Blind Method; Female; Humans; Intraoperative Period; I | 1991 |
Efficacy of therapeutic suggestions for improved postoperative recovery presented during general anesthesia.
Topics: Adult; Anesthesia, General; Awareness; Double-Blind Method; Female; Humans; Intraoperative Period; I | 1991 |
Efficacy of therapeutic suggestions for improved postoperative recovery presented during general anesthesia.
Topics: Adult; Anesthesia, General; Awareness; Double-Blind Method; Female; Humans; Intraoperative Period; I | 1991 |
Safety and efficacy of alfentanil and halothane in paediatric surgical patients.
Topics: Alfentanil; Anesthesia, Inhalation; Anesthesia, Intravenous; Blood Pressure; Child; Child, Preschool | 1991 |
Effect on outcome of prolonged exposure of patients to nitrous oxide.
Topics: Adult; Anesthesia, Inhalation; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Isofl | 1990 |
[Anesthesia in patients with varicose syndrome].
Topics: Anesthesia; Halothane; Humans; Ketamine; Nitrous Oxide; Pain, Postoperative; Varicose Veins | 1989 |
Low-dose sufentanil as a supplement to halothane/N2O anaesthesia in infants and children.
Topics: Analgesics, Opioid; Anesthesia, Inhalation; Blood Pressure; Child; Child, Preschool; Double-Blind Me | 1988 |
A new method of analgesia for relief of circumcision pain.
Topics: Administration, Topical; Anesthesia, General; Child; Child, Preschool; Circumcision, Male; Double-Bl | 1989 |
Buprenorphine as premedication and as analgesic during and after light isoflurane-N2O-O2 anaesthesia. A comparison with oxycodone plus fentanyl.
Topics: Adult; Analgesia; Anesthesia, Endotracheal; Anesthesia, General; Buprenorphine; Clinical Trials as T | 1987 |
Comparison of trichloroethylene and enflurane as adjuncts to nitrous oxide and relaxant anaesthesia.
Topics: Adjuvants, Anesthesia; Adult; Alcuronium; Anesthesia, Inhalation; Enflurane; Female; Fentanyl; Human | 1987 |
Butorphanol: a double-blind evaluation in postoperative patients with moderate or severe pain.
Topics: Anesthesia, Inhalation; Atropine; Clinical Trials as Topic; Cyclobutanes; Diazepam; Dose-Response Re | 1974 |
42 other studies available for nitrous oxide and Pain, Postoperative
| Article | Year |
|---|---|
Nitrous oxide cryotherapy for treatment of esophageal squamous cell neoplasia: initial multicenter international experience with a novel portable cryoballoon ablation system (with video).
Topics: Aged; Aged, 80 and over; Carcinoma in Situ; Carcinoma, Squamous Cell; Cryosurgery; Esophageal Neopla | 2018 |
The effects of intrathecal and systemic adjuvants on subarachnoid block.
Topics: Adjuvants, Anesthesia; Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic alpha-Agonist | 2014 |
Perioperative outcome after nitrous oxide anaesthesia: an ENIGMA trial.
Topics: Anesthetics, Inhalation; Humans; Nitrous Oxide; Pain, Postoperative; Postoperative Complications; Ra | 2014 |
Refining the anesthesia management of the face-lift patient: lessons learned from 1089 consecutive face lifts.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Androstanols; Anesthesia; Anesthetics, Inhalatio | 2015 |
[Not Available].
Topics: Aged; Analgesics, Non-Narcotic; Humans; Male; Nitrous Oxide; Oxygen Compounds; Pain Management; Pain | 2016 |
The peri-operative management of a cesarean section in a patient with Goldenhar syndrome (GS): A case report.
Topics: Adult; Anesthesia, General; Anesthetics, Inhalation; Bupivacaine; Cesarean Section; Female; Goldenha | 2016 |
Effects of remifentanil versus nitrous oxide on postoperative nausea, vomiting, and pain in patients receiving thyroidectomy: Propensity score matching analysis.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Fe | 2016 |
Independent risk factors for postoperative pain in need of intervention early after awakening from general anaesthesia.
Topics: Adolescent; Adult; Age Factors; Aged; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Ge | 2010 |
Intraoperative nitrous oxide as a preventive analgesic.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; | 2010 |
Nitrous oxide (N(2)O) reduces postoperative opioid-induced hyperalgesia after remifentanil-propofol anaesthesia in humans.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Intravenous; Female; Humans; Hyperalgesia; Lidoc | 2011 |
Prevention of opioid-induced hyperalgesia in surgical patients: does it really matter?
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Female; Humans; Hyperalgesia; Male; Nitrous Oxide; Pai | 2012 |
Effectiveness of pain relief during perineal suturing.
Topics: Adult; Analgesia, Obstetrical; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; | 2002 |
Re: Nitrous oxide (Entonox) inhalation and tolerance of transrectal ultrasound guided prostate biopsy: a double-blind randomized controlled study.
Topics: Administration, Inhalation; Anesthetics, Combined; Biopsy; Double-Blind Method; Humans; Male; Nitrou | 2003 |
Re: Nitrous oxide (Entonox) inhalation and tolerance of transrectal ultrasound guided prostate biopsy: a double-blind randomized controlled study.
Topics: Administration, Inhalation; Anesthetics, Combined; Biopsy; Double-Blind Method; Humans; Male; Nitrou | 2003 |
GABAergic interneurons at supraspinal and spinal levels differentially modulate the antinociceptive effect of nitrous oxide in Fischer rats.
Topics: Analgesics, Non-Narcotic; Animals; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Spi | 2003 |
Laparoscopic cholecystectomy under spinal anesthesia with nitrous oxide pneumoperitoneum: a feasibility study.
Topics: Adult; Anesthesia, Spinal; Bupivacaine; Cholecystectomy, Laparoscopic; Feasibility Studies; Female; | 2003 |
RELIEF OF POST-OPERATIVE PAIN: COMPARISON OF A 25 PER CENT NITROUS-OXIDE AND OXYGEN MIXTURE WITH MORPHINE.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Humans; Morphine; Nitrous Oxide; Oxygen; Oxygen | 1964 |
VALUE OF PREMIXED NITROUS-OXIDE-AND-OXYGEN MIXTURES IN THE RELIEF OF POST-OPERATIVE PAIN. DOUBLE-BLIND TRIAL OF 25 PERCENT NITROUS OXIDE IN OXYGEN, 15 PERCENT NITROUS OXIDE IN OXYGEN, AND OXYGEN.
Topics: Analgesia; Biomedical Research; Double-Blind Method; Humans; Nitrous Oxide; Oxygen; Oxygen Inhalatio | 1964 |
THE USE OF NITROUS OXIDE AND OXYGEN MIXTURES IN THE RELIEF OF POST OPERATIVE PAIN.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthesiology; Drug Therapy; Humans; Nitrous Oxide; Oxygen; Pai | 1964 |
Toxicity after intermittent inhalation of nitrous oxide for analgesia.
Topics: Adult; Analgesia, Patient-Controlled; Anesthetics, Combined; Anesthetics, Inhalation; Drug Interacti | 2004 |
Detection of causal relationships between factors influencing adverse side-effects from anaesthesia and convalescence following surgery: a path analytical approach.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Anesthesia Recovery Period; Anesthetics; Cau | 2004 |
What is the driving performance of ambulatory surgical patients after general anesthesia?
Topics: Adjuvants, Anesthesia; Adult; Ambulatory Surgical Procedures; Anesthesia, General; Anesthetics, Intr | 2005 |
Management of acute and postoperative pain.
Topics: Acute Disease; Anesthetics, Local; Cryosurgery; Electric Stimulation Therapy; Humans; Injections; Na | 1983 |
Postoperative nitrous oxide analgesia and the functional residual capacity.
Topics: Cholecystectomy; Drug Evaluation; Functional Residual Capacity; Humans; Lung Volume Measurements; Mi | 1983 |
Naloxone fails to antagonize nitrous oxide analgesia for clinical pain.
Topics: Adolescent; Adult; Endorphins; Humans; Naloxone; Nitrous Oxide; Pain, Postoperative; Tooth, Impacted | 1982 |
[Relevance of alfentanil as an analgesic in N20 supplemented intravenous anesthesia in ambulatory surgery].
Topics: Adolescent; Adult; Alfentanil; Ambulatory Surgical Procedures; Analgesia; Anesthesia Recovery Period | 1994 |
Morphine, but not inhalation anesthesia, blocks post-injury facilitation. The role of preemptive suppression of afferent transmission.
Topics: Anesthesia, Inhalation; Animals; Injections, Spinal; Isoflurane; Male; Morphine; Naloxone; Neurons, | 1993 |
Sevoflurane-based anesthesia in a patient with myotonia dystrophica.
Topics: Adult; Analgesics, Opioid; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; | 1996 |
[Anesthetic management of a pediatric patient with Cornelia de Lange syndrome].
Topics: Analgesia; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Local; Bupivacaine; Child; De | 1996 |
Use of the laryngeal mask airway during repair of atrial septal defect in children.
Topics: Administration, Rectal; Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Inhalation | 1999 |
Pre-emptive analgesia--why the evidence is conflicting.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Drug Administration Schedule; Humans; Nitrous | 1999 |
[Analgesia using a (50/50) mixture of nitrous oxide/oxygen in children].
Topics: Analgesia; Analgesics; Anesthetics, Inhalation; Child; Humans; Hypoxia; Nitrous Oxide; Oxygen; Pain; | 1999 |
Personality assessment and postoperative analgesia. A study in male patients undergoing elective gastric surgery.
Topics: Adolescent; Adult; Anesthesia, Endotracheal; Anesthesia, Intravenous; Duodenal Ulcer; Humans; Male; | 1976 |
A simple mask for nitrous oxide and oxygen analgesia.
Topics: Analgesia; Humans; Masks; Nitrous Oxide; Oxygen; Pain, Postoperative | 1976 |
[Postoperative analgesia by intra-abdominal administration of nitrous oxide].
Topics: Adult; Humans; Injections, Intraperitoneal; Male; Middle Aged; Nitrous Oxide; Pain, Postoperative | 1975 |
Is fentanyl effective for postoperative analgesia in day-surgery?
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesia; Anesthesia | 1992 |
[Criteria of recovery from caudal anesthesia in children].
Topics: Ambulatory Surgical Procedures; Analgesia, Epidural; Anesthesia Recovery Period; Anesthesia, Inhalat | 1990 |
Comparison of sufentanil-N2O and fentanyl-N2O in patients without cardiac disease undergoing general surgery.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Inhalation; Catecholamines; Female; Fentanyl; Hemodyn | 1987 |
[Nitrous oxide administration for analgesia after open heart surgery].
Topics: Administration, Inhalation; Adult; Aged; Analgesia; Cardiac Surgical Procedures; Female; Humans; Mal | 1988 |
Psychological preparation influences nitrous oxide analgesia: replication of laboratory findings in a clinical setting.
Topics: Adolescent; Adult; Analgesia; Anxiety; Dental Care; Humans; Nitrous Oxide; Pain, Postoperative; Time | 1986 |
Postoperative nitrous oxide analgesia. Administration from air entrainment oxygen masks with a primary flow of Entonox.
Topics: Air; Drug Combinations; Humans; Masks; Nitrous Oxide; Oxygen; Pain, Postoperative | 1986 |
[Tramadol infusion anesthesia with the substitution of enflurane and various nitrous oxide concentrations].
Topics: Adolescent; Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics; Bicarbonates; Blood Pr | 1985 |